Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,578 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05565833RecruitingPhase 2
Online sleep program for insomnia and thinking problems
This Phase 2 study tests an internet-based sleep program to help older adults with insomnia and related thinking difficulties. It may help improve sleep and reduce how much tiredness and sleep disruption affect daily life.
Charlottesville, VirginiaAges 65 years+ - NCT05569122RecruitingPhase 1
Studying an MRI contrast method in mitochondrial muscle disease
This Phase 1 study tests a special MRI approach (using a contrast agent) to better measure changes in muscles in people with mitochondrial diseases. It also includes some healthy volunteers and other critically ill patients to compare results and check safety.
Philadelphia, PennsylvaniaAges 10–60 - NCT05573490Recruiting
Lifestyle program study for early-onset Alzheimer’s
This study tests a structured lifestyle intervention to help people with early-onset Alzheimer’s disease. It is designed for adults with confirmed Alzheimer’s-related brain changes, and may help with symptoms or day-to-day functioning.
Indianapolis, IndianaAges 40–75 - NCT05573802RecruitingPhase 1/Phase 2
Belantamab and other medicines for new multiple myeloma
This early-phase study tests how safe and effective belantamab mafodotin is when combined with lenalidomide and dexamethasone, plus a medicine called nirogacestat, in people with newly diagnosed multiple myeloma who cannot have stem cell transplant. It may help shrink the cancer and improve outcomes, while doctors track side effects.
AthensAges 18 years+ - NCT05573997Recruiting
Testing new ultrasound measures of heart muscle function in heart failure
This study looks at whether a special kind of heart ultrasound can better measure how well the heart muscle works in people admitted with heart failure. It may help doctors understand heart function using clearer ultrasound “biomarkers” soon after hospital admission.
Thessaloniki, Central MacedoniaAges 18 years+ - NCT05576038Recruiting
Tryptophan to help celiac symptoms improve
This trial tests whether tryptophan (a natural amino acid) can improve symptoms in people with celiac disease who still have symptoms despite following a gluten-free diet. It may help by supporting an internal body signal pathway researchers believe is impaired in some people with celiac disease.
Hamilton, OntarioAges 18–75 - NCT05576818RecruitingPhase 3
Synbiotic add-on for people with Parkinson’s disease
This trial tests whether adding a synbiotic (a mix of probiotics and prebiotics) along with standard Parkinson’s medicines can improve symptoms or health outcomes. It’s mainly for adults with Parkinson’s disease at earlier to mid-stages who take dopamine replacement therapy.
Tanta, El GharbiaAges 45–65 - NCT05578235Recruiting
Surgery for Crohn’s: hand-sewn vs stapled bowel connection
This trial compares two ways of reconnecting the bowel after removing diseased intestine in people with Crohn’s disease. The goal is to see which method works better for healing and short- and longer-term outcomes.
Almere Stad, FlevolandAges 16 years+ - NCT05578495Recruiting
Track daily movement to predict future health problems
This study looks at how active versus sedentary you are (often using a digital signature from your daily routine) to see how it relates to developing multiple health conditions over time. It may help researchers understand which activity patterns are linked with higher risk, especially in certain long-term illnesses.
Clermont-FerrandAges 18–90 - NCT05579392Recruiting
Bright light therapy for gut inflammation in Crohn’s or colitis
This trial studies whether daily bright light can improve gut barrier “leakiness” and reduce inflammation in adults with Crohn’s disease or ulcerative colitis. It compares bright light versus dim light in a crossover design, meaning you may receive both.
Chicago, IllinoisAges 18 years+ - NCT05580666RecruitingPhase 3
Lower death risk by adding azithromycin to HIV treatment
This Phase 3 study tests whether adding azithromycin helps people with advanced HIV disease live longer. You would start (or restart or adjust) HIV treatment within 4 weeks and may also receive azithromycin or a comparison approach to see if outcomes improve.
AbidjanAges 18 years+ - NCT05582200Recruiting
PET brain scan to study inflammation cells in Alzheimer’s
This study uses a special PET brain scan to look at two types of brain immune cells in people with Alzheimer’s. It may help researchers better understand Alzheimer’s and how these cells change over time.
Houston, TexasAges 18–90 - NCT05582993RecruitingPhase 3
Study of rVWF for severe bleeding disorder in children
This Phase 3 trial tests vonicog alfa (an rVWF treatment) to prevent and control bleeding in children with severe von Willebrand disease (vWD). You may be able to join if your child has severe vWD and has been on prior clotting factor treatment with ongoing bleeding despite that care.
Birmingham, AlabamaAges Up to 17 years - NCT05583721RecruitingPhase 2
PET scan study of heart filling and blood flow in sickle cell
This study uses a PET scan to look for links between abnormal heart “filling” problems and how well blood reaches the heart muscle in people with sickle cell disease. The results may help explain early heart changes in sickle cell and guide future care.
Memphis, TennesseeAges 18–21 - NCT05587439Recruiting
Study of inherited genetic risk in lung and related cancers
This study looks for inherited (family-passed) genetic changes that may raise the risk of lung cancer and related thoracic cancers. It may help people and families understand their genetic risk by collecting health information and sometimes specimens from patients and relatives.
Boston, MassachusettsAges 18 years+ - NCT05588167Recruiting
Niemann-Pick type C patient database and genetic data study
This study collects health information and genetic samples from people diagnosed with Niemann-Pick disease type C. The goal is to build a large database that can help researchers better understand the condition and improve future care.
Bethesda, MarylandAges 3 months+ - NCT05590416Recruiting
Adalimumab for early Vogt-Koyanagi-Harada eye inflammation
This trial studies adalimumab to treat a rare, fast-onset eye inflammation called Vogt-Koyanagi-Harada disease. It may help people who can’t use strong steroid treatments or whose disease is not improving quickly with them.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT05596773Recruiting
Village health worker program for chronic disease care in Lesotho
This study tests a community-based care approach using trained village health workers to support people with chronic (long-term) health conditions. It may help your village get easier access to ongoing support, using a tablet-based tool and coaching from health professionals.
MaseruAges Any age - NCT05596786RecruitingPhase 3
Rituximab for worsening inflammatory lung scarring
This trial studies whether rituximab can slow worsening lung scarring (interstitial lung disease) when there is an inflammatory component. You would get rituximab or a placebo (inactive treatment) in a blinded, randomized design to compare safety and effectiveness.
ToursAges 18–100 - NCT05597904Recruiting
Study differences in celiac disease and related skin rash
This study looks at why celiac disease (and a related skin condition called dermatitis herpetiformis) can look different from person to person. It may help researchers understand these “phenotypes” (different patterns) so future care can be better targeted.
TampereAges 18 years+ - NCT05603715RecruitingPhase 2
Pyridostigmine to help constipation in Parkinson’s
This trial tests whether pyridostigmine can improve constipation symptoms in people with Parkinson’s disease. If you have Parkinson’s and functional constipation (with infrequent bowel movements), this study may offer a new medication option and closely track your bowel function.
Burlington, VermontAges 18 years+ - NCT05615779Recruiting
Personalized fiber (B-fructan) diet for inflammatory bowel disease
This trial tests whether a tailored diet high in B-fructans can improve inflammatory bowel disease (ulcerative colitis or IBD-unclassified) in people in mild-to-moderate remission. It may help your gut and reduce bowel inflammation, and it involves colonoscopy and sample collection.
Edmonton, AlbertaAges 6–39 - NCT05617599Recruiting
Checks safety of a stent used in complex heart artery disease
This study looks at how safe and effective a specific stent (SUPRAFLEX CRUZ) is when used in real-world care for people with heart artery blockages in more than one artery. Some participants will also be selected if their heart pumping strength is reduced.
Elche, AlicanteAges 18 years+ - NCT05618626Recruiting
Lifestyle program to prevent fatty liver and heart disease
This trial tests whether a structured lifestyle program—focused on healthy living and resistance exercise—can help prevent fatty liver disease and heart-related problems. It may be helpful if you have early or mild fatty liver changes or risk factors, even if you also have gallstones.
Molina, Maule RegionAges 45–60
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,578 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.