Clinical trials
Emergency Department clinical trials
Below are recruiting emergency department clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05549752RecruitingPhase 3
Flecainide vs amiodarone to treat fast heart rhythm in ER
This trial compares two medicines—flecainide and amiodarone—to help restore normal rhythm during an emergency visit for paroxysmal atrial fibrillation (a-fib). It’s aimed at people who also have coronary artery disease but no ongoing (residual) heart ischemia, and who have enough heart pumping strength.
AthensAges 18–85 - NCT06927193Recruiting
Pain relief for kids in the emergency room
This trial looks back at how well nerve blocks work for children who received them in the emergency department. If your child had a nerve block during an ER visit from 2023 to 2025, this study may include their experience.
HaderaAges Up to 18 years - NCT06903442Recruiting
Helping ER chest pain patients understand heart risk
This study is testing a new way to talk with people about their heart health after they come to the Emergency Room with chest pain. It aims to help you understand your risk and what you can do to prevent future problems.
EdinburghAges 18 years+ - NCT06889792Recruiting
Preventing disease with healthy lifestyle screening in the ER
This trial tests if screening and education in the emergency department can help people adopt healthier habits to prevent long-term diseases. You may join if you have at least one unhealthy behavior like smoking, drinking too much alcohol, poor diet, or not exercising.
Hong KongAges 18 years+ - NCT05931601RecruitingPhase 3
Early blood-pressure support in the emergency department
This Phase 3 study tests whether starting a blood-pressure medicine earlier in the emergency room can improve outcomes for people with low blood pressure or shock. It focuses on patients who have already received enough IV fluids and meet specific blood pressure and lab findings.
CopenhagenAges 18 years+ - NCT06872190Recruiting
CDS tool for opioid use disorder in the ED
This trial tests a clinical decision support tool for emergency department providers at UCSF. It helps doctors give better care that considers social needs alongside opioid use treatment. The study will ask providers and patients about how well this tool works.
San Francisco, CaliforniaAges 18 years+ - NCT06845826Recruiting
Quick Troponin Test in the ER for Chest Pain
This trial is checking a quick bedside blood test (troponin) for people who come to the emergency room with chest pain. It aims to see if the test can help doctors decide faster if you are having a heart attack.
Leuven, Vlaams-BrabantAges 18–75 - NCT06834646Recruiting
Comparing emergency care outcomes for cancer patients
This study looks at how cancer patients fare in different emergency departments over 30 days. It aims to find which settings lead to better outcomes for people with active cancer or who finished treatment less than a year ago.
ParisAges 18 years+ - NCT06827288Recruiting
Helping emergency patients with opioid use disorder
This study tests different ways to help people who come to the emergency department with opioid use disorder. It aims to find which support strategies work best to connect them with ongoing care and reduce harm.
Colton, CaliforniaAges 18 years+ - NCT06785272RecruitingPhase 3
Magnesium for children with asthma in the ER
This trial tests if giving magnesium sulfate through an IV helps children with moderate to severe asthma attacks in the emergency department. If your child is between 2 and 17 years old and still has trouble breathing after three puffs of standard asthma medicine, this study may be an option.
Calgary, AlbertaAges 2–17 - NCT06745453Recruiting
Nerve block for back pain in the ER
This trial tests whether a numbing injection near your spine can quickly relieve sudden back pain that has lasted less than six weeks. If it works, it could be a fast, non-opioid option during an ER visit.
Chicago, IllinoisAges 18 years+ - NCT06733974Recruiting
Support for families of dying patients in the ER
This study tests a program designed to support relatives when a loved one is dying in the emergency department. It aims to see if extra guidance and follow-up calls can help families during this difficult time.
Paris, ParisAges 18 years+ - NCT06724991Enrolling by invitation
Lower vs standard insulin dose for high potassium in ER
This study compares a lower dose versus a standard dose of insulin and dextrose (sugar water) to treat moderately high potassium levels in emergency department patients. It aims to see if a lower dose works just as well with fewer side effects.
Kuala LumpurAges 18–100 - NCT06693726RecruitingPhase 4
Early blood pressure medication in the ER
This trial tests a drug called angiotensin II for people in the emergency room who need a specific dose of norepinephrine (a medicine to raise blood pressure) and are also getting antibiotics. The goal is to see if giving angiotensin II early can help stabilize blood pressure.
Iowa City, IowaAges 18–99 - NCT06675461Enrolling by invitation
Brief talk therapy for suicidal patients with borderline personality disorder
This trial tests a short talk therapy for people with borderline personality disorder who come to the emergency department after hurting themselves or thinking about suicide. The goal is to see if this brief help can ease suicidal thoughts and keep you safer.
Toronto, OntarioAges 16 years+ - NCT06660901Recruiting
Study on cannabis use and vomiting in emergency rooms
This study looks at patients who come to the ER with belly pain or vomiting and uses cannabis, to better understand a condition called cannabinoid hyperemesis syndrome (severe nausea and vomiting caused by long-term cannabis use). If you're eligible, you'll answer a few questions to help doctors learn more.
AngersAges 18–65 - NCT06660199Recruiting
Text Support for Parents of Teens After a Suicidal Crisis
This study tests a text-message program to support parents of teens who come to the ER after suicidal thoughts or attempts. The goal is to see if the program helps parents and teens after they go home.
Ann Arbor, MichiganAges 13 years+ - NCT06645106Recruiting
Rapid syphilis testing for pregnant patients in the ER
This trial offers quick, on-the-spot syphilis testing for pregnant people who come to the emergency department or obstetrical triage and haven't had prenatal care or a syphilis test yet during this pregnancy. It aims to make testing easier and faster so you can get care if needed.
Houston, TexasAges 18–50 - NCT06618989Recruiting
Predicting serious bacterial infection in febrile infants
This trial is testing a new blood test to help doctors tell which babies under three months with fever are at risk for a serious bacterial infection. If successful, it could help avoid unnecessary antibiotics and hospital stays.
Paris, FranceAges 1 week–3 months - NCT06603662RecruitingPhase 4
Steroids for sudden osteoarthritis pain in the emergency room
This trial tests if a short course of oral steroids (glucocorticoids) can relieve sudden osteoarthritis pain in the knee, hip, or shoulder for people who come to the emergency department and are well enough to go home.
York, PennsylvaniaAges 18 years+ - NCT06605534Recruiting
Lung cancer screening study for current and past smokers
This study uses the emergency department to offer lung cancer screening to people who smoke or recently quit. It aims to catch lung cancer early, when it's easier to treat.
Brick, New JerseyAges 50–80 - NCT06592378Recruiting
Managing pain after a broken bone with a smartphone app
This trial tests whether a smartphone app can help patients manage opioid pain medication safely after being discharged from the emergency room with a broken bone. If you have a simple fracture and plan to take opioids for pain, the app may help you track your use and recovery.
Providence, Rhode IslandAges 6 years+ - NCT06071078Recruiting
Study on how a special talk affects family stress in ER
This study tests if a structured way of telling families about a decision to stop or limit life support in the emergency room can reduce stress for loved ones. It involves family members who are present in the ER when they first hear this news.
AngersAges 18 years+ - NCT06464146RecruitingPhase 3
Comparing nose and mouth pain medicines for broken bones in kids
This study compares three different fast-acting pain medicines given through the nose or by mouth to children with a suspected broken arm or leg in the emergency room. The goal is to find which medicine works best for pain relief within the first hour.
Boulogne-BillancourtAges 2–17
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Common questions
- Are there clinical trials for emergency department?
- Yes. Clin2 currently lists 172 recruiting emergency department studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a emergency department trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a emergency department trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.