Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,875 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05024175Recruiting
Follow-up for people who received CAR T-cell therapy
This study is for people who previously received CAR T cells at the Dana-Farber/Harvard Cancer Center (DF/HCC). It mainly checks how you’re doing over the long term after treatment, and asks you to take part in follow-up visits or procedures.
Boston, MassachusettsAges 18 years+ - NCT04861818Recruiting
Testing how exercise timing affects memory in healthy young adults
This study looks at whether the time of day you exercise changes how well you remember things. It asks healthy young adults to do controlled exercise over two lab visits and avoids exercise for a few days to compare results.
Greensboro, North CarolinaAges 18–25 - NCT04781972RecruitingPhase 4
Brain scan study of ADHD effects from methylphenidate
This study uses brain imaging (MRI) to see how methylphenidate affects brain activity in people with ADHD. It may help doctors better understand how this medicine works and who benefits most.
Baltimore, MarylandAges 6–40 - NCT04742478Recruiting
Study of atherectomy and ultrasound for heavily calcified heart arteries
This study looks at how safe and effective a treatment is for heart artery blockages that are heavily hardened by calcium. It enrolls people who need a procedure to open the artery (with or without a stent) and whose blockage matches specific imaging or access problems.
KitakyushuAges 21 years+ - NCT04166071Enrolling by invitationEarly Phase 1
Testing whether opioids plus support change learning behavior
This early study tests how opioid medicine, along with social support, affects how people learn or “unlearn” certain responses. If you’re healthy and meet safety requirements, it may help researchers understand how support could change the effects of pain-related medicines on behavior.
Los Angeles, CaliforniaAges 18–35 - NCT03909477Recruiting
Study of MRI brain scans in cannabis smokers over time
This study follows people who currently or used to smoke cannabis to see how cannabis use may change certain MRI scan signals in the brain over time. You may help researchers understand the effects of cannabis smoking and how brain imaging changes can be measured safely.
London, OntarioAges 18–85 - NCT03384563RecruitingPhase 4
Testing a sedative’s effect on anesthesia dose needs in toddlers
This study looks at whether dexmedetomidine changes the minimum amount of sevoflurane (an inhaled anesthesia medicine) needed during surgery in young children. It may help doctors choose safer, more accurate anesthesia dosing for kids undergoing surgery.
Houston, TexasAges 1 month–3 years - NCT01629017Recruiting
Long-term follow-up after a stem cell transplant
This study looks at the long-term health effects of hematopoietic (blood-forming) stem cell transplants. It may help doctors better understand and manage late side effects for children and teens after transplant.
Stanford, CaliforniaAges Up to 18 years - NCT03887715RecruitingTeam says not enrolling
VNS device for long-term depression that hasn’t improved
This trial studies whether a vagus nerve stimulation (VNS) device can reduce symptoms of treatment-resistant depression. Participants either receive the VNS treatment or a no-stimulation control, to compare safety and effectiveness.
Birmingham, AlabamaAges 18 years+ - NCT07750080Recruiting
Comparing two therapies for tennis elbow in menopausal women
This study tests whether a combination of electrical therapies or shock wave therapy works better for reducing pain and improving function in menopausal women with tennis elbow that has lasted at least 3 months.
CairoAges 45–55 - NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75 - NCT05988385Recruiting
Treating sleep apnea to protect memory in older adults
This study tests whether treating sleep apnea can help protect memory and brain health in older adults. It involves using a CPAP machine or other treatments for sleep apnea and may include memory tests and brain scans over 2 years.
Tucson, ArizonaAges 55–85 - NCT07750626Recruiting
Vibration and ShotBlocker for injection pain in children
This study tests two methods to reduce pain and fear during a shot in the emergency department. It compares using a vibration device or a ShotBlocker device against standard care.
BurdurAges 5–10 - NCT07326891Recruiting
Mediterranean diet with cycling and rowing for blood sugar in prediabetic women
This trial tests whether following a Mediterranean diet and doing cycling and rowing exercise can help lower blood sugar in women with prediabetes. It may help you find a safe way to prevent or delay diabetes.
Beykoz, IstanbulAges 22–55 - NCT07745881Recruiting
Pain relief after lung cancer surgery
This trial tests a nerve block that may reduce pain after surgery for lung cancer. It's a technique that numbs a specific area in the back to help you feel more comfortable during recovery.
Nanjing, JiangsuAges 18–80 - NCT07748949Recruiting
Low-calorie diet and lifestyle help for type 2 diabetes
This study tests whether a low-calorie diet combined with a personalized lifestyle program can help people with type 2 diabetes reach remission, meaning their blood sugar stays normal without needing diabetes medication. It uses a smartphone app to support the program.
BangkokAges 18–70 - NCT07416604RecruitingPhase 3
Study of NXT007 vs emicizumab for hemophilia A
This trial tests if a new medicine, NXT007, is better than emicizumab at preventing bleeding episodes in people with hemophilia A. It may be an option for those with or without inhibitors who are willing to switch to a preventive treatment.
Orange, CaliforniaAges 12 years+ - NCT04743791RecruitingPhase 4
Dupilumab study for clearing mucus in moderate to severe asthma
This study tests whether dupilumab improves how well mucus is cleared from the airways in adults with moderate to severe asthma. It may help find better ways to reduce mucus-related breathing problems in people with a specific asthma type.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07368998RecruitingPhase 2
Study of inavolisib plus fulvestrant for advanced breast cancer
This trial tests whether a new targeted pill (inavolisib) plus hormone therapy (fulvestrant) can slow or stop breast cancer growth in people whose cancer has a specific genetic change called a PIK3CA mutation. It is for patients whose disease worsened after previous hormone-and-CDK-inhibitor treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07216716Recruiting
Health app recommendation tool for Alzheimer's caregivers
This study tests a tool that helps find health apps for people caring for a loved one with Alzheimer's or a related dementia. It aims to see if the tool makes it easier to choose useful apps for your caregiving journey.
Pittsburgh, PennsylvaniaAges 18–65 - NCT06627270RecruitingPhase 2
Antibiotics before surgery for oral cancer
This trial tests if taking antibiotics and using a mouth rinse before surgery can help treat oral cancer by targeting bacteria inside the tumor. It is for people with a new diagnosis of oral cancer who are scheduled for surgery.
Cleveland, OhioAges 18 years+ - NCT07002294Recruiting
Specialist care after cardiac arrest recovery trial
This trial tests whether care from a specialist team helps people recover better after a cardiac arrest outside the hospital. If you were revived and brought to the emergency department with a pulse, you might be eligible.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05374824Recruiting
Palliative surgery versus more seizure medicines for Lennox-Gastaut
This trial compares two treatment approaches for children with Lennox-Gastaut syndrome: palliative (comfort-focused) surgery versus adding more anti-seizure medicines. It aims to see which option works better for seizure control and day-to-day well-being.
Chicago, IllinoisAges Up to 26 years - NCT07573527Recruiting
Online therapy for upper back muscle pain from trigger points
This study tests whether remote physical therapy (done online) can help relieve neck and upper back pain caused by tight knots in your rhomboid muscles. You would receive guided exercises and treatment through video calls instead of visiting a clinic in person.
Karachi, SindhAges 18–35
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,875 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.