Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07195071Recruiting
Combining pregnancy carrier and cancer risk screening
This study combines routine obstetrical carrier screening with hereditary cancer risk screening in one blood draw. It aims to see if offering both tests together is feasible and helpful for patients receiving OB care.
New York, New YorkAges 18–55 - NCT07197138Recruiting
TMS for depression with long COVID
This trial tests whether accelerated TMS (a brain stimulation treatment) can help people with depression who also have long COVID. It may be an option if your depression hasn't improved enough with medication alone.
Munich, BavariaAges 18–65 - NCT07197255Recruiting
Gene study of cumulus cells in CAPA-IVM for PCOS patients
This study looks at gene activity in cumulus cells (cells that surround the egg) during a special type of in vitro maturation (CAPA-IVM) for women with polycystic ovary syndrome (PCOS). It may help doctors better understand how to improve this treatment for women with PCOS.
Ho Chi Minh CityAges 18–38 - NCT06939985Recruiting
Heart health and metabolism registry for heart failure
This trial is a registry that will follow people with different types of chronic heart failure to better understand how heart health and metabolism are linked. It may help doctors improve care for future patients.
ShanghaiAges 18 years+ - NCT07184450RecruitingPhase 1
CAR-T cell therapy for children with hard-to-treat rheumatic diseases
This trial tests a new treatment using your child's own immune cells, modified to target B cells and fight severe rheumatic diseases like juvenile dermatomyositis, arthritis, scleroderma, or Sjogren's syndrome. It's for children who haven't improved with standard treatments.
Hangzhou, ZhejiangAges 5 years+ - NCT07188038Recruiting
Comparing low vs high breathing tube pressure on diaphragm health
This trial compares two levels of positive end-expiratory pressure (PEEP) in patients on a breathing machine. It looks at how these pressures affect diaphragm function, how well the lungs work, and how efficiently you breathe.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT06944743Recruiting
Prostate surgery for men with underactive bladder and blockage
This study tests a prostate surgery (TURP) in men with two bladder problems: a blockage leaving the bladder and a bladder that doesn't contract well. The goal is to see if the surgery can help improve bladder emptying.
SohagAges 40–70 - NCT07186179Recruiting
Stem cell mobilization for diamond blackfan anemia
This trial tests whether a medication can help move your own blood stem cells from your bone marrow into your bloodstream, so they can be collected. This is a first step toward possibly using those cells in a future treatment for diamond blackfan anemia.
New Hyde Park, New YorkAges 3–30 - NCT07188285Enrolling by invitation
Immune system study for active autoimmune diseases
This study uses a blood test called mass spectrometry to look at the immune system in people with active autoimmune diseases. It aims to find patterns that could help doctors better understand and treat these conditions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07192965Recruiting
Heart scan without ECG for chest pain with high troponin
This trial tests if a coronary CT scan (without needing an ECG) can safely guide care for people who come to the emergency room with chest pain and a high troponin level. It aims to see if this approach works as well as standard tests.
JetteAges 30 years+ - NCT07189234RecruitingPhase 2
Time-restricted eating for better heart health
This trial tests if eating all your meals within a shorter window each day can improve blood sugar, blood pressure, and cholesterol. You may qualify if you have prediabetes or metabolic syndrome and eat over 12 hours daily.
La Jolla, CaliforniaAges 18–75 - NCT07184307Recruiting
Platelet-rich plasma vs botox for stubborn overactive bladder
This trial compares two treatments for overactive bladder (OAB) that hasn't improved with standard medications: injections of platelet-rich plasma (a substance from your own blood) versus botulinum toxin (Botox). Both are injected into the bladder to help reduce urgency and leakage.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07190690Recruiting
Comparing two drug-coated stents for heart attack patients
This trial compares two types of drug-coated stents (one with sirolimus, one with everolimus) in people who have had a heart attack or unstable angina and need a stent. It aims to see which stent works better for new blockages in the heart arteries.
AlicanteAges 18 years+ - NCT06936618Recruiting
Electrical impedance guided ventilator settings for breathing failure
This trial tests whether using electrical impedance tomography (EIT), a safe and non-invasive monitoring technique, helps doctors set the ventilator better for patients with low oxygen levels. It may improve your breathing support during mechanical ventilation.
BangkokAges 18 years+ - NCT05011331Recruiting
Custom pillow study for better shoulder-area sleep
This trial tests whether a specially made pillow can help people with rotator cuff problems sleep better without surgery. You would use the pillow and answer questions about your sleep quality.
East Providence, Rhode IslandAges 18 years+ - NCT05257629RecruitingPhase 3
Aggressive smoking quit program after heart problems
This trial tests whether a strong quit plan using varenicline (a quit pill) plus nicotine e-cigarettes, along with counseling, helps people stop smoking after a recent heart-related event. It’s aimed at people who want to quit and can safely stay involved for about a year.
New Westminster, British ColumbiaAges 18 years+ - NCT07182175Enrolling by invitation
Heart health during adrenal tumor surgery study
This study looks at how different types of adrenal tumors might affect the heart during and after surgery. It aims to help doctors understand and reduce the risk of heart injury in patients having these tumors removed.
BeijingAges 18 years+ - NCT07176117Enrolling by invitation
Surfactant via airway device for breathing trouble in newborns
This trial tests if giving surfactant (a natural substance that helps lungs stay open) through a special airway device can help late preterm and early term infants with breathing problems. The goal is to see if this approach works better than current methods without needing a breathing tube.
Chula Vista, CaliforniaAges 8 months–9 months - NCT07180407Recruiting
Post-ICU pain study for adults
This study looks at pain after a stay in the intensive care unit (ICU). It aims to understand pain in patients who were urgently admitted to the ICU and stayed for at least two days.
AalborgAges 18 years+ - NCT07180537Recruiting
Health course for joint and mood conditions
This study tests an online health course that helps improve diet and self-care to support cell health and wellbeing. It is for people with certain rheumatological conditions like rheumatoid arthritis, lupus, or psoriatic arthritis, who also have mood concerns.
Iowa City, IowaAges 18–100 - NCT07175493RecruitingPhase 1/Phase 2
CM336 for relapsed or refractory autoimmune cytopenia
This study tests a new drug called CM336 for people whose immune system mistakenly attacks their own blood cells (autoimmune cytopenia) and hasn't been controlled by other treatments. The goal is to see if CM336 can safely help improve blood cell counts.
Zhengzhou, HenanAges 18 years+ - NCT07176923RecruitingEarly Phase 1
Gene editing for familial chylomicronemia syndrome (FCS)
This study tests a new gene-editing treatment called CS-121 for people with FCS whose triglycerides remain very high despite standard therapy. It aims to lower triglyceride levels by editing the APOC3 gene.
Hefei, AnhuiAges 18–55 - NCT04644042Recruiting
Surgery for shoulder pain after non-surgical treatment fails
This trial looks at whether arthroscopic subacromial decompression surgery helps people whose “impingement” shoulder pain hasn’t improved after supervised exercises and an injection. It may help if your symptoms match their specific non-responder pattern and you can complete rehab visits.
Hvidovre, DenmarkAges 18–99 - NCT04142307Recruiting
Biofeedback training for infant eye shaking
This trial tests whether biofeedback-based training can improve control of eye shaking (nystagmus) in infants with idiopathic infantile nystagmus. If you can safely follow the training and testing steps, it may help the eyes learn more steady viewing over time.
Toronto, OntarioAges 5–17
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.