Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05981664Recruiting
Can adaptive gaming help kids with arm differences?
This study explores whether playing video games with adapted controls can help children aged 7 to 17 who have a missing or different arm or hand. It tests how fun and useful these games are for improving movement and daily life.
Winnipeg, ManitobaAges 7–17 - NCT05983952RecruitingPhase 2
Anti-CD38 antibody for APS with low platelets
This trial tests an anti-CD38 antibody in people with antiphospholipid syndrome (APS) who have very low platelet counts and haven't improved with steroids or other treatments. The goal is to see if it can safely raise platelet levels.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05984069Recruiting
Fatigue and frailty after ICU stay
This study looks at how feeling weak or frail after an ICU stay affects tiredness. It aims to find better ways to help people recover from serious illness.
Saint-EtienneAges 18 years+ - NCT05986240RecruitingPhase 1
Danvatirsen with or without venetoclax for advanced MDS or AML
This trial tests a new drug called danvatirsen, first alone and then combined with venetoclax, for people with advanced myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) that has come back or not responded to treatment. It aims to see if this approach can help when other options have stopped working.
The Bronx, New YorkAges 18 years+ - NCT05987124RecruitingPhase 2
Higher dose defibrotide for SOS after stem cell transplant
This study tests whether a higher dose of defibrotide can help patients who develop SOS/VOD after a stem cell transplant and haven't gotten better with the standard dose. SOS/VOD is a liver condition that sometimes also affects the kidneys or lungs.
Vallhala, New YorkAges 1 month–75 years - NCT05991908RecruitingPhase 3
Comparing chemotherapy regimens before stem cell transplant for blood cancers
This trial is testing two different chemotherapy regimens (with one or two alkylating agents) before a stem cell transplant for people with acute myeloid leukemia or myelodysplastic syndrome. The goal is to find which conditioning treatment is safer and more effective.
Fuzhou, FujianAges 16–55 - NCT05992311RecruitingPhase 1
Testing montelukast for gulf war illness
This study tests whether montelukast, a medication for asthma and allergies, can help improve thinking problems in veterans with Gulf War Illness. The trial involves taking the study drug or a placebo for 8 weeks, with weekly phone check-ins.
Houston, TexasAges 50–70 - NCT05993754Recruiting
Preventing confusion after surgery in frail older adults
This study tests whether a special nursing care plan can help prevent confusion after surgery in older adults who are frail. If you are 65 or older, having planned surgery, and generally healthy enough, this trial may be an option.
Santiago, Santiago MetropolitanAges 65 years+ - NCT05996731Recruiting
Using RNA tests to help diagnose rare genetic diseases
This study uses RNA sequencing to find genetic causes of rare diseases that standard DNA tests might miss. It may help people who have symptoms of a rare disease but no clear genetic diagnosis yet.
Ranica, BGAges Any age - NCT06001645Recruiting
Lung biomarkers and air leaks in severe lung injury
This study looks for markers in the blood and signs of air trapped in the lung tissue of people with acute respiratory distress syndrome (ARDS). It uses CT scans to understand why air leaks happen and if certain lab tests can predict them.
CagliariAges 18 years+ - NCT06003686Recruiting
Spinal cord injury education study for adults
This study is looking at how well a special education program helps people with spinal cord injuries manage their health and daily life after leaving the hospital. It is for adults who recently finished their first rehabilitation stay and have a spinal cord injury from the C5 level or lower.
Washington D.C., District of ColumbiaAges 18–70 - NCT06005246Recruiting
Munich ME/CFS Study for Young People
This study is tracking children, teens, and young adults (up to age 25) who developed ME/CFS after an infection. It aims to better understand the condition in younger people.
Munich, BavariaAges Up to 25 years - NCT06007547RecruitingPhase 4
Preventive surfactant therapy for preterm babies
This trial tests whether giving surfactant (a foam that helps lungs stay open) before breathing problems start can help very premature babies (born before 30 weeks) breathe better. It might reduce the need for a breathing tube.
Evanston, IllinoisAges Up to 15 minutes - NCT06008808RecruitingPhase 1
Ruxolitinib and abatacept to prevent GVHD after haplo transplant
This trial tests whether a drug called ruxolitinib, with or without another drug called abatacept, can prevent graft-versus-host disease and cytokine release syndrome after a half-matched stem cell transplant from a family donor. It's for people with certain blood cancers who are getting this type of transplant.
St Louis, MissouriAges 18 years+ - NCT06012903Recruiting
Bladder symptoms and school performance in children
This study looks at how lower urinary tract symptoms (like frequent bathroom trips or accidents) affect children's daily life and schoolwork. It aims to understand these challenges from the child's, parent's, and teacher's point of view.
Ghent, East FlandersAges 5–12 - NCT06013423RecruitingPhase 2
Cord blood transplant with chemo and radiation for high-risk blood cancers
This trial tests a cord blood transplant after a reduced-intensity chemotherapy and radiation regimen for patients with high-risk blood cancers like leukemia, lymphoma, or MDS. The goal is to see if this approach can help destroy cancer cells and restore healthy blood cells.
Seattle, WashingtonAges 6 months–65 years - NCT06014112Recruiting
Glucose monitor test for heart attack recovery
This study tests a continuous glucose monitor (FSL Pro iQ) in people with heart attack to see if blood sugar patterns can predict recovery. It may help doctors better manage your care after a heart attack.
BéziersAges 18–85 - NCT06022549Recruiting
Mobile health for HIV patients with metabolic and bone issues
This trial tests a mobile health program designed to help people with HIV manage metabolic syndrome and bone loss. It aims to find if text messages and health tips can improve your health.
TaipeiAges 30 years+ - NCT06031324Recruiting
Lung ultrasound to predict recovery in newborns with breathing trouble
This study looks at whether a lung ultrasound (a safe, painless scan) can help predict how well a newborn will recover from breathing problems that start right after birth. It may help doctors decide on the best care more quickly.
BursaAges 30 minutes–2 hours - NCT06034275RecruitingPhase 1
Study of VIP943 for CD123-positive blood cancers
This trial tests a new drug called VIP943 for people with advanced acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia (B-ALL), or myelodysplastic syndrome (MDS) whose cancer cells have a marker called CD123. It is for those who have tried all other treatments or cannot receive them.
Birmingham, AlabamaAges 18 years+ - NCT06037330RecruitingPhase 4
Study of nalbuphine for ARDS after surgery
This trial tests if the drug nalbuphine can help patients with acute respiratory distress syndrome (ARDS) after surgery. It aims to see if it improves breathing and pain while staying in the ICU.
Jinan, ShandongAges 18 years+ - NCT06040567Recruiting
Polyneuropathy, Impairments and Physical Activity Study
This study looks at how polyneuropathy (nerve damage) affects your daily physical activity and overall function. It aims to understand the link between nerve damage and movement, which could help improve care.
CopenhagenAges 18–100 - NCT06046313RecruitingPhase 2
Low-dose decitabine plus venetoclax for older AML/MDS
This trial tests a combination of two drugs (decitabine and venetoclax) at a very low, extended dose for people aged 60 or older who have been newly diagnosed with acute myeloid leukemia or high-risk myelodysplastic syndrome. The goal is to see if this gentler approach is effective and well-tolerated.
Hangzhou, ZhejiangAges 60 years+ - NCT06047886RecruitingPhase 1
Study of a new way to select stem cells for transplant
This trial tests a machine that picks out healthy stem cells for a bone marrow transplant. It may help people with certain blood cancers or disorders get a transplant with fewer complications.
Birmingham, AlabamaAges 4 weeks–75 years
Hear when a new Down Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.