Clinical trials · Chicago, IL
Down Syndrome clinical trials in Chicago
We’re tracking 127 recruiting down syndrome studies with a site in or near Chicago — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT03568669Recruiting
Testing thinking and learning in congenital central hypoventilation syndrome
This study looks at thinking and memory in people with congenital central hypoventilation syndrome (CCHS) to better understand how the condition affects the brain. It may help researchers measure changes over time and guide future care.
Chicago, IllinoisAges 3–85 - NCT04507997Recruiting
Study of the natural course of Angelman syndrome
This study follows people with Angelman syndrome to understand how their symptoms and development change over time. It may help researchers better describe the condition and support future treatments.
Chicago, IllinoisAges Any age - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Chicago, IllinoisAges 18 years+ - NCT05127226RecruitingPhase 1/Phase 2
Test drug safety for Angelman syndrome in young children
This early-phase study tests a new experimental medicine called ION582 to see if it is safe, tolerable, and how the body processes it in people with Angelman syndrome. It may also look at early signs of how the medicine affects the brain and body, which could guide future treatments.
Chicago, IllinoisAges birth–50 years - NCT04571658Recruiting
NEPTUNE Match study linking you to possible kidney research trials
This study is an add-on process that uses information from the NEPTUNE kidney study to see whether you might be able to join other kidney research trials. It may help connect eligible people with appropriate new treatment studies when they become available.
Chicago, IllinoisAges 1–80 - NCT01209000Recruiting
Study for children with new kidney protein loss
This study is for children (and some newly diagnosed patients) who have nephrotic syndrome—kidneys leaking a lot of protein. It aims to better understand the kidney condition (sometimes using biopsy) and support future care decisions.
Chicago, IllinoisAges Up to 80 years - NCT02852031Recruiting
Care program for newborns needing the Norwood procedure
This trial focuses on improving care for babies born with certain complex heart conditions where only one pumping chamber works. It is meant for babies (including unborn babies) who are planned to have the Norwood procedure, which is a common early surgery.
Chicago, IllinoisAges Up to 1.3 years - NCT07742735RecruitingPhase 3
Study of apraglutide for short bowel syndrome with intestinal failure
This study tests a new medicine called apraglutide, given as a shot, to see if it can help adults with short bowel syndrome and intestinal failure reduce their need for intravenous nutrition (parenteral support). The study compares apraglutide to a placebo (a shot with no medicine) to check if it is safe and effective.
Maywood, IllinoisAges 18 years+ - NCT05750212Recruiting
Study of pelvic pain health and overlapping pain conditions
This study looks at women’s chronic pelvic pain that comes with other common pain conditions. It may help researchers understand what supports pelvic and pelvic-floor health when pain has lasted for months.
Maywood, IllinoisAges 21–80 - NCT05654922RecruitingPhase 3
Prevent lung transplant airways scarring with ARINA-1
This Phase 3 trial tests ARINA-1 to slow or prevent worsening lung transplant scarring in the breathing tubes (bronchiolitis obliterans). It may help people who are showing early decline in lung function but are not yet at advanced disease.
Maywood, IllinoisAges 18–75 - NCT06701669RecruitingPhase 2
Study of Paridiprubart for moderate to severe ARDS
This trial tests a new medicine called paridiprubart to see if it can help people with moderate or severe acute respiratory distress syndrome (ARDS), a serious lung condition. It may be an option if you have low oxygen levels and no known allergy to the drug.
Evanston, IllinoisAges 18 years+ - NCT06701682RecruitingPhase 2
Study of vilobelimab for moderate to severe ARDS
This trial tests a drug called vilobelimab for people with moderate or severe ARDS (a serious lung condition). It aims to find if this treatment can help improve breathing and outcomes.
Evanston, IllinoisAges 18 years+ - NCT06007547RecruitingPhase 4
Preventive surfactant therapy for preterm babies
This trial tests whether giving surfactant (a foam that helps lungs stay open) before breathing problems start can help very premature babies (born before 30 weeks) breathe better. It might reduce the need for a breathing tube.
Evanston, IllinoisAges Up to 15 minutes - NCT06074380RecruitingPhase 4
Surfactant therapy comparison for preterm infants
This trial compares a new method of giving surfactant (a substance that helps babies' lungs work better) to preterm infants who have breathing problems. The goal is to see if giving surfactant through a thin tube without a breathing tube works as well as the usual method.
Evanston, IllinoisAges Up to 2 days - NCT06703073RecruitingPhase 2
Testing new treatments for acute respiratory distress syndrome (ARDS)
This trial is testing new treatments for people with ARDS, a serious lung condition. The goal is to find therapies that help patients breathe better and recover faster. If you or a loved one has ARDS, this study may offer access to experimental treatments.
Evanston, IllinoisAges 18 years+ - NCT06701656RecruitingPhase 2
Testing bevacizumab for breathing problems from ARDS
This trial tests if bevacizumab can help people with ARDS (a serious lung condition) breathe better. It is for patients with mild, moderate, or severe ARDS who are already in the hospital.
Evanston, IllinoisAges 18 years+ - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT07422480RecruitingPhase 3
Comparing elritercept to epoetin alfa for anemia in MDS needing transfusions
This trial tests a new drug called elritercept against a standard treatment, epoetin alfa, for people with a low-risk form of MDS who need regular blood transfusions for anemia. The goal is to see if elritercept works better to reduce the need for transfusions.
Skokie, IllinoisAges 18 years+ - NCT07519395RecruitingPhase 2
Camlipixant for abdominal symptoms in IBS-D and IBS-M
This study tests whether a new drug called camlipixant can reduce belly pain and other uncomfortable symptoms in people with irritable bowel syndrome that causes diarrhea or mixed symptoms. The trial compares camlipixant to a placebo (inactive pill) to see if it works better.
Oak Lawn, IllinoisAges 18–80 - NCT07280468RecruitingPhase 4
Personalized sleep apnea treatment for Down syndrome
This study tests if a treatment chosen based on your specific type of sleep apnea works better for people with Down syndrome. It looks for participants who have sleep apnea but are not already using a CPAP machine regularly.
Park Ridge, IllinoisAges 6 years+ - NCT03339128RecruitingPhase 2
Eluxadoline for diarrhea-predominant IBS in children
This trial tests whether eluxadoline can reduce symptoms of IBS with diarrhea (IBS-D) in children ages 6 to 17. It also asks families to track symptoms with a daily diary to measure whether treatment helps over the study period.
Park Ridge, IllinoisAges 6–17 - NCT04165109Recruiting
Down syndrome study to test memory and thinking changes
This study enrolls adults with Down syndrome to better understand how thinking and memory develop and change over time. It may help by building a “trial-ready” group and by measuring thinking in a careful, consistent way.
Park Ridge, IllinoisAges 25–55 - NCT05052606Recruiting
Turner syndrome patient registry study
This is a registry study that collects health information from people who have Turner syndrome. It helps researchers better understand the condition and guide future care.
Glenview, IllinoisAges Any age - NCT07421167RecruitingPhase 2
Ianalumab with TPO-RA for immune thrombocytopenia
This trial tests a new drug called ianalumab combined with a standard platelet-boosting medicine (TPO-RA) for adults with immune thrombocytopenia (ITP) or Evans syndrome. The goal is to see if the combination is well-tolerated and helps raise platelet counts.
Hinsdale, IllinoisAges 18 years+
Hear when a new Down Syndrome trial opens near Chicago, IL
We’ll email you when one opens near Chicago, IL — at most once a week, no account needed, unsubscribe anytime.
Down Syndrome trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting down syndrome studies listed above.
- Endeavor Health · 4 studies
- Loyola University Medical Center · 3 studies
- NorthShore University HealthSystem-Evanston Hospital · 3 studies
- Advocate Medical Group Adult Down Syndrome Center · 2 studies
- Ann & Robert H. Lurie Children's Hospital of Chicago · 2 studies
- John H Stroger Jr Hospital of Cook County · 2 studies
- Rush University Medical Center · 2 studies
- Advocate Children's Hospital - Oak Lawn
What taking part in a down syndrome study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting down syndrome studies in Illinois.
Common questions
- Are there down syndrome clinical trials near Chicago?
- Yes. We're currently tracking 127 recruiting down syndrome studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a down syndrome study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New down syndrome studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.