Clinical trials
DNA Methylation clinical trials
Below are recruiting dna methylation clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06475651Recruiting
DNA patterns in rare prenatal diseases
This study looks at DNA patterns in fetuses or children with rare genetic conditions. It aims to better understand how these patterns relate to diseases that start before birth, which could help with diagnosis and future care.
ParisAges birth–18 years - NCT05904665Recruiting
Blood methylation test to guide follow-up after colon cancer surgery
This study checks a special blood test (circulating tumor DNA methylation) to help guide follow-up after surgery for non-metastatic colon cancer. It may help find whether additional treatment or closer monitoring is needed based on the test results.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07631624Recruiting
Blood test for lung cancer screening in smokers and former smokers
This study tests whether a simple blood test that detects smoking-related changes in DNA can help identify who should get lung cancer screening. Researchers want to see if this test is better at finding people at risk than current methods.
Antwerp, AntwerpenAges 50 years+ - NCT03676647Recruiting
Test DNA methylation from thyroid FNA samples to diagnose cancer
This study looks at a molecular test (DNA methylation pattern) using samples taken during fine-needle aspiration (FNA) of thyroid nodules. It aims to help identify which thyroid nodules that looked “unclear” after the first test may be cancer.
Duarte, CaliforniaAges 19 years+ - NCT06846775Recruiting
DNA test in urine and vaginal samples for endometrial cancer
This study tests if a DNA test in urine and vaginal samples you collect at home can help find endometrial cancer. It compares results from people with the cancer to healthy volunteers.
Aarhus NAges 60 years+ - NCT05954078RecruitingPhase 3
ctDNA-guided chemotherapy after colon cancer surgery
This trial checks whether a special blood test (ctDNA methylation) can help decide the best chemotherapy after surgery for people at higher risk of colon cancer coming back. It may help spare some patients unnecessary treatment while aiming to improve outcomes for those likely to relapse.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07400835Recruiting
Using DNA markers to find endometrial cancer in postmenopausal bleeding
This trial tests whether DNA changes in urine, vaginal, or cervical samples can help find endometrial cancer earlier in women with postmenopausal bleeding. If you are having tests for this bleeding, your samples could help improve detection.
Aarhus NAges Any age - NCT05737953Recruiting
Testing a lab test to identify pancreatic cyst tumor type
This study builds a “molecular marker” lab model using pancreatic cyst fluid taken during planned pancreatic surgery. It aims to help tell which pancreatic cystic tumors are which, based on fluid analysis.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06167967Recruiting
Blood test for chemotherapy guidance in stage 3 colorectal cancer
This study uses a blood test to check for tumor DNA after surgery, which may help doctors decide if you need additional chemotherapy. It is for people with stage 3 colorectal cancer that is removed by surgery.
Hanzhou, ZhejiangAges 18–75 - NCT07741435Recruiting
Simple blood, urine, and saliva test to find cancer early
This study tests a new way to find cancer by looking at DNA in blood, urine, and saliva. It may help detect cancer earlier and monitor how well treatment works.
Bogotá, Bogota D.C.Ages 18 years+ - NCT05229341Recruiting
Testing DNA “methylation” to evaluate thyroid nodule samples
This study looks at patient tissue from needle biopsies to see if DNA “methylation” patterns can help diagnose and guide treatment for thyroid nodules. You might benefit by helping improve how these nodules are evaluated, using information from your biopsy sample and medical data.
Duarte, CaliforniaAges 18 years+ - NCT07874542Recruiting
Blood test to help classify kidney masses before surgery
This study looks at whether a simple blood test can help doctors tell if a kidney mass is cancer before surgery. It aims to improve how kidney masses are classified and guide treatment decisions.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05727228Recruiting
Risk screening for HPV after LEEP
This study looks at how to sort people into higher- or lower-risk groups after abnormal HPV testing treatment (LEEP), using repeat HPV and Pap (cytology) tests. It may help improve follow-up plans by identifying who needs closer monitoring after LEEP.
Randers, Central JutlandAges 23–64 - NCT06305091Recruiting
DNA Changes in Veterans Exposed to Burn Pits
This study looks for DNA changes in veterans who were exposed to open burn pits during deployment. It aims to understand health risks from these exposures.
North Little Rock, ArkansasAges 25–70 - NCT04814407Recruiting
Test blood and other markers to detect early lung cancer
This study looks for new “epigenetic” signals in blood (signals about how genes are turned on/off) to help detect lung cancer early. You might be able to join if you are being evaluated for possible lung cancer or have small, unclear spots on a lung CT scan.
TaipeiAges 20 years+ - NCT05504772Recruiting
Personalized genetic testing for children with cancer
This trial studies how personalized (tailored) genetic testing can help guide care for children with cancer. It may help match treatment choices to each child’s genetic risk, and it includes optional return of germline (inherited) test results.
AdelaideAges birth–25 years - NCT07738003Recruiting
Perinatal Autism Genetics and Epigenetics Study
This study looks at genetics and other factors that may be linked to autism. Pregnant women in their first or second trimester are invited to join, and their babies will be followed to see how they develop.
Iowa City, IowaAges birth–50 years - NCT07587268Recruiting
Understanding Your Appendiceal Cancer Through Genetic Testing
This research study uses genetic and molecular testing on archived tumor samples to better understand appendiceal cancer and predict how it may progress. The goal is to help doctors personalize treatment plans based on the specific characteristics of your cancer.
Durate, CaliforniaAges 18 years+ - NCT06628895Recruiting
Modified Poco-Poco exercise for pre-frailty
This study tests whether a special exercise routine called Modified Poco-Poco can improve frailty and certain biological markers (DNA changes, GDF15, and Lamin A). It may help people who are beginning to feel weaker and want to try a gentle exercise program.
Bandung, West JavaAges 60 years+ - NCT07176962Recruiting
Blood test for early detection of bile duct cancer
This study is testing a new blood test that looks for signs of DNA changes linked to biliary tract cancer. It aims to see if the test can find these cancers early. If you have biliary tract cancer or a high suspicion of it, you may be able to help.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07182214Recruiting
Lung cancer detection using a blood test for early signs
This study uses a blood test to look for tiny genetic markers (miRNA and DNA methylation) that may help detect lung cancer early. If you have a lung nodule or mass found on a CT scan and haven't had treatment yet, you may be able to join.
HsinchuAges 18 years+ - NCT06955624Recruiting
Sorting DNA changes to better diagnose nerve conditions
This study uses advanced DNA analysis to understand confusing genetic test results in people with brain or nerve diseases. It aims to improve diagnosis by reclassifying uncertain genetic findings.
RouenAges Any age - NCT06490003Recruiting
Predicting chemotherapy success for esophageal cancer
This trial looks at whether a biopsy taken before chemotherapy can help predict how well the treatment will work for people with esophageal squamous cell carcinoma. It aims to improve future treatment decisions.
Chūō, YamanashiAges 20 years+ - NCT06476067Recruiting
Predicting early esophageal cancer return after surgery
This trial uses stored tumor tissue to try to predict if esophageal cancer will come back early after surgery. It is for people who had surgery only (no chemo or radiation) and have been followed for at least 2 years.
Nagoya, Aichi-kenAges 20 years+
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Common questions
- Are there clinical trials for dna methylation?
- Yes. Clin2 currently lists 33 recruiting dna methylation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dna methylation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dna methylation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.