Clinical trials
Disease clinical trials
Below are recruiting disease clinical trials, each written for real people, not researchers. We’re tracking 9,576 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06225544RecruitingPhase 2
Lumasiran for high oxalate patients on hemodialysis
This trial tests a drug called Lumasiran to lower oxalate levels in patients on hemodialysis (a type of kidney dialysis). It may help reduce complications from high oxalate, which can damage organs.
BerlinAges 18–80 - NCT06226909Recruiting
Ultrasound-guided biopsy for lung lining disease
This study tests whether a special ultrasound technique (shear-wave elastography) can help guide biopsies to get better samples from the lining around your lungs. It may be an option if you have a build-up of fluid or thickening in that area.
TaipeiAges 18 years+ - NCT06227910RecruitingPhase 3
Study of vedolizumab with or without upadacitinib for Crohn's disease
This trial tests combining two medicines, vedolizumab and upadacitinib, to see if they work better together than vedolizumab alone for people with moderate to severe Crohn's disease that hasn't responded well to other treatments.
La Jolla, CaliforniaAges 18–65 - NCT06231563RecruitingPhase 2
Ketamine for depression in veterans with Parkinson's
This study tests if ketamine can help treat depression in veterans with Parkinson's disease. It involves several in-person and remote visits, and you will need to avoid certain medications and cannabis for a short time before and during some visits.
San Francisco, CaliforniaAges 40–80 - NCT06232772Recruiting
Biomarkers for early Parkinson's diagnosis
This study looks for new markers in the blood or other samples to help diagnose Parkinson's disease earlier. It compares people with Parkinson's, related conditions (like multiple system atrophy or progressive supranuclear palsy), and healthy volunteers to find differences.
Nanning, GuangxiAges 18–80 - NCT06235112Recruiting
AI Screening for Heart Calcium from Chest CT Scans
This research study uses an artificial intelligence program to screen old chest CT scans for calcium buildup in the heart arteries. If you are between 40 and 75 and have had a chest CT in the last 3 years, this may help identify if you are at risk for heart disease so you can take steps to prevent it.
Boston, MassachusettsAges 40–75 - NCT06235645Recruiting
Detecting lung disease in rheumatoid arthritis with ultrasound
This study tests if a lung ultrasound can detect early signs of lung disease in people with rheumatoid arthritis. It may help you if you have certain risk factors, like being male, older, or a smoker.
ToursAges 18 years+ - NCT06237868Recruiting
TMS for Impulse Control in Parkinson's Disease
This trial tests whether a type of non-invasive brain stimulation called TMS can help reduce impulse control problems (like gambling or compulsive eating) that are caused by Parkinson's medications. It's for people with Parkinson's who are living with these side effects.
Morgantown, West VirginiaAges 18 years+ - NCT06243848Recruiting
Injection vs. surgery for carpal tunnel syndrome
This trial compares two treatments for carpal tunnel syndrome: an ultrasound-guided injection and a surgery to take pressure off the median nerve. It aims to see which one provides better relief for symptoms like numbness and tingling.
AfyonkarahisarAges 18–75 - NCT06244940Recruiting
Genetic testing study for heart defects in pregnancy
This study tests a new way to find genetic causes of congenital heart disease (a heart problem found before birth) using samples from amniocentesis or chorionic villus sampling. It may help parents get a clearer diagnosis and plan for their baby's care.
San Diego, CaliforniaAges 18 years+ - NCT06247397Recruiting
High-flow therapy for long-term oxygen users
This trial tests if adding high-flow oxygen therapy to your usual long-term oxygen therapy can help you breathe better. It is for people with COPD or ILD who use oxygen at home for at least 15 hours a day.
Karlskrona, Blekinge CountyAges 18 years+ - NCT06247631Recruiting
Sleep apnea risk before chest surgery
This study uses a simple questionnaire (STOP-Bang) to check if patients having chest surgery might have undiagnosed sleep apnea or face breathing challenges during surgery. It helps doctors plan safer care.
Ankara, KeçiörenAges 18–65 - NCT06248073Recruiting
Online program and task training for Parkinson's disease
This study tests an online program and task-based training to help people with mild Parkinson's disease improve their movement and reaching ability. It is designed for people who can still sit and reach for objects without major tremors or other health problems.
Linkou DistrictAges 45–70 - NCT06249932RecruitingPhase 4
Empagliflozin for heart failure and end-stage kidney disease
This trial tests whether empagliflozin, a medication for heart failure, can help people who also have end-stage kidney disease and are on dialysis. It aims to see if the drug improves heart function in this group.
Hsinchu, TaiwanAges 20 years+ - NCT06249945RecruitingPhase 4
Empagliflozin for heart failure with preserved ejection fraction and dialysis
This trial tests whether a medicine called empagliflozin (used for diabetes and heart failure) can help people with both heart failure (with preserved pumping ability) and end-stage kidney disease who are on dialysis. The study looks at how the drug affects heart function and overall well-being.
HsinchuAges 20 years+ - NCT06252493Recruiting
PET/MR scan for Crohn's disease scar tissue
This study is testing a new imaging method that uses a special PET/MR scan to see how active Crohn's disease is in your bowel. The scan uses a harmless radioactive tracer that attaches to scar tissue, which may help doctors better understand the disease and guide treatment.
Charlestown, MassachusettsAges 18–99 - NCT06254469RecruitingPhase 3
PET scan study for memory decline with head injury or Alzheimer's risk
This trial uses a special PET scan tracer to see if it can predict who will get worse over time. It is for people with mild memory or thinking problems that may be linked to past head injuries or early Alzheimer's disease.
Evanston, IllinoisAges 45 years+ - NCT06255886RecruitingPhase 4
Treatment for acid reflux in babies under 1 year
This trial tests a treatment for babies under 1 year old who have frequent and troublesome reflux (GERD). It aims to find a safe and effective way to reduce symptoms like crying, feeding problems, and breathing pauses.
Aabenraa, Region SyddanmarkAges 1 month–1 year - NCT06256393Recruiting
Studying inflammatory bowel disease in Nantes
This study collects information and samples from people with active inflammatory bowel disease who need surgery or an endoscopy. It aims to better understand these conditions and improve future treatments.
NantesAges 18 years+ - NCT06256991RecruitingPhase 4
Potassium management for kidney health
This study tests if careful potassium management can help people with chronic kidney disease (CKD) safely take higher doses of blood pressure medicines called ACE inhibitors or ARBs, which are known to protect the kidneys. You may be eligible if you have moderate to advanced CKD and are already on a moderate dose of one of these medications.
GroningenAges 18 years+ - NCT06260059RecruitingPhase 4
Jardiance for adults with congenital heart disease and reduced heart function
This study tests a medicine called Jardiance (an SGLT2 inhibitor) to see if it helps improve heart function in adults with congenital heart disease who have recently experienced a drop in their heart pumping ability. Participants will take the medication alongside standard heart failure treatments.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06260891RecruitingPhase 2
Zinc study for sickle cell disease and bone health
This study tests if taking zinc supplements can improve bone health in people with sickle cell disease. It's for those with certain types of sickle cell disease (SS or S-Beta zero thalassemia) who are not on chronic transfusions or zinc supplements.
Oakland, CaliforniaAges 15–40 - NCT06266442Recruiting
DNA study of M. avium in lung infection
This study looks at the DNA of the bacteria causing your lung infection (Mycobacterium avium) to understand treatment better. It involves analyzing stored samples and may include patients who have been treated before.
Toronto, OntarioAges 18 years+ - NCT06270316RecruitingPhase 1/Phase 2
Gene therapy for classic Fabry disease
This trial tests a new gene therapy called AMT-191 for men with classic Fabry disease who still have symptoms despite standard enzyme replacement therapy. It aims to see if the treatment is safe and can improve symptoms.
Birmingham, AlabamaAges 18–50
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Common questions
- Are there clinical trials for disease?
- Yes. Clin2 currently lists 9,576 recruiting disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.