Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07165717Recruiting
Real-world study of breathing emergencies in ICU patients
This study looks at why some patients develop severe breathing problems in the ICU. It focuses on people who already have conditions like severe infections, injuries, or heavy bleeding that can stress the lungs.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07169058Enrolling by invitation
Hands-on therapy for sleep apnea: a gentle technique
This study tests a gentle manual therapy applied to the neck to see if it can improve breathing and vital signs during sleep. It is for people with moderate to severe sleep apnea who are not currently using a CPAP machine or other breathing devices.
Mardin, MardinAges 18–65 - NCT07167537RecruitingPhase 1
Study of OL-CD19-GDT for hard-to-treat autoimmune diseases
This trial tests a new treatment called OL-CD19-GDT for people with systemic sclerosis or Sjögren's syndrome that hasn't responded to standard therapies. It aims to see if the treatment is safe and might help control the disease.
BeijingAges 18–65 - NCT07166536Recruiting
Study on mental imagery and symptom worsening after concussion
This trial tests whether mental imagery tasks can trigger or worsen headaches and dizziness in people with long-lasting symptoms after a mild traumatic brain injury or concussion. If you still have headaches or dizziness more than 3 months after your injury, this study may help understand how your brain reacts to mental exercises.
Tel AvivAges 18–74 - NCT07166432Recruiting
New brain stimulation for thinking and balance problems in Cushing syndrome
This trial tests a new, minimally invasive brain stimulation technique for people with Cushing syndrome who have developed a condition called cerebellar cognitive affective syndrome (CCAS). It aims to improve both thinking skills and movement coordination.
BeijingAges 18–85 - NCT07168122Recruiting
Salivary cortisol test for adrenal health
This study is building a reference range for a simple saliva test that measures cortisol, a hormone linked to stress and adrenal function. It may help diagnose conditions like Cushing's syndrome or adrenal insufficiency.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07171970Recruiting
IVM vs IVF for women with PCOS
This trial compares two fertility treatments for women with PCOS: in vitro maturation (IVM) with fresh embryo transfer versus standard IVF with frozen embryo transfer. It aims to find which approach leads to better outcomes.
Ho Chi Minh CityAges 18–42 - NCT07167329RecruitingPhase 2
Belzutifan for VHL syndrome: a real-world study
This trial tests the drug belzutifan (a pill taken by mouth) in people with VHL syndrome who have kidney or other VHL-related tumors that are growing or can be measured. The study looks at how well belzutifan works in real-world conditions and whether certain genetic factors affect how the drug works.
São Paulo, São PauloAges 14 years+ - NCT07171905RecruitingPhase 2
Study of a new imaging agent for Von Hippel-Lindau disease
This trial tests a special imaging agent that targets a protein found in tumors related to Von Hippel-Lindau (VHL) disease. It may help doctors better detect and monitor these tumors.
Milan, ItaliaAges 18 years+ - NCT07171450Recruiting
Thinking skills training for older adults after COVID-19
This study tests a computer-based program to help improve memory and thinking in older adults who have ongoing cognitive problems after COVID-19. You may qualify if you are 60 or older and have had lasting thinking concerns since your infection.
Farmington, ConnecticutAges 60 years+ - NCT07171710Enrolling by invitation
Cyclosporine eye drops and tear duct plugs for dry eye in Sjögren's
This trial tests if using special eye drops (cyclosporine) along with tiny plugs placed in the tear ducts can improve dry eye symptoms in people with Sjögren's syndrome. The goal is to see if this combination works better than the drops alone.
Tianjin, Tianjin MunicipalityAges Any age - NCT07169487RecruitingPhase 1
Methylene Blue for Side Effects of Cancer Immunotherapy
This trial tests if methylene blue can help people who develop side effects called CRS or ICANS after treatments like CAR-T cells or bispecific antibodies. It is a first-in-human study to find a safe dose.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06382844Recruiting
Better detection of tumor cells in cutaneous T-cell lymphoma
This study uses advanced blood tests (flow cytometry) to find cancer cells more accurately in people with cutaneous T-cell lymphoma. It could lead to better monitoring of your condition.
SalamancaAges 18 years+ - NCT07157670Recruiting
Heart health study after stem cell transplant
This study looks at heart problems that can happen after a stem cell transplant from a donor (allogeneic). It aims to understand these risks better so doctors can help patients stay healthier after transplant.
ParisAges 15 years+ - NCT07159880Recruiting
Letrozole for ovulation induction in PCOS
This trial tests a longer course of letrozole to help women with PCOS ovulate and get pregnant. The goal is to see if extended therapy works better than the standard treatment.
São Paulo, São PauloAges 18–40 - NCT07164638Enrolling by invitation
Predicting fluid overload during prostate surgery
This study uses ultrasound to check for fluid overload in men having prostate surgery with spinal anesthesia. The goal is to see which ultrasound method works best to prevent complications.
TantaAges Any age - NCT07162285Enrolling by invitation
Bubble CPAP for Preterm Babies with Breathing Problems
This trial tests a special breathing support called bubble CPAP, given right after birth in the delivery room, to help preterm babies (born before 34 weeks) who are having trouble breathing. It aims to see if starting this treatment early can improve their breathing and health.
DhakaAges 5 minutes–30 minutes - NCT07155473Recruiting
Measuring fat in the pancreas
This study aims to create a score to measure fat inside the pancreas using imaging. It may help understand how pancreatic fat relates to health conditions.
Roma, RomeAges 18–80 - NCT07156214Recruiting
Understanding RFC1-ataxia to find biomarkers
This study looks at a rare genetic condition called RFC1-ataxia (also known as CANVAS). It aims to find better ways to diagnose and track the disease. You may qualify if you have this condition, are between 18 and 80, and can agree to take part.
BolognaAges 18–80 - NCT07157319Recruiting
Zadek osteotomy for Haglund's syndrome
This trial tests a surgery called Zadek osteotomy for people with Haglund's syndrome (a painful heel condition). It may help those who haven't gotten better after at least six months of non-surgical treatments.
SohagAges 18–60 - NCT07155226RecruitingPhase 1/Phase 2
Study of AZD3632 for advanced blood cancers with certain gene changes
This trial is testing a new drug, AZD3632, either alone or with other cancer treatments, for people with advanced blood cancers that have specific genetic changes (like KMT2Ar, NPM1m, or others that cause HOX over-expression). The goal is to see if it can help when standard treatments have stopped working.
Decatur, IllinoisAges 16 years+ - NCT07149519Recruiting
Diet and probiotics for endometriosis and IBS
This study tests whether dietary guidance and probiotics can help women with endometriosis and irritable bowel syndrome (IBS). It aims to see if these treatments improve symptoms and quality of life.
Catanduva, São PauloAges 15–50 - NCT07147933Recruiting
Treatment for crouch gait in cerebral palsy
This trial tests a treatment for children with cerebral palsy who have a crouched walking pattern, a forward-tilted pelvis, and weak calf muscles. It uses EMG to check muscle activity and aims to improve walking.
AmmanAges 4–10 - NCT07155070RecruitingPhase 4
Can eye drops help LASIK recovery?
This trial tests if Kera Sol Tears eye drops can reduce eye discomfort after LASIK surgery. If you are planning to have LASIK, this study may help you feel better during recovery.
Sioux Falls, South DakotaAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.