Clinical trials
Dry Eye Disease (DED) clinical trials
Below are recruiting dry eye disease (ded) clinical trials, each written for real people, not researchers. We’re tracking 38 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07266948RecruitingPhase 4
How TRYPTYR eye drops affect dry eye symptoms and daily life
This study tests a new eye drop called TRYPTYR to see if it can improve quality of life and daily tasks for people with dry eye disease who are unhappy with their current treatment, Restasis. Participants will stop using Restasis and switch to TRYPTYR for about 4 weeks.
Pittsburg, KansasAges 18–75 - NCT07268599Enrolling by invitation
Acoltremon for moderate-to-severe dry eye relief
This study tests a new eye drop called Acoltremon to see if it can relieve symptoms of moderate-to-severe dry eye disease. It may be a good option if you have had dry eye for at least 6 months and use artificial tears.
Encino, CaliforniaAges 18–60 - NCT07155057Recruiting
Dry eye gel for cataract surgery patients
This study tests a gel placed into the tear drain to treat dry eye in people who are also getting cataract surgery. You may be able to join if you have dry eye and are having cataract surgery.
Sioux Falls, South DakotaAges 22 years+ - NCT06984549Recruiting
Dry eye detection via smartphone camera
This study tests if a smartphone can take clear pictures and videos of your eyes to help doctors check for dry eye disease. It may be a simpler way to evaluate dryness from home.
Wenzhou, ZhejiangAges 18 years+ - NCT06898853Recruiting
Eye drops for dry eye: A 12-week study
This trial tests whether an anti-inflammatory eye drop (ciclosporin A) can help dry eyes by changing immune cells on the eye's surface. It lasts 12 weeks and may be an option for people with moderate to severe dry eye.
Sydney, New South WalesAges 18 years+ - NCT06860659Enrolling by invitationPhase 4
Hyaluronate eye drops for moderate to severe dry eye
This trial tests whether 0.28% sodium hyaluronate eye drops can help people with moderate to severe dry eye feel better. It's for patients who have significant dry eye symptoms and signs on an eye exam.
Bangkok, BangkokAges 18 years+ - NCT06655441RecruitingPhase 4
Trehalose eye drops for dry eye disease
This study tests if a special sugar-based eye drop called trehalose can improve the protective layer of the eye in people with moderate to severe dry eye. It might help strengthen the cornea and reduce discomfort.
Fullerton, CaliforniaAges 18 years+ - NCT06615453Recruiting
Tixel treatment for dry eye disease and periorbital wrinkles
This study tests a device called Tixel that may help reduce wrinkles around the eyes and improve dry eye symptoms. If you have mild to moderate under-eye wrinkles and dry eyes that bother you a lot, this treatment might be an option.
BirminghamAges 18 years+ - NCT05865379Recruiting
Tested eye drops for dry eye relief and safety
This trial studies whether BUFY01 eye drops work better than SVS20 for treating dry eye disease. You may be able to join if you have dry eye symptoms for at least 3 months and meet eye exam score and tear-test requirements.
LeuvenAges 18 years+ - NCT05865457Recruiting
Testing two eye treatments for dry eye symptoms
This trial compares two different dry-eye eye drops to see which works better and is safe. You may be able to join if you’ve had dry eye for at least 3 months and meet specific eye-test results.
GrazAges 18 years+ - NCT07606625RecruitingPhase 4
Nasal spray for dry eye disease and tear film stability
This study tests whether a nasal spray can improve dry eye symptoms and tear production in people with mild to moderate meibomian gland dysfunction (a common cause of dry eye). You'll use the spray daily while the research team monitors your eye health and comfort over several weeks.
Berkeley, CaliforniaAges 18 years+ - NCT07790211RecruitingPhase 4
Eye drop for tear film stability
This study tests an eye drop to help stabilize the natural tear film on the surface of the eye. It may help people who have normal tear production but could benefit from better tear film stability.
Sioux Falls, South DakotaAges 18 years+ - NCT07705893Recruiting
Treating contact lens discomfort with a nasal spray
This trial tests a nasal spray (varenicline) to see if it can relieve discomfort and dryness from contact lens wear. If you wear daily disposable soft contacts and experience end-of-day eye dryness, you may be eligible.
Houston, TexasAges 18–99 - NCT07277257RecruitingPhase 4
New dry eye treatment for people with Sjögren's syndrome
This study tests a new treatment for dry eye disease caused by Sjögren's syndrome. It may help people who still have dry eye symptoms even when using artificial tears.
Venice, FloridaAges 18 years+
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Common questions
- Are there clinical trials for dry eye disease (ded)?
- Yes. Clin2 currently lists 38 recruiting dry eye disease (ded) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dry eye disease (ded) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dry eye disease (ded) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.