Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05580458RecruitingPhase 1/Phase 2
Shingles vaccine study for adults with well-controlled HIV
This Phase 1/2 study tests how safe and how well a shingles (varicella zoster) vaccine works in adults living with HIV whose immune status is measured by CD4 count, plus a healthy comparison group. It may help researchers understand whether the vaccine can safely boost protection in people with HIV.
Bethesda, MarylandAges 18 years+ - NCT05581368Recruiting
Study how cannabis affects blood vessels
This trial tests whether regular cannabis use changes how your blood vessels work, compared with people who do not use cannabis. It may help researchers understand potential effects on heart and circulation health.
London, OntarioAges 19–80 - NCT05582837RecruitingPhase 4
Using migraine medicines to treat Meniere’s disease symptoms
This Phase 4 study tests whether migraine-type medications can help people with active or frequent Meniere’s disease. If you have symptoms like inner-ear episodes, the trial may help find a better way to control them.
Orange, CaliforniaAges 25–85 - NCT05584059Recruiting
Parent coaching for Hong Kong families of special health needs children
This trial tests a parent coaching programme to help parents of children with special health needs in Hong Kong. You may be invited if you answer screening questions and your child’s needs fit specific types that last at least 12 months.
Hong KongAges 21 years+ - NCT05583942Recruiting
Nerve stimulation trial for children with steroid-resistant kidney syndrome
This pilot study tests a device that stimulates nerves in the ear to help children with steroid-resistant nephrotic syndrome. It may improve urine protein and kidney-related outcomes for kids whose standard steroid treatment does not work.
New Hyde Park, New YorkAges 3–17 - NCT05584722Recruiting
Study risk and resilience in pulmonary arterial hypertension
This study looks at how people with pulmonary arterial hypertension (PAH) and certain genetic risks cope and how their bodies respond over time. It may help researchers understand factors linked to better or worse outcomes, and how different people manage the condition.
Nashville, TennesseeAges 15–80 - NCT05586282Recruiting
Study proteins that may worsen fluid leaks in shock
This trial studies specific body proteins to understand why fluid can leak from blood vessels during dangerous shock after infection or heart problems. If you (or your representative) qualify, your team will collect information and possibly samples to see whether these proteins relate to recovery and treatment response.
ParisAges 18 years+ - NCT05587894RecruitingPhase 2
Testing optimized COVID antiviral treatment in immunocompromised adults
This study tests the best combination and timing of antiviral medicines for people with COVID-19 who have weakened immune systems. It aims to improve outcomes in people with mild to moderate illness.
Bordeaux, BordeauxAges 16 years+ - NCT05588063Recruiting
Device-based nerve stimulation for relapse-preventing kidney disease in kids
This trial tests whether a small non-surgical device can help keep children with steroid-sensitive nephrotic syndrome in remission. If it works, it could lower the chance of relapse (kidney flare-ups) and help maintain kidney health.
New Hyde Park, New YorkAges 3–17 - NCT05589714Recruiting
Study your rare eye gene and track retinal disease over time
This study builds a registry and tracks the natural history of rare retinal dystrophies while also testing people for disease-causing gene variants. It may help researchers better understand what causes retinal degeneration and how it progresses.
Little Rock, ArkansasAges 4 years+ - NCT05590637RecruitingPhase 4
Compare antipsychotic medicines for Parkinson or Lewy body psychosis
This study compares two medicines—quetiapine and pimavanserin—in people with psychosis caused by Parkinson’s disease or Lewy body dementia, looking at how they work over time. You might join if you are starting an antipsychotic for the first time and your clinician can safely manage either option.
San Antonio, TexasAges Any age - NCT05590455RecruitingPhase 2
Testing a TNF-blocking drug to reduce death in HIV and TB meningitis
This Phase 2 trial studies whether a TNF-blocking medicine can lower the risk of death in people with HIV who also have TB meningitis. You would receive standard TB meningitis treatment plus the study drug, if you meet the criteria.
Rio de JaneiroAges 18 years+ - NCT05591027RecruitingPhase 1
Testing Centella asiatica for memory problems in older adults
This Phase 1 study tests whether Centella asiatica (a plant-based supplement) is safe and reaches its intended target in people with mild cognitive impairment or early Alzheimer’s disease. It also checks how it affects memory-related brain measures like MRI scans, which is why multiple scans are required.
Portland, OregonAges 60–85 - NCT05592366Recruiting
Testing a hospital tool for unpaid dementia caregivers
This study is testing a care-partner support tool for people who provide unpaid care to a hospitalized adult loved one or partner with dementia-related needs. It may help caregivers and hospitals communicate and coordinate better during a hospital stay.
Madison, WisconsinAges 18 years+ - NCT05592314Recruiting
How dental implant shape affects gum and bone disease rates
This study looks at whether the way a dental implant is restored (the “prosthetic emergence profile,” or how it comes up through the gum) affects how often gum and tissue problems happen around implants. It may help clinicians choose restoration styles that lower the risk of peri-implant diseases.
Sant Cugat del Vallès, BarcelonaAges 18–80 - NCT05592678Recruiting
Study brain and memory test changes in Alzheimer’s or mild issues
This study looks at how well people with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) perform on standardized memory/brain tests. It may help researchers understand changes over time, and whether certain types of brain signals or test results track with the condition.
San Antonio, TexasAges 65–100 - NCT05595408Recruiting
Tracking tumor DNA to predict relapse after upper kidney cancer surgery
This study checks tumor DNA found in blood and urine to see who is at higher risk of the cancer coming back after surgery. It may help doctors identify “minimal residual disease,” meaning tiny amounts of cancer that can remain after treatment.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05595447RecruitingPhase 2/Phase 3
Testing new treatment for Hodgkin lymphoma that came back
This study tests a treatment plan for adults with Hodgkin lymphoma that has returned or did not respond to ABVD chemotherapy. It may help people with a higher-risk pattern of disease, as long as their organ function and overall health meet study limits.
León, GuanajuatoAges 15–90 - NCT05597124RecruitingPhase 2
Exercise program to improve brain health in older Black adults
This Phase 2 study tests whether a structured exercise program can improve brain health in adults age 60 and older who are less active and have early thinking/memory concerns. It may help maintain or improve thinking abilities over time, with medical supervision throughout the study.
Newark, New JerseyAges 60 years+ - NCT05597709Recruiting
Study diabetes patients to measure MAFLD in Jiangsu
This study checks how common a condition called MAFLD is among people with type 2 diabetes in Jiangsu, China. It may help doctors understand how often this liver-related problem occurs and guide future care for people with type 2 diabetes.
Nanjing, JiangsuAges 18 years+ - NCT05598879Recruiting
New heart-cancer visit registry for adults
This study is a “registry,” meaning it collects health information from adults who are getting a new heart (cardio) evaluation related to cancer. It helps doctors better understand heart risks and care needs for different cancer types and treatments.
Weston, FloridaAges 18 years+ - NCT05598632Recruiting
People with atrial fibrillation registry to study stroke risk
This registry study follows people with atrial fibrillation to learn which risk factors are linked to stroke or blood clots traveling through the body. Your information helps improve how doctors predict risk and choose prevention strategies.
Beijing, Beijing MunicipalityAges 18–120 - NCT05600920RecruitingPhase 1/Phase 2
Long-acting IL-7 drug trial for low CD4 immune cells
This Phase 1/2 study tests a long-acting IL-7 medicine to raise low CD4 immune cells in people with idiopathic CD4 lymphopenia. Because this is a dose-escalation study, the goal is to check safety and see if the treatment affects immune cell levels.
Bethesda, MarylandAges 18–75 - NCT05600946Recruiting
Study of body differences in creatine transporter deficiency
This study looks at physical and body features in people with creatine transporter deficiency caused by a specific gene change (SLC6A8). It may help doctors better understand the condition and how it shows up, which can improve future care.
Bethesda, MarylandAges 2–40
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,583 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.