Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,560 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07324330Recruiting
Slowing cognitive decline with exercise in iRBD
This study tests if increasing physical activity can help slow down cognitive (thinking) decline in people with iRBD, a sleep disorder that often leads to Parkinson's or dementia. You'll use a smartphone and a FitBit to track your activity and receive coaching.
Bonn, North Rhine West-FaliaAges 50–80 - NCT02435940Recruiting
Registry for inherited eye vision conditions
This study is a registry, meaning it collects information about people with inherited retinal (retina) diseases. It may help researchers learn how these conditions progress and connect you with future studies or treatments.
Columbia, MarylandAges Any age - NCT07545473Recruiting
Eye Imaging to Detect Brain Disease Markers
This study uses a special camera to photograph the back of your eye in detail. Researchers believe changes in the eye may reflect brain diseases like Alzheimer's or Parkinson's, and this imaging could help detect these conditions earlier.
Melbourne, VictoriaAges 30 years+ - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06542432Enrolling by invitation
Genetic risk test for heart disease prevention
This trial uses a polygenic risk score to see if knowing your genetic risk for coronary artery disease can help prevent a first heart attack. If you have an intermediate 10-year risk and no prior heart events, you may be eligible.
Rochester, MinnesotaAges 40–70 - NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Sun City, ArizonaAges 40–80 - NCT07222800RecruitingPhase 3
Testing a new drug plus chemo for stage 4 colorectal cancer
This study tests a new experimental drug (PF-08634404) combined with standard chemotherapy for people with stage 4 colorectal cancer who have not yet been treated for their advanced disease. The goal is to see if the combination helps shrink or slow the growth of tumors.
Chandler, ArizonaAges 18 years+ - NCT06858319RecruitingPhase 3
Long-term study of zigakibart for IgA nephropathy
This study is for people with IgA nephropathy who completed a previous zigakibart study. It tests whether continuing treatment with zigakibart (given as a shot every two weeks) is safe and helpful over a longer period.
Denver, ColoradoAges 18–100 - NCT07286578Recruiting
Using heart CT scans to guide treatment for blocked arteries
This trial is testing whether a special heart CT scan (coronary CT angiography) can help doctors better understand and treat calcium buildup in your heart arteries. If you have a type of heart disease that might need a stent or other procedure, this study could help decide the best approach.
Boston, MassachusettsAges 18–85 - NCT06189495RecruitingPhase 2
Study of Genakumab for lung scarring from connective tissue disease
This study tests a new injected medication (Genakumab) for people with connective tissue disease-related lung scarring. It aims to see if it helps stabilize or improve lung function safely.
Beijing, Beijing MunicipalityAges 18–75 - NCT06514300Enrolling by invitation
Study of muscle fat in fatty liver disease
This study looks at how fat in the muscles may affect liver disease in people with fatty liver and related conditions like obesity or diabetes. It aims to better understand the connection between muscle fat and liver health.
BrusselsAges 18–75 - NCT07081711Recruiting
Testing new heart MRI technology in volunteers
This study is testing a new way to take pictures of the heart using MRI. It is looking for healthy volunteers to help make sure the technology works correctly.
Cleveland, OhioAges 18 years+ - NCT07607470Recruiting
Vaginal Health Symptom Study with New Testing Method
This study tests a new way to diagnose vaginal infections by collecting samples from the vagina. If you have symptoms like unusual discharge, itching, burning, or odor, this research may help improve how doctors identify what's causing your discomfort.
North Miami, FloridaAges 18 years+ - NCT03233646Recruiting
Retina scans in memory and nerve disorders
This study uses pictures of the back of your eye (retinal imaging) to look for differences in people with neurodegenerative diseases and compares them with people without these conditions. It may help researchers understand eye changes that could connect to brain or nerve health.
Durham, North CarolinaAges 18 years+ - NCT03934957Recruiting
Study of health in people living in Hamburg
This study follows adults living in Hamburg to better understand health and health-related factors over time. You may help researchers learn what influences health in this age group.
HamburgAges 45–74 - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT04454216Recruiting
Liver enzyme gene study for GSD VI or GSD IX
This study looks at the natural history (how the illness typically progresses) in people with GSD VI or GSD IX. It may help doctors better understand disease patterns, which can support future treatments.
Durham, North CarolinaAges birth–90 years - NCT04460872RecruitingPhase 2
Testosterone plus walking training to support bones and muscles
This Phase 2 study tests whether testosterone therapy combined with walking training can improve bone and muscle health after a spinal cord injury. It aims to help men with low testosterone and walking problems by improving strength, body composition, and related health markers.
Gainesville, FloridaAges 18 years+ - NCT04522622RecruitingPhase 4
Teriparatide for low bone turnover in advanced kidney disease
This trial tests teriparatide (a hormone-like bone medicine) to improve bone health in people with advanced chronic kidney disease who are at risk for weak, low-turnover bone. It may help by changing how quickly your bones break down and rebuild.
AalborgAges 18–120 - NCT07699380RecruitingPhase 2
Metabolic study to improve insulin sensitivity in type 1 diabetes
This study tests a new medication to see if it can improve how your body responds to insulin and boost your cells' energy (mitochondrial function). It is for adults with type 1 diabetes who are already on insulin and have good overall health.
Seattle, WashingtonAges 18–69 - NCT04949282Recruiting
Lutetium-177 treatment for advanced somatostatin-positive tumors
This study looks at outcomes for adults with tumors that are advanced (can’t be fully removed or has spread) and are getting worse, where tests show somatostatin receptors. It aims to understand how treatment with lutetium-177 helps people in this situation.
Santiago de Compostela, A CoruñaAges 18–100 - NCT05209568Recruiting
Study of immune reactions after eating gluten
This study looks at how your immune system responds when you eat gluten, including for people with celiac disease. You may be asked to follow a gluten-free diet first and then safely reintroduce gluten so researchers can measure immune changes.
Aurora, ColoradoAges 2–101 - NCT05248412Recruiting
Study how COVID-19 long-term effects impact chronic diseases
This research looks at how the COVID-19 pandemic has affected the health and healthcare of adults with long-term conditions like diabetes, high blood pressure, heart disease, cancer, kidney disease, or chronic lung disease. It compares people who may have been affected by the pandemic and looks at their health and access to care over time.
Hong Kong, Hong KongAges 18 years+ - NCT05332639Recruiting
Risk tracking test for Crohn’s disease in teens
This study checks whether a personalized tool can estimate someone’s risk for Crohn’s disease before symptoms start. It may help families learn early risk and decide on next steps sooner.
Boston, MassachusettsAges 14 years+
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,560 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.