Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06863376RecruitingPhase 2
Carbocisteine for fatty liver disease: safety and benefit study
This study tests a medicine called carbocisteine to see if it can help treat nonalcoholic fatty liver disease (NAFLD). If you have a fatty liver and no other liver or kidney conditions, this trial may explore whether this drug is safe and effective for you.
TantaAges 18–65 - NCT06867991RecruitingPhase 3
Combination therapy for autoimmune encephalitis
This study tests if combining two medications (a B-cell depleting drug and daratumumab) can help people with autoimmune encephalitis who haven't improved with standard treatments.
Zhengzhou, HenanAges 12 years+ - NCT06861010RecruitingPhase 3
Ondansetron to prevent pancreatitis after ERCP
This trial tests whether ondansetron, a medicine that helps control nausea and vomiting, can reduce the risk of pancreatitis (inflammation of the pancreas) after an ERCP procedure. If you are scheduled for an ERCP and do not have certain health issues, you may be able to join.
TantaAges 18–65 - NCT06391736RecruitingPhase 1/Phase 2
Gene therapy for late-onset Pompe disease
This trial tests a new gene therapy for late-onset Pompe disease. The therapy aims to help your body produce the enzyme needed to break down glycogen, which may improve muscle and breathing function.
BeijingAges 6 years+ - NCT06753110Recruiting
Long-term safety of OPRA implant for arm amputees
This study checks the long-term safety and how well the OPRA implant (a bone-anchored prosthetic) works for people who have an arm amputation. It is for those who already have the implant and had their second surgery at least six months ago.
Melbourne, VictoriaAges Any age - NCT05824169RecruitingPhase 1/Phase 2
Gene therapy for babies with severe spinal muscular atrophy
This early-stage study tests whether a one-time gene therapy can safely improve outcomes for babies with the most severe type of spinal muscular atrophy (SMA type 1). It focuses on safety and early signs of benefit, and participation requires specific genetic and health criteria.
BeijingAges birth–6 months - NCT06421831RecruitingPhase 1/Phase 2
Gene therapy trial for spinal muscular atrophy type 3
This trial is testing a one-time gene therapy drug for people with SMA type 3. The goal is to see if it can safely improve muscle function and strength.
Beijing, Beijing MunicipalityAges 2 years+ - NCT06853184RecruitingPhase 2
Artesunate for CMV in transplant patients
This trial tests a study drug called artesunate as a possible new treatment for CMV (a common virus) in people who have had a kidney, lung, heart, or liver transplant. It is for patients whose CMV infection requires treatment with standard antivirals like ganciclovir or valganciclovir.
Boston, MassachusettsAges 18 years+ - NCT06848946RecruitingPhase 4
Eye implant with cataract surgery vs. cataract surgery alone
This trial tests if a tiny implant called iDose® TR, placed during cataract surgery, can better control eye pressure in people with glaucoma or high eye pressure compared to cataract surgery alone.
Kenosha, WisconsinAges 45 years+ - NCT06849258Recruiting
FloStent for enlarged prostate symptoms trial
This trial tests a new device called the FloStent, a small tube placed in the urine channel to help men with an enlarged prostate pee more easily. It's for men who have moderate to severe symptoms and haven't had prostate surgery before.
Bakersfield, CaliforniaAges 45 years+ - NCT06850727RecruitingPhase 2
Study of OD-07656 then vedolizumab for ulcerative colitis
This trial tests a new drug, OD-07656, followed by vedolizumab, in people with moderate to severe ulcerative colitis. It aims to see if this approach is safe and helps control symptoms when other treatments have not worked well.
BirtinyaAges 18–75 - NCT06854796Enrolling by invitation
Collagen gel for nose-to-mouth lines
This trial is testing a new collagen gel to reduce moderate to deep nose-to-mouth lines. It compares the gel to a control (no active treatment) to see if it works better and is safe.
BeijingAges 18–65 - NCT06850805RecruitingPhase 3
Nasal spray for teens with chronic sinusitis without polyps
This study tests a new nasal spray (OPN-375) for teens aged 12–17 with chronic sinusitis but without nasal polyps. It aims to see if the spray improves symptoms like congestion and runny nose.
Huntsville, AlabamaAges 12–17 - NCT06848894Enrolling by invitation
Study of a drug for stroke patients after blood clot treatment
This trial tests if adding a drug called human urinary kallidinogenase (HUK) can improve recovery for people who have had a stroke and already received clot-busting medicine or a procedure to remove the clot. The goal is to see if it helps reduce disability after a stroke.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06853223RecruitingPhase 2
Immune drug to prevent lung transplant failure
This trial tests an immune-suppressing medicine to stop a serious complication called primary graft dysfunction that can happen soon after a lung transplant. It may help people who are already on the transplant waiting list and plan to receive a standard anti-rejection drug regimen.
San Francisco, CaliforniaAges 18 years+ - NCT06847399RecruitingPhase 2
Tirzepatide for Binge Eating Disorder
This trial tests if tirzepatide (a weekly injection) can help reduce binge eating compared to a placebo or another medication (lisdexamfetamine dimesylate). It may be a good fit for people with moderate or severe binge eating disorder who also have a high body weight.
Baltimore, MarylandAges 18 years+ - NCT06843044RecruitingPhase 4
Testing Ranquilon for anxiety from stress or exhaustion
This study tests a new medication called Ranquilon to see how well it treats anxiety in people with neurasthenia or adjustment disorders. Participants will take the study drug for about 4 weeks, and doctors will check their anxiety and fatigue levels.
Engel'sAges 18–70 - NCT06846281RecruitingPhase 3
Remibrutinib for relapsing multiple sclerosis after switching from Ocrevus
This study tests a new oral medication called remibrutinib for people with relapsing multiple sclerosis who are currently on Ocrevus. Participants will switch from Ocrevus to remibrutinib to see if it is safe and effective.
Scottsdale, ArizonaAges 40–70 - NCT06843018RecruitingPhase 2
Spray vs lozenge for sore throat from infection
This trial tests a new spray with anesthetic for sore throat caused by infections like pharyngitis. It compares the spray to a lozenge (Septolete Total) to see which works better and is safer.
Engel'sAges 18–75 - NCT06845553RecruitingPhase 2
Vutiglabridin for knee osteoarthritis: a phase 2 study
This trial tests an experimental pill called Vutiglabridin for people with knee osteoarthritis. It aims to see if the drug is safe and effective at reducing knee pain and improving function.
Seongnam-si, Gyeonggi-doAges 40–75 - NCT06403501RecruitingPhase 3
Clascoterone cream for facial acne
This trial tests a new cream called clascoterone for moderate to severe facial acne. It may help reduce pimples and blackheads with fewer side effects than some other treatments.
ShanghaiAges 12 years+ - NCT06577558RecruitingPhase 2
SR1375 for severe pneumonia not improving on antibiotics
This trial tests a new drug called SR1375 for adults with severe community-acquired pneumonia (a lung infection) who are not improving with standard antibiotics. It may help reduce inflammation and speed up recovery.
Fuyang, AnhuiAges 18–85 - NCT06845904Recruiting
Spinal cord stimulation for bladder control after injury
This trial tests whether using mild electrical pulses on the spinal cord can help people with spinal cord injuries regain better control of their bladder. It might be an option if you've tried other treatments without success.
Lausanne, Canton of VaudAges 18 years+ - NCT06839547Recruiting
Testing a new drug with radiation for advanced breast cancer brain tumors
This study looks at how well a new anti-tumor drug works when given along with radiation therapy for people whose advanced breast cancer has spread to the brain. It may help the radiation work better and control the cancer longer.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.