Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07791784Recruiting
Pain relief and shoulder exercises for shoulder pain
This study tests a program that combines pain management education with shoulder exercises to help people with long-lasting shoulder pain. The goal is to see if this approach reduces pain and improves daily function.
Ballerup MunicipalityAges 18–65 - NCT05566496Recruiting
MRI study of different tic disorder types
This study uses MRI (a type of body scan) to look at differences between types of tic disorders in children. It may help doctors better understand what’s happening in conditions like Tourette syndrome and chronic tic disorders.
TaipeiAges birth–18 years - NCT07790328Recruiting
Long-term safety of the IntraSPINE implant for low back pain
This study checks how safe and effective the IntraSPINE implant is over time for people with low back pain from degenerative discs. The implant is placed in your spine to support it, and this trial helps see if it continues working well for years.
SaranAges 18 years+ - NCT06536959RecruitingPhase 2
VA plus PD-1 inhibitor for relapsed AML and high-risk MDS
This trial tests a combination of two drugs—a chemotherapy-like agent called VA and a PD-1 inhibitor (which helps your immune system fight cancer)—for people with AML or high-risk MDS that has not responded to or returned after initial treatment. The goal is to see if this combination can work better than standard treatments alone.
Beijing, Beijing MunicipalityAges 18–70 - NCT05566392Recruiting
Studying long-term recovery in children after COVID-19
This study looks at how long “long COVID” affects children over time. It may help doctors better understand what symptoms last and what support could improve recovery.
TaipeiAges 6–18 - NCT04937699RecruitingPhase 4
Switching anti-platelet tablets after a heart stent
This trial studies whether changing the timing and type of blood-thinner tablets after a heart stent is as safe and effective as continuing the same plan. It may help some people by simplifying treatment while preventing dangerous clotting after a coronary procedure.
Hangzhou, ZhejiangAges 18–80 - NCT06541626Recruiting
Study of CNS inflammatory demyelinating diseases
This study follows people with certain inflammatory conditions of the brain and spinal cord (like MS, NMOSD, or MOGAD) to learn more about their disease. If you join, you will help researchers understand these conditions better.
Guangzhou, GuangdongAges 18–65 - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT07775976Enrolling by invitation
Whole-heart checkup with a wearable heart monitor
This study looks at how well a wearable heart monitor and special software can check the health of your whole heart and assess your risk of future heart problems. It may help doctors create more personalized care plans.
Pasadena, CaliforniaAges 18 years+ - NCT06550713RecruitingPhase 1
Testing TQB3455 tablets for blood cancers with IDH2 mutation
This trial tests a new tablet, TQB3455, for people with certain blood cancers (MDS or AML) that have an IDH2 mutation. The goal is to see if the drug can help when other treatments haven't worked or aren't possible.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07781540Recruiting
Iron deficiency at ICU discharge
This study checks if patients leaving the ICU have low iron levels. It may help doctors understand and treat iron deficiency after a serious illness.
BrusselsAges 18 years+ - NCT07777081Recruiting
How your brain and body recover after a wrist fracture
This study looks at how your brain and body heal after a wrist fracture. By joining, you'll help doctors understand recovery better, which could improve care for future patients.
Cambridge, CambridgeshireAges 18 years+ - NCT06555237RecruitingPhase 2
MEK inhibitors for heart thickening in RASopathies
This trial tests a targeted drug (MEK inhibitor) to treat thickened heart muscle caused by a group of genetic conditions called RASopathies. It may help improve heart function in people with hypertrophic cardiomyopathy.
WarsawAges 1 day–18 years - NCT06553339RecruitingPhase 1
A study of HS-10516 for VHL syndrome tumors
This trial tests a new drug called HS-10516 in people with VHL syndrome or advanced kidney cancer. The goal is to see if the drug can shrink tumors and what side effects it might have.
Beijing, Beijing MunicipalityAges 18–80 - NCT06212492Recruiting
Muscle relaxants and stomach positioning for ARDS
This trial tests whether combining two treatments—medications that relax muscles (neuromuscular blocking agents) and lying on your stomach (prone positioning)—can reduce lung damage in people with severe ARDS on a breathing machine.
MarseilleAges 18 years+ - NCT07771335Recruiting
Erlangen stroke registry: tracking strokes over time
This study collects health information from people in Erlangen, Germany who have had a stroke. It helps researchers understand stroke causes and outcomes to improve future care.
ErlangenAges 18 years+ - NCT06566066Recruiting
Thyroid hormone resistance patient registry
This study creates a registry for people with thyroid hormone resistance caused by specific genetic mutations. It helps doctors collect data to better understand and treat the condition.
BerlinAges Any age - NCT07761533RecruitingPhase 1/Phase 2
PBSS1113 plus azacitidine for blood cancers
This study tests a new drug (PBSS1113) combined with azacitidine for people with certain blood cancers (AML or high-risk MDS). The goal is to see if the combination is safe and effective.
Hangzhou, ZhejiangAges 18 years+ - NCT07764328Recruiting
Supplement for hormone balance in women with PCOS
This trial tests a dietary supplement designed to improve hormone balance in women with PCOS or PCOS-like symptoms. It may help regulate menstrual cycles and reduce signs like acne or excess hair growth.
Los Angeles, CaliforniaAges 18–40 - NCT06450327Recruiting
Resistant Hypertension: A Complex Condition Study
This study looks at why some people with hard-to-control high blood pressure (resistant hypertension) may also have other health problems. It aims to better understand the condition and how to help patients like you.
Votuporanga, São PauloAges 18–85 - NCT07763054Recruiting
Low-dose antifungal prevention for patients with low white blood cell counts
This trial tests a low dose of an antifungal medicine (liposomal amphotericin B) to prevent fungal infections in patients whose white blood cell counts are very low for more than a week. It may help patients who are at high risk for fungal infections and cannot take other antifungal drugs.
Hainan, HainanAges 18–75 - NCT07762222Recruiting
Iliac vein stenting for chronic post-thrombotic venous ulcers
This trial tests whether placing a stent (a small mesh tube) in the iliac vein can help heal chronic leg ulcers caused by prior blood clots. The goal is to improve blood flow and reduce symptoms.
CairoAges 18–70 - NCT07762144Enrolling by invitation
Recovery after cardiac arrest
This trial collects health information from people who have survived a cardiac arrest (when the heart stops) and have been brought back to life. The information may help doctors improve care and recovery after this event.
Beijing, Beijing MunicipalityAges Any age - NCT07762170RecruitingPhase 4
Steroid injections for back and pelvic pain
This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.
Thornhill, OntarioAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.