Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06977724RecruitingPhase 1
Testing a new drug for lupus, sjogren's, and rheumatoid arthritis
This study tests an experimental medicine given by IV infusion to see if it is safe and helps reduce symptoms of lupus, sjogren's disease, or rheumatoid arthritis. It is an early-phase trial, so the main goals are checking side effects and how the drug behaves in the body, but it will also look at how well it works.
Avon Park, FloridaAges 18–75 - NCT06361641Recruiting
Study of immune cells in blood cancers
This study looks at immune cells (monocytes) in people with certain blood cancers. Researchers want to understand how these cells behave and change over time. You can join if you are newly diagnosed and haven't started treatment yet.
Angers, Maine et LoireAges 18 years+ - NCT07190690Recruiting
Comparing two drug-coated stents for heart attack patients
This trial compares two types of drug-coated stents (one with sirolimus, one with everolimus) in people who have had a heart attack or unstable angina and need a stent. It aims to see which stent works better for new blockages in the heart arteries.
AlicanteAges 18 years+ - NCT04893226Recruiting
Time-restricted eating for postmenopausal metabolic risk
This trial studies whether limiting when you eat each day can improve blood sugar and other health markers in postmenopausal women with prediabetes or metabolic risk factors. It may help your body’s metabolism if your sleep and daily routine can stay fairly consistent.
Lexington, KentuckyAges 45–65 - NCT07502586Recruiting
Genetic study for Turner syndrome and family
This study looks at the genetic causes of Turner syndrome. It involves people with Turner syndrome and their family members to learn more about the condition. If you or your family member has Turner syndrome, this study may help answer questions about genetics and health.
Bethesda, MarylandAges 1 day–110 years - NCT06430697Recruiting
Paracetamol's effect on blood pressure in ICU patients
This trial measures how a common painkiller, paracetamol, affects blood pressure in intensive care patients. If you are in the ICU and your doctor has ordered paracetamol, this study may help understand its hemodynamic effects.
NiceAges 18 years+ - NCT06066996RecruitingEarly Phase 1
Study of withdrawal symptoms when people vape less
This study looks at what happens when people who vape nicotine daily try to cut back. Researchers want to understand withdrawal symptoms and find better ways to help people reduce or quit vaping.
Baltimore, MarylandAges 21–55 - NCT05625867Recruiting
After–ICU follow-up program to improve life quality
This study tests a structured follow-up consultation after a stay in an intensive care unit (ICU) to see whether it improves quality of life. You may be asked to join regular interdisciplinary visits after your ICU stay.
DijonAges 18 years+ - NCT06476795Recruiting
Grape pomace from chardonnay for heart and gut health in postmenopausal women
This study tests if consuming a powder made from chardonnay grape pomace (the leftover skins and seeds from winemaking) can improve gut and heart health in postmenopausal women. You may be a good fit if you are between 45-70, have gone through menopause, and have higher levels of blood fats called triglycerides.
Davis, CaliforniaAges 45–70 - NCT02780297Recruiting
Study of rare stone-causing kidney conditions
This study is for people with certain rare kidney conditions that can cause kidney stones. It aims to learn how these conditions behave over time and may help improve future care.
Birmingham, AlabamaAges Any age - NCT06776549Recruiting
Cooling or normal temperature after cardiac arrest with ECMO
This trial tests if cooling the body (hypothermia) or keeping normal body temperature (normothermia) after emergency heart-lung support (ECMO) improves survival in adults who had a cardiac arrest outside the hospital.
Kurume, FukuokaAges 18–75 - NCT03223077Recruiting
Study of gut germs in new Campylobacter stomach illness
This trial studies how your gut germs (microbiome) and gut lining change during a new bout of Campylobacter infection. It may help researchers understand what drives symptoms and how the gut recovers.
Rochester, MinnesotaAges 18–80 - NCT06467149Recruiting
Comparing Frailty Screenings in Older Breast Cancer Patients
This study compares different ways to check frailty (a measure of how well your body handles stress) in women with breast cancer who are 50 or older. The goal is to find which screening tool best predicts health outcomes during treatment.
ChongqingAges 50 years+ - NCT06014931Recruiting
Recovery support after ICU stay
This study uses telehealth to help older adults recover after a serious ICU illness, like being on a breathing machine or having sepsis. It tests whether virtual check-ins can improve your recovery at home.
Columbus, OhioAges 45 years+ - NCT04173715Recruiting
Study measuring movement and behavior in older adults
This study checks how well you move and how you behave during simple tasks. It may help researchers understand physical function and activity patterns in older adults.
ToledoAges 65 years+ - NCT07749092Recruiting
Kimchi powder for gut health in IBS
This study tests whether taking kimchi powder (a dried form of the fermented cabbage dish) can improve gut health and symptoms in people with diarrhea-predominant IBS. You'll avoid regular kimchi for about 2 months, then take the powder daily and track how you feel.
YangsanAges 20–70 - NCT07002710Recruiting
Long-term ventilation and inflammation study
This study looks at how long-term inflammation affects the breathing of people who have been on a ventilator for 10 days or more. It aims to help doctors better understand and support your recovery.
TaipeiAges 20 years+ - NCT07018960Recruiting
Chest wall repair with custom 3D-printed titanium implant
This study is testing a new way to repair large chest wall defects using a custom-made 3D-printed titanium implant. It may help people who need chest wall reconstruction after cancer surgery, a bad injury, or damage from infection or radiation.
Cruces, Basque CountryAges 18 years+ - NCT06916520RecruitingPhase 4
Reduced dose prasugrel alone after stent placement
This trial tests if a lower dose of prasugrel, taken alone (without aspirin), is safe and works well for people who have had a stent placed for chest pain or a heart attack. It might be an option for those who need to simplify their medication routine.
AmsterdamAges 18 years+ - NCT06979531RecruitingPhase 2
A study of IMVT-1402 for Sjogren's disease with moderate to severe symptoms
This trial tests an experimental drug, IMVT-1402, in adults with primary Sjogren's disease who have moderate to severe symptoms. The goal is to see if it can reduce disease activity safely.
Covina, CaliforniaAges 18–74 - NCT06958016Recruiting
Tryptase levels in stable coronary artery disease
This study looks at levels of tryptase, a protein in your blood, in people with stable coronary artery disease. It aims to see if these levels are linked to heart health, which could help doctors better understand and manage your condition.
Athens, AtticaAges 18–85 - NCT06967441Recruiting
Respiratory viruses and acute heart failure study
This trial looks at whether a respiratory virus might be triggering your heart failure. It will test your nasal swab for viruses to help doctors understand and treat your condition better.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06971601Recruiting
Testing physical exams for kneecap fat pad syndrome
This study aims to find out if simple physical exam tests can accurately diagnose impingement of the fat pad behind the kneecap. You would get a clinical exam and an MRl to compare the results, so researchers can see which tests best identify the problem.
Saint-MauriceAges 18–70 - NCT06839690Recruiting
Comparing two exercises for De Quervain tenosynovitis
This study compares two types of exercises (sub-maximal isometric training vs eccentric training) to see which one helps more with thumb pain and tenderness caused by De Quervain tenosynovitis. You may qualify if you have had thumb pain for at least 3 weeks and meet certain diagnostic tests.
Rawalpindi, Punjab ProvinceAges 21–50
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,201 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.