Clinical trials
Edema clinical trials
Below are recruiting edema clinical trials, each written for real people, not researchers. We’re tracking 125 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06450392RecruitingPhase 4
Tranexamic acid for less swelling and bruising after eye socket surgery
This study tests whether giving tranexamic acid (a medicine that helps blood clot) locally or through an IV can reduce swelling and bruising after eye socket surgery.
The Bronx, New YorkAges 18 years+ - NCT06153277Recruiting
Does swelling affect TENS treatment after knee replacement?
This trial studies how swelling (edema) in the knee after replacement surgery might change the way a TENS machine works. TENS is a device that uses mild electrical pulses to help with pain. The results could help doctors set the right TENS level for each patient.
KaramanAges 40 years+ - NCT03161652RecruitingPhase 2
Levosulpiride for diabetic eye swelling and retinopathy
This Phase 2 study tests whether levosulpiride can improve changes in the retina in people with diabetic retinopathy and diabetic macular edema (eye swelling that can affect vision). It may help by targeting chemicals in the body that could affect eye tissue and inflammation.
Querétaro City, QuerétaroAges 40–69 - NCT04225611RecruitingPhase 1/Phase 2
Drug-delivering contact lens for recurrent macular swelling
This study tests a special contact lens that slowly delivers anti-inflammatory/steroid medicine to the back of the eye. It aims to treat cystoid macular edema that keeps coming back and may improve vision for people who respond to steroid treatment.
Boston, MassachusettsAges 18–85 - NCT05636579RecruitingPhase 1
Testing safety of multiple EO2002 eye drops for corneal swelling
This Phase 1 study tests whether EO2002 eye drops are safe and well tolerated in people with painful corneal swelling caused by the cornea’s inner lining not working well. It focuses on safety first, but your eye symptoms and vision may be monitored to see how you respond.
Mexico City, Mexico CityAges 18 years+ - NCT05505500Recruiting
Parent and patient interviews for childhood kidney swelling
This study uses interviews to understand how swelling from nephrotic syndrome affects daily life for children and their caregivers. It may help researchers design better care by capturing the patient and parent perspective.
Ann Arbor, MichiganAges 2 years+ - NCT05226247Recruiting
Check whether careful weaning prevents lung fluid buildup
This study looks at people on a breathing machine for more than 48 hours who are starting a “spontaneous breathing trial,” a test used to see if they can breathe on their own. It focuses on those at higher risk of “weaning-induced pulmonary edema,” meaning fluid can collect in the lungs during the weaning process.
DijonAges 18 years+ - NCT05142800Recruiting
Screening for Lymphedema in Breast Cancer Targeted Therapy
This study is looking at whether targeted therapy for breast cancer changes the risk of arm swelling (lymphedema). It is a screening trial that uses a machine to measure arm size and check for any swelling early on.
Boston, MassachusettsAges 18–80 - NCT04307615Recruiting
Oxygen versus CPAP during emergency lung fluid episodes
This trial tests whether regular oxygen or CPAP (a breathing-support machine) works better for people who have swimming-induced pulmonary edema, a sudden buildup of fluid in the lungs after swimming. It may help doctors choose the safest and most effective breathing treatment in an emergency.
FalunAges 18 years+ - NCT03999138Recruiting
MRI study of lung fluid changes in acute heart failure
This study uses MRI scans to measure lung fluid (pulmonary edema) in people hospitalized for acute heart failure. It aims to see how well the lung fluid responds to standard treatments like water pills (diuretics) given in the first couple of days.
Edmonton, AlbertaAges 18 years+ - NCT07592273RecruitingPhase 2/Phase 3
Gene therapy for diabetic eye disease without macular swelling
This trial tests a gene therapy injection into the eye to treat diabetic retinopathy (eye damage from diabetes) before it progresses. The goal is to slow or prevent vision loss and potentially delay the need for laser treatment or other injections.
Mesa, ArizonaAges 18 years+ - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT05072262RecruitingPhase 4
Topical anti-inflammatory eye drops after corneal transplant
This study tests whether anti-inflammatory eye drops (nepafenac, an NSAID) can help reduce swelling in the macula (the sharp-vision part of the eye) after certain cornea transplant surgeries. It compares outcomes in adults having DSAEK or DMEK who can safely use the study drops.
OsloAges 18 years+ - NCT04114799Recruiting
Tests brain-surgery monitoring to optimize circulation
This study checks a monitoring approach during brain tumor surgery to help control blood flow and heart-related measurements. It may benefit you by making surgery safer and helping the team respond faster during the operation.
Hradec KrálovéAges 18 years+ - NCT06492876RecruitingPhase 1/Phase 2
Gene therapy trial for diabetic macular edema (DME)
This trial tests a gene therapy for diabetic macular edema (DME), a condition where fluid builds up in the central part of the eye's retina. It aims to improve vision and reduce the need for frequent eye injections.
Tianjin, Tianjin,ChinaAges 18–74 - NCT07734844RecruitingPhase 3
New vs existing treatment for diabetic macular edema
This study compares a new medication, tabirafusp tedromer, to an existing treatment, aflibercept, for people with diabetic macular edema (swelling in the back of the eye from diabetes). It may help if your DME hasn't improved or you're looking for a new option.
Glendale, CaliforniaAges 18 years+ - NCT06697470Recruiting
Ultrasound and fluid monitoring in the ICU
This study uses ultrasound and electrical impedance (skin electrodes) to track fluid balance in the muscles and tissues of ICU patients. It aims to see if these tools can help doctors better manage fluids during your stay.
Boussu, HainautAges 18 years+ - NCT07626645Recruiting
Shock wave therapy for leg swelling from lymphedema
This trial tests whether extracorporeal shock wave therapy—a non-invasive treatment that uses sound waves—can help reduce swelling in the legs caused by lymphedema. You would receive this treatment while continuing your current compression therapy.
Ankara, YenimahalleAges 18–80 - NCT02669953Recruiting
Aflibercept injections for persistent wet macular degeneration
This trial studies whether aflibercept injections can help when “wet” age-related macular degeneration is recurring or not fully going away. It focuses on adults who have already had ranibizumab and still have measurable vision in the study eye.
ViennaAges 50 years+ - NCT07576036Enrolling by invitation
Study of severe low sodium and brain safety during treatment
This is a retrospective study (meaning researchers look back at medical records) of patients who had very low sodium levels in their blood when admitted to the hospital. Researchers want to understand the link between how quickly doctors correct low sodium and a rare brain condition called osmotic demyelination syndrome.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07567833RecruitingPhase 4
Tracking Eye Function After Diabetes Swelling Treatment
This study follows patients with diabetic eye swelling (a complication of diabetes affecting the macula, the part of your eye needed for detailed vision) who are receiving anti-VEGF injections—a standard treatment that reduces abnormal blood vessel growth. Researchers will measure how well your retina (the light-sensitive tissue in your eye) recovers and functions over time.
Augusta, GeorgiaAges 18 years+ - NCT07516964Recruiting
Studying autoimmune kidney disease in children and adults
This study collects medical information and samples from patients with podocytopathy—a type of autoimmune kidney disease that causes protein leakage into urine. Researchers will analyze your medical records and any blood or kidney tissue samples you've already had to better understand the disease and find better treatments.
Rochester, MinnesotaAges birth–99 years - NCT07520045Recruiting
Eye Injections for Diabetic Vision Loss: Two Treatment Comparison
This study compares two injectable medications (faricimab and biosimilar ranibizumab) used to treat diabetic retinopathy, a serious eye condition that can cause vision loss in people with diabetes. The trial will measure how well each medication works and track specific markers in your eye to understand treatment response.
OsijekAges 18 years+ - NCT07472543Recruiting
Virtual reality exercises for leg lymphedema after cancer surgery
This trial tests whether virtual reality-based exercises can help reduce leg swelling caused by lymphedema after gynecological or other cancer surgery. It may be a good option if you have lymphedema in one leg and can commit to daily sessions for a month.
AnkaraAges 18–65
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Common questions
- Are there clinical trials for edema?
- Yes. Clin2 currently lists 125 recruiting edema studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a edema trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a edema trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.