Clinical trials
Dystonia clinical trials
Below are recruiting dystonia clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06937931RecruitingPhase 2
Study of IPN10200 for neck muscle spasms in adults
This trial tests a new botulinum toxin medication (IPN10200) for adults with cervical dystonia, a condition that causes painful muscle spasms in the neck and shoulders. It aims to see if the treatment is safe and effective in reducing symptoms.
Tucson, ArizonaAges 18–80 - NCT06881147Enrolling by invitation
Physiotherapy and Botox for Neck Dystonia
This study tests whether combining physiotherapy with Botox injections can improve neck control in people with cervical dystonia. It also looks at how 'sensory tricks' (like touching your face) help the brain control symptoms, using brain scans to understand why.
Milan, ItaliaAges Any age - NCT06830174Recruiting
tDCS Brain Stimulation for Laryngeal Dystonia
This study tests whether a gentle brain stimulation technique called tDCS can help improve voice control in people with laryngeal dystonia. It aims to find a new way to reduce muscle spasms in the voice box.
New Haven, ConnecticutAges 18–65 - NCT06771323RecruitingPhase 2
Adding valbenazine to botox for neck muscle spasms
This study tests if adding a daily pill (valbenazine) to regular botox injections can better reduce neck muscle spasms. It helps people whose botox works but may not be enough.
Richmond, VirginiaAges 18–75 - NCT05663840Recruiting
Exercise program study for focal neck dystonia
This trial tests how a structured exercise program affects the brain and body changes behind focal cervical dystonia (a movement disorder that causes abnormal neck postures). It may help people who are still having symptoms despite best-available treatments like botulinum toxin injections or medicines.
Gainesville, FloridaAges 30–85 - NCT06554288RecruitingPhase 1
Trihexyphenidyl for dystonia in cerebral palsy
This study tests how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy, a condition that causes muscle spasms. Researchers want to learn if a child’s genes affect how the medicine works and how the body processes it.
Kansas City, MissouriAges 5–17 - NCT05502718Recruiting
Exercise program for cervical dystonia treated with botulinum toxin
This trial studies whether a structured exercise program can help people with cervical dystonia (involuntary neck muscle tightening) who are already being treated with botulinum toxin type A. It may help improve how you move and function, alongside your usual injections.
Ankara, AltındağAges 18 years+ - NCT06367608Recruiting
Focused ultrasound for task-specific hand dystonia
This trial tests a new way to treat severe hand cramps that happen only when you do a specific task (like writing or playing an instrument). It uses focused ultrasound to precisely target a small area in the brain to calm the unwanted movements.
Baltimore, MarylandAges 21–75 - NCT06328114Enrolling by invitationPhase 2
Brain stimulation for cervical dystonia
This study tests a type of brain stimulation called TMS to see if it can improve neck muscle spasms in people with cervical dystonia. It's for adults who haven't had Botox recently and are not on other treatments.
Durham, North CarolinaAges 18 years+ - NCT05150106Recruiting
Study brain and voice patterns in laryngeal dystonia
This study looks at how the brain and voice system work in people with laryngeal dystonia or voice tremor, and compares them with healthy volunteers. The goal is to better describe different “types” (phenotypes) so future care can be more targeted.
Boston, MassachusettsAges 18–80 - NCT04421365Recruiting
Brain–computer interface study for voice spasms from laryngeal dystonia
This study tests how a brain–computer interface reads brain signals to understand and possibly support people with a specific voice condition called adductor laryngeal dystonia. It also compares results with healthy people to help researchers see how brain activity differs during voice tasks.
Boston, MassachusettsAges 18–80 - NCT05216770RecruitingEarly Phase 1
Brain-scan study of voice dystonia and tremor
This early study uses brain and voice-related testing to better understand what is happening in the brain in people with laryngeal dystonia or voice tremor. The results may help scientists learn more about these conditions and how they differ from healthy voices.
Boston, MassachusettsAges 18–80 - NCT03977493RecruitingPhase 3
Xeomin injections for focal hand muscle spasms
This trial tests incobotulinumtoxinA (Xeomin) injections to reduce focal hand dystonia—unwanted muscle tightening in the hand. You may be able to join whether you’ve had this condition before or have tried similar injections in the past, as long as certain safety rules are met.
BernAges 18 years+ - NCT02686125Recruiting
Study of the Vercise brain stimulator for dystonia
This study looks at how well a specific implanted brain stimulator (the Vercise system) works for people with dystonia. It may help confirm whether the device improves symptoms and is safe for eligible patients.
GhentAges 7 years+ - NCT03992625Recruiting
Deep brain stimulation study for Parkinson’s, tremor, or dystonia
This trial studies outcomes after deep brain stimulation (a treatment that uses implanted electrodes) for people with Parkinson’s disease, essential tremor, or dystonia. It may help doctors understand who benefits most and how outcomes change after treatment.
St Louis, MissouriAges Any age - NCT07868614Recruiting
Comparing brain signal recordings during deep brain stimulation surgery
This study compares a new device for recording brain signals during deep brain stimulation (DBS) surgery with the standard equipment. DBS is a treatment for movement disorders like Parkinson's disease that uses a device to send electrical signals to specific parts of the brain.
Rochester, MinnesotaAges 18 years+ - NCT06566066Recruiting
Thyroid hormone resistance patient registry
This study creates a registry for people with thyroid hormone resistance caused by specific genetic mutations. It helps doctors collect data to better understand and treat the condition.
BerlinAges Any age - NCT06174948Recruiting
CUE1 device for Parkinson's and related movement disorders
This trial tests a small device called CUE1 that gives gentle vibrations on the chest to help improve movement and balance in people with Parkinson's disease and similar conditions. It may help if you have trouble with walking or stability.
LondonAges 18 years+ - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07190092Recruiting
Brain stimulation for post-stroke muscle stiffness and movement
This study tests a new type of brain stimulation (deep anterior cerebellar stimulation) to see if it can reduce muscle stiffness and improve movement in people who had a stroke 9–36 months ago and still have tightness or weakness that hasn't gotten better with therapy.
BydgoszczAges 18 years+ - NCT07167732Recruiting
CTNNB1 Syndrome Natural History Study
This study follows people with CTNNB1 syndrome over time to better understand the condition. It does not test any new treatment—just collects information to help future research.
SydneyAges Any age - NCT06967727Recruiting
Registry study for epilepsy and movement disorders
This study is creating a registry to track the health of people who have specific genetic changes that cause epilepsy and uncontrolled movements (dyskinesia). It may help researchers better understand these conditions and how they change over time.
Boston, MassachusettsAges birth–30 years - NCT06912841Enrolling by invitation
Deep brain stimulation for genetic movement disorders
This trial is for people of any age with a genetic movement disorder who are getting or considering deep brain stimulation (DBS). It tries to match the best DBS settings for each person.
Boston, MassachusettsAges Any age - NCT06899022Recruiting
Attention and eye movement in Parkinson's disease
This study looks at how attention and eye movements work in people with Parkinson's disease, essential tremor, or dystonia. It tests abilities during deep brain stimulation (DBS) surgery and when DBS settings are changed.
Omaha, NebraskaAges 19–90
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Common questions
- Are there clinical trials for dystonia?
- Yes. Clin2 currently lists 62 recruiting dystonia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dystonia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dystonia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.