Clinical trials · Boston, MA
Down Syndrome clinical trials in Boston
We’re tracking 181 recruiting down syndrome studies with a site in or near Boston — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT02050113Recruiting
Custom endograft repair for complex aortic aneurysms
This trial tests custom-made and doctor-modified grafts to treat complex bulges in the aorta (the body’s main artery) or the part going into the pelvis. It may help people who cannot use standard approved devices or who need treatment urgently because waiting is unsafe.
Worcester, MassachusettsAges 18 years+ - NCT03452774Recruiting
AI matches your cancer tests to possible treatment trials
This trial uses an AI system to help match people with certain cancer types and specific tumor test results (like gene or protein markers) to relevant clinical trials. It may help you and your doctor find studies that fit your cancer biology faster.
Worcester, MassachusettsAges Any age - NCT07020819RecruitingPhase 3
Study of tanruprubart for people with Guillain-Barré syndrome
This trial tests a new medicine, tanruprubart (also called ANX005), for people with Guillain-Barré syndrome. It aims to see if the drug can help improve recovery when given soon after symptoms start.
Worcester, MassachusettsAges 12–85 - NCT05011331Recruiting
Custom pillow study for better shoulder-area sleep
This trial tests whether a specially made pillow can help people with rotator cuff problems sleep better without surgery. You would use the pillow and answer questions about your sleep quality.
East Providence, Rhode IslandAges 18 years+ - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT06099288Recruiting
Strong families start at home: A healthy eating study for Latinx families
This study tests a program to help families eat healthier together at home. It is for Latinx caregivers of young children and involves recording a few meals to see how the program helps.
Providence, Rhode IslandAges 18 years+ - NCT07545759RecruitingPhase 2
Testing brenipatide for IBS with diarrhea symptoms
This study tests whether a new medication called brenipatide can help people with IBS-diarrhea (IBS-D) reduce belly pain and loose stools. IBS-D is a condition where the intestines move too quickly, causing frequent diarrhea and discomfort.
Providence, Rhode IslandAges 18–75 - NCT06144957Enrolling by invitation
SLC13A5 deficiency natural history study (US only)
This study follows people with SLC13A5 deficiency (a rare genetic condition that affects brain development) to learn more about the disease over time. It collects health information, assessments, and samples to help understand the condition and plan future treatments.
Providence, Rhode IslandAges Any age - NCT05701917Recruiting
Clot-busting device versus blood thinners for leg clot
This study compares a clot-removal device (ClotTriever) plus standard care versus standard blood thinners alone for a deep vein clot in the leg. It aims to see which approach better improves leg symptoms and outcomes.
Providence, Rhode IslandAges 18 years+ - NCT05918861RecruitingPhase 3
Tested heart-risk drug for people with recent heart-attack genetics
This trial studies whether dalcetrapib can lower future heart and blood-vessel risk in people who recently had an ACS (acute coronary syndrome, often a heart attack or unstable chest pain) and have a specific genetic marker. It may help people like you by targeting a risk pathway related to that genetic background.
Providence, Rhode IslandAges 45 years+ - NCT05702645Recruiting
Down syndrome long-term study after leukemia treatment
This study follows children and young adults with Down syndrome who have survived acute leukemia (ALL or AML) to learn about their longer-term health after treatment ends. It may help families and doctors understand what health problems to watch for and how to provide better follow-up care.
Providence, Rhode IslandAges 6–39 - NCT07545772RecruitingPhase 2
Testing Brenipatide for Constipation-Focused IBS
This trial tests a new medicine called brenipatide to see if it can help people with IBS-C (irritable bowel syndrome with constipation). The study focuses on whether the drug reduces belly pain and improves bowel movements in people whose main symptom is hard or infrequent stools.
Providence, Rhode IslandAges 18–75 - NCT07144631Recruiting
Nerve stimulation for restless legs in pregnancy
This trial tests if a small nerve stimulation device can safely and effectively reduce restless legs symptoms in pregnant people. If you are between 21 and 26 weeks pregnant with a confirmed diagnosis of restless legs syndrome (RLS), you may be eligible.
Providence, Rhode IslandAges 18 years+
Hear when a new Down Syndrome trial opens near Boston, MA
We’ll email you when one opens near Boston, MA — at most once a week, no account needed, unsubscribe anytime.
Down Syndrome trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting down syndrome studies listed above.
- Brown University · 3 studies
- Rhode Island Hospital · 3 studies
- University Gastroenterology · 2 studies
- Massive Bio SYNERGY-AI site
- Research Site
- UMass Memorial Medical Center
- University of Massachusetts Chan Medical School
- University Orthopedics
What taking part in a down syndrome study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting down syndrome studies in Massachusetts.
Common questions
- Are there down syndrome clinical trials near Boston?
- Yes. We're currently tracking 181 recruiting down syndrome studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a down syndrome study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New down syndrome studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.