Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05326919Recruiting
Study biobank for people newly diagnosed with certain blood cancers
This study follows people who are newly diagnosed (and haven’t been fully treated yet) with specific leukemia or related blood disorders to help researchers learn which treatments may work best. It may help by connecting you to a larger “precision medicine” patient group for future research.
BobignyAges Any age - NCT06371937Recruiting
Heart and blood vessel disease biobank study
This study creates a collection of skin cells (turned into stem cells in a lab) from people with various heart and blood vessel conditions. It aims to find new ways to understand and treat these diseases.
London, OntarioAges 18–80 - NCT07842536Recruiting
Goji berry extract for dry eye disease
This trial tests whether a supplement made from goji berries can help people with dry eye disease. Dry eyes happen when your eyes do not make enough tears or the tears evaporate too quickly, which can cause discomfort and blurry vision. The study aims to see if this natural supplement improves symptoms and signs of dry eye.
Hong Kong, Hong KongAges 18–60 - NCT05534568Recruiting
Parent support program for families affected by pregnancy substance use
This program aims to help mothers and young children get safer, better support services when substance use occurred during pregnancy. It may help connect you (or your child) to the right community resources and reduce risk of ongoing alcohol or drug exposure.
Oklahoma City, OklahomaAges 18 years+ - NCT06440070Recruiting
Ultrasound-guided needle thread release for carpal tunnel
This trial tests a new, less invasive way to release the tight ligament in the wrist that causes carpal tunnel syndrome. It uses ultrasound to guide a curved needle and thread to cut the ligament, which may lead to less pain and faster recovery.
Guangzhou, GuangdongAges 40–70 - NCT06427694Recruiting
Long-Term Follow-Up of Low-Dose IL-2 After Heart Attack
This study is checking on people who finished a previous trial (IVORY) that tested a low-dose treatment called IL-2 for reducing inflammation after a heart attack. It will see how they are doing over time and if the treatment helped their heart health.
Cambridge, CambridgeshireAges 18–85 - NCT06412536Recruiting
Heart, weight, and hormone trial screening survey
This trial is a quick survey to find out if you may be eligible for future studies on heart health, weight, or hormone-related conditions. It helps researchers match you with the right treatment options.
Brooklyn, New YorkAges 18 years+ - NCT04040777Recruiting
Cardiometabolic risk registry for adults
This study is a health registry that collects information about risk factors for heart and metabolic problems in adults. It may help doctors better understand who is at higher risk and guide future prevention strategies.
Pilar, Buenos AiresAges 18 years+ - NCT06444321Recruiting
Integrated care for frail patients with heart failure
This trial tests a special care program for people with both frailty (being weak or vulnerable) and heart failure (when the heart doesn't pump well). The program brings together different types of support to help you manage your health better after a hospital stay.
Drammen, AkershusAges 18 years+ - NCT07839234Enrolling by invitation
Personalized breathing support for lung injury patients
This trial tests a new way to adjust breathing machine settings for people with a lung condition called ARDS. The adjustments are based on detailed monitoring of the heart and lungs, aiming to improve recovery.
Xiamen, FujianAges 18 years+ - NCT07834177Recruiting
Comparing two neck and spine movement exercises for chronic neck pain
This study compares two types of gentle neck and spine movements (called 'glides') to see which one works better for people with chronic neck pain related to 'upper cross syndrome' (a pattern of tight and weak muscles in the neck and shoulders). The goal is to find a more effective way to reduce pain and improve posture.
Islamabad, Punjab ProvinceAges 20–40 - NCT07836088Recruiting
Ultrasound muscle check for metabolic health
This study uses ultrasound scans to measure muscle mass in people with metabolic conditions like type 2 diabetes and obesity. It may help doctors understand how these conditions affect muscles and could lead to better care.
Zhangzhou, FujianAges 18 years+ - NCT05280028Recruiting
Hormone treatment for overactive bladder and mood symptoms
This trial studies whether hormone treatment can improve overactive bladder symptoms, sexual well-being, mood (depressive symptoms), and body “autonomic” function (automatic body functions like heart rate and sweating) in post-menopausal women. It may help by targeting menopausal changes that can affect these symptoms.
Banqiao District, New TaipeiAges 20 years+ - NCT05640635Recruiting
Testing inflammation changes in people on ECMO
This study looks at inflammation during ECMO (a heart-lung bypass machine) and while people are being weaned off it. It may help doctors better understand which patients are improving safely during ECMO and when to reduce support.
Tübingen, Baden-WurttembergAges 18 years+ - NCT07828847Recruiting
Exercise and muscle health in older adults with diabetes
This study looks at how exercise affects muscle cell function in older adults with type 2 diabetes and frailty. It may help find ways to improve strength and independence in aging.
ValenciaAges 18–83 - NCT07829887Recruiting
Measuring brain oxygen after cardiac arrest
This study tests a device that measures oxygen levels in the brain during recovery from cardiac arrest. It aims to see if monitoring brain oxygen helps doctors make better treatment decisions after the heart restarts.
Calgary, AlbertaAges Any age - NCT07833280Recruiting
Pelvic pain, movement, sleep, and quality of life in women
This study looks at how chronic pelvic pain affects movement, sleep, and daily life in women. It may help find better ways to support women with this condition.
Kırşehir, MerkezAges 18–65 - NCT07833020Recruiting
Gyrotonic exercise for teens with lupus after intensive care
This study tests whether a special exercise program called Gyrotonic can help teenagers with childhood lupus recover after a stay in the intensive care unit (ICU). The exercises aim to improve strength and movement, which may be affected after such a serious illness.
Dokki, Giza GovernorateAges 13–17 - NCT06477549RecruitingPhase 2
Comparing Two Drug Combinations for Stem Cell Transplant
This study compares two different drug combinations (BeFluBu and FluBuRux) used before a stem cell transplant from a half-matched (haploidentical) donor. The goal is to see which combination works better to prepare your body for the transplant and control your blood cancer.
Saint PetersburgAges 18–75 - NCT04524247Recruiting
Testing a custom stent graft for frail aortic aneurysms
This study looks at a specialized, customized stent graft to treat certain aneurysms (bulges) of the aorta in people who may be considered frail. It’s meant to see how well the device works and how safely it can be used in patients who fit specific aneurysm patterns.
Los Angeles, CaliforniaAges 18 years+ - NCT07821034Recruiting
Reiki therapy for women with fibromyalgia
This study tests whether Reiki, a gentle hands-on healing technique, can help reduce pain and improve well-being in women with fibromyalgia. Participants will receive Reiki sessions and their symptoms will be tracked over time.
Diamantina, Minas GeraisAges 18 years+ - NCT07822230Recruiting
Dietary guidance for reducing menopause symptoms in overweight women
This trial tests whether a diet based on Brazilian dietary guidelines can help reduce menopause symptoms (like hot flashes and mood changes) in overweight or obese women. If you're in this stage and looking for non-medical ways to feel better, this study might be a good fit.
Porto Alegre, Rio Grande do SulAges 40–65 - NCT06481072Recruiting
Digital therapy for kids with chronic stomach pain
This trial tests a digital (online) therapy program to help children with chronic stomach pain. It's designed for kids ages 8 to 14 who have been diagnosed with a functional abdominal pain disorder and can use a computer or tablet at home.
GothenburgAges 8–14 - NCT04196595Recruiting
Apple study for women’s health using an iPhone app
This study looks at women’s health by collecting information through an Apple Research app on your iPhone. You may help improve how health data is gathered, while also checking in with the study team by agreeing to participate.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.