Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06945614RecruitingPhase 1
Xenon gas for brain inflammation safety study
This study tests an inhaled gas called xenon to see if it can safely reduce brain inflammation. The study is for healthy volunteers aged 55-75 to check safety and early signs of benefit.
Boston, MassachusettsAges 55–75 - NCT06947707Recruiting
Blood thinners for brain blood clot in Chinese patients
This trial tests two blood thinner medicines, edoxaban and rivaroxaban, in Chinese patients with a blood clot in a brain vein (cerebral venous thrombosis). It aims to see if these medicines are safe and work well.
Beijing, Beijing MunicipalityAges 18–80 - NCT06947941RecruitingPhase 3
Testing karxt for psychosis in alzheimer's disease
This study tests whether a new medicine called KarXT can help with psychosis (hallucinations or delusions) in people with Alzheimer's disease. It aims to reduce troubling symptoms while being safe for older adults.
Gilbert, ArizonaAges 55–90 - NCT06947993RecruitingPhase 2
Study of a new treatment for moderate to severe eczema
This study tests an experimental treatment for people with moderate to severe eczema that has lasted at least a year. It aims to see if the new medicine can help control symptoms better than current options.
Birmingham, AlabamaAges 18–100 - NCT06948357RecruitingPhase 2
Eye drops for presbyopia in Chinese adults
This trial tests two eye drops, BRIMOCHOL PF and CARBACHOL PF, to see if they improve near vision in people with presbyopia (age-related difficulty seeing up close). The study is for Chinese adults aged 45-75 who have trouble reading even with glasses or contacts.
Wenzhou, ZhejiangAges 45–75 - NCT06948487Recruiting
Study of Fexuclu tablets for stomach inflammation (gastritis)
This study watches patients with acute or chronic gastritis who are already being prescribed the stomach medicine Fexuclu (fexuprazan). It collects information to see how well the medicine works and if it causes any side effects in everyday use.
SeoulAges 19–75 - NCT06949982RecruitingPhase 2
Comparing two treatments for advanced colorectal cancer with RAS mutations
This trial tests if a combination of hydroxychloroquine, methotrexate, capecitabine, and bevacizumab works better than regorafenib for people with metastatic colorectal cancer that has a RAS gene mutation and has stopped responding to at least two prior treatments.
Saint Petersburg, Sankt-PeterburgAges 18 years+ - NCT06951854RecruitingPhase 2
Testing a new drug for children with autism
This trial tests a new medicine (NV01-A02) in children aged 6 to 15 who have autism. The goal is to see if the drug is safe and helpful for managing autism symptoms.
Seoul, SeoulAges 6–15 - NCT06952413RecruitingPhase 2
Rituximab for chronic fatigue syndrome (ME/CFS) trial
This trial tests if rituximab, a drug that affects the immune system, can help people with ME/CFS. You'll receive the drug in the hospital and be monitored for safety and improvement.
Kodaira, TokyoAges 18–65 - NCT06952478RecruitingPhase 3
Comparing a new injectable multiple myeloma drug to Darzalex Faspro
This trial compares a new injectable medicine (CT-P44) to an approved one (Darzalex Faspro), both given with lenalidomide and dexamethasone, for people whose multiple myeloma has come back or stopped responding to treatment. It aims to see if the new option works just as well.
Taipei, Beitou DistrictAges 18 years+ - NCT06952517RecruitingPhase 2
Clascoterone cream for rosacea bumps and pimples
This study tests a cream called clascoterone (already approved for acne) to see if it can help treat facial rosacea that causes bumps and pimples. Participants will use the cream daily and attend regular check-ups to see if their skin improves.
Brooklyn, New YorkAges 18 years+ - NCT06952842RecruitingPhase 1/Phase 2
Gene therapy trial for retinitis pigmentosa with RHO mutation
This trial tests a new gene therapy called ZVS203e for people with retinitis pigmentosa caused by a specific RHO gene mutation. It aims to see if the treatment is safe and can help improve vision.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06953726RecruitingPhase 4
Comparing apixaban and rivaroxaban for atrial fibrillation
This study compares two common blood thinners, apixaban and rivaroxaban, in veterans with atrial fibrillation or flutter to see which one is safer and works better. If you are already taking one of these medicines, you may be able to join.
Miami, FloridaAges 65 years+ - NCT06957093Recruiting
AI‐assisted diabetes care vs standard management
This study tests whether an AI‐powered digital health platform can help people with type 2 diabetes better manage their blood sugar. If you use a smartphone and have had diabetes for at least a year, this may be a convenient way to receive extra support.
Changchun, JilinAges 18–75 - NCT06957691RecruitingPhase 2
Fezolinetant for hot flashes in men on hormone therapy
This study tests whether a medication called fezolinetant can reduce hot flashes in men with prostate cancer caused by hormone therapy (ADT). If you have frequent, bothersome hot flashes, this treatment may help.
Boston, MassachusettsAges 40 years+ - NCT06958536RecruitingPhase 2
Testing a new drug for moderate to severe Crohn's disease
This study tests an experimental drug called SAR442970 for people with moderate to severe Crohn's disease who haven't had success with standard treatments or biologics. The goal is to see if it can reduce inflammation and improve symptoms.
Tucson, ArizonaAges 18–75 - NCT06959030Recruiting
Study of Henagliflozin for Type 2 Diabetes
This study tests how safe and effective the diabetes medication henagliflozin is for Chinese patients with type 2 diabetes. It is an observational study, meaning you will continue your regular care while researchers watch your progress.
Beihai, GuangxiAges 18–80 - NCT06960018Recruiting
Ennovate minimally invasive spinal screw placement study
This study tests a new, less invasive method for placing screws in the cervical spine (upper back and neck). It is designed for patients who need spinal stabilization after injury or degeneration.
AachenAges 18 years+ - NCT06962098RecruitingPhase 2
Study of isuzinaxib for diabetic kidney disease
This trial tests an investigational drug called isuzinaxib (APX-115) for people with type 2 diabetes and diabetic kidney disease (DKD). The goal is to see if it can help protect kidney function. Participants must have stable kidney lab values and be on certain blood pressure or diabetes medications.
Ansan-siAges 19 years+ - NCT06963710RecruitingPhase 2
New Hepatitis B Treatment vs Standard Drug
This trial tests a new oral medication (ALG-000184) compared to an existing drug (tenofovir) for people with chronic hepatitis B who have not been treated recently. It aims to see if the new drug is better at lowering the virus and improving liver health.
Chandler, ArizonaAges 18–65 - NCT06964620RecruitingEarly Phase 1
Sanggua Tablets for prediabetes and mild type 2 diabetes
This trial tests whether Sanggua Tablets, an herbal medicine, can help people with prediabetes or mild type 2 diabetes improve their blood sugar control without needing other medications.
Wuhan, HubeiAges 18–70 - NCT06966284Recruiting
Study Comparing Two Antibiotics for Resistant Infections
This study looks at two strong antibiotics, polymyxin B and colistin, given through a vein to treat serious infections like pneumonia or blood infections caused by bacteria that are resistant to many other antibiotics. The goal is to see how well they work and how safe they are.
TaipeiAges 18 years+ - NCT06967012RecruitingPhase 4
Zonisamide as add-on treatment for children with epilepsy
This trial tests adding zonisamide to the current epilepsy medication for children aged 1 to 14 who still have focal seizures. The goal is to see if the combination works better and is safe.
Nantong, JiangsuAges 1–14 - NCT06967857RecruitingPhase 2
Dexamfetamine for adults with ADHD and depression
This trial tests a study medication (dexamfetamine) for adults who have both ADHD and moderate to severe depression. It aims to see if the medication is safe and helps improve both conditions.
FrankfurtAges 18–65
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.