Clinical trials
Emergency Department clinical trials
Below are recruiting emergency department clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06448091Recruiting
Precision Medicine in the Emergency Room
This study tests whether using genetic information in the emergency department can help choose safer medications for patients 40 and older. It focuses on people who frequently visit the ER and are starting a new long-term medication.
Gainesville, FloridaAges 40 years+ - NCT06408142Recruiting
HIV testing and connection to care in South African ERs
This study tests a program that offers HIV testing and connects people to prevention or care right in the Emergency Department. It aims to make it easier for anyone visiting the ER to get the HIV services they need.
Cape Town, Western CapeAges 12 years+ - NCT06420206Recruiting
Goals of care discussion in the ER for advanced cancer
This study is for people with advanced lung or GI cancer who come to the emergency room at MD Anderson. It’s testing a conversation to help you and your doctor discuss your goals and wishes for care.
Houston, TexasAges 18 years+ - NCT06311591Enrolling by invitation
Jaspr Health for suicide risk in the emergency department
This study tests a program called Jaspr Health, which is designed to help people who are at risk for suicide. If you are in the emergency department, Jaspr may give you tools and support to help you feel safer.
Aurora, ColoradoAges 18 years+ - NCT06306183Recruiting
Vitamin C for pain relief after an ER visit
This trial tests whether a high dose of vitamin C can help reduce pain for people who come to the emergency department with new muscle or bone pain. If you qualify, you will receive vitamin C or a placebo and track your pain over time.
Ottawa, OntarioAges 18 years+ - NCT06223867Recruiting
Jaspr Health app for suicide prevention in the emergency department
This trial tests whether using the Jaspr Health app in the emergency department helps people who are having thoughts of suicide or have recently attempted suicide. The app is designed to provide support and coping strategies.
Worcester, MassachusettsAges 18 years+ - NCT06085937RecruitingPhase 1
Ketamine for suicidal patients in the ER
This trial tests if a single dose of ketamine can quickly reduce suicidal thoughts in people who come to the emergency department. If you are having active suicidal thoughts and need inpatient care, you may be able to join.
Kansas City, KansasAges 18–65 - NCT06065761Enrolling by invitation
Better risk assessment for heart failure in the ER
This trial looks at ways to better understand how serious heart failure is for people who come to the emergency room. It could help doctors decide on the best treatment more quickly.
Antioch, CaliforniaAges 18 years+ - NCT06060639Recruiting
Heart ultrasound after blood transfusion in emergency patients
This study uses ultrasound (echocardiogram) to see how a blood transfusion affects heart function in people with low red blood cells (anemia) in the emergency room.
Nîmes, GardAges 60 years+ - NCT05888974Recruiting
Test of heart ultrasound to guide fluids in shock
This study checks whether a specific heart ultrasound measurement can help doctors decide if you will benefit from extra fluid during early emergency treatment for shock. It may help avoid unnecessary fluids and support faster, safer decision-making.
NîmesAges 18 years+ - NCT05823220Enrolling by invitation
Homelessness support added to hospital discharge planning
This trial tests whether adding homelessness “diversion” services to emergency department discharge plans can help people avoid becoming homeless. It may be helpful if you’ve just left the hospital and you’re at high risk of housing instability.
Houston, TexasAges 18 years+ - NCT05762302Recruiting
Testing a blood test to guide antibiotics for lung infections
This trial studies whether using the MeMed BV® blood test in the emergency room or urgent care can help doctors decide when antibiotics are (or are not) needed for suspected lung infections. It may help reduce unnecessary antibiotics while still treating infections when needed.
Jacksonville, FloridaAges 18–99 - NCT05691218Recruiting
Early high-flow oxygen plus nebulized asthma medicine
This study tests whether giving fast, high-flow oxygen early—together with inhaled terbutaline via a vibrating mist—helps adults with moderate to severe asthma flare-ups in the emergency department. It aims to see if this approach improves breathing after initial treatment.
Poitiers, FranceAges 18 years+ - NCT05589181RecruitingPhase 3
High-dose buprenorphine start in the emergency department for fentanyl use
This Phase 3 study tests whether starting a high dose of buprenorphine in the emergency department helps people with opioid use disorder come through withdrawal more safely and effectively. It focuses on people whose urine test shows fentanyl and who are already in withdrawal when they arrive.
Newark, New JerseyAges 18 years+ - NCT05555576Recruiting
Vitamin C to reduce opioid use after an ER visit
This trial tests whether taking vitamin C after an emergency room visit for a new, short-term muscle or joint pain can lower how many opioid pain pills you use. It may help by reducing opioid consumption while you recover.
Montreal, QuebecAges 18 years+ - NCT05555771Recruiting
Kids with fainting episodes after arriving at the emergency room
This study looks at children and teens (ages 6–18) who recently fainted but are now back to normal, using a survey. It aims to better understand fainting episodes that happen before the emergency visit and how to evaluate them safely.
Vancouver, British ColumbiaAges 6–18 - NCT05540106Recruiting
Art therapy to reduce pain and anxiety in the ER waiting room
This trial studies whether guided art therapy can lower the pain and anxiety you feel while waiting to be seen in the emergency department. It may help you feel more calm and comfortable during the waiting time.
Stony Brook, New YorkAges 18 years+ - NCT05400707Recruiting
Tracking symptoms and other clues in emergency room visits
This study follows people who come to the emergency department to see what symptoms and other factors can help predict what happens next. It may help improve how emergencies are quickly triaged and managed.
BaselAges 18 years+ - NCT05307432Enrolling by invitation
Telehealth safety planning after an ER visit for suicide risk
This study tests a phone/video-based “safety plan” service for adults after an ER visit related to suicide risk. It may help you (or the ER team) feel more prepared to stay safe and know what to do next after you leave the hospital.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05066347Recruiting
Remote heart monitoring after fainting discharge from the ER
This trial studies whether remote heart monitoring after an ER visit for fainting (syncope) can help identify dangerous heart problems. You may be enrolled only if your fainting episode seems medium- to high-risk and you’re being sent home from the ER.
Ottawa, OntarioAges 18 years+ - NCT05050617Recruiting
Ultrasound in the ER to predict risks in pulmonary embolism
This trial checks whether a bedside ultrasound done in the emergency room can help predict which people with an acute pulmonary embolism are more likely to have bad outcomes. If you qualify, your care team will compare ultrasound findings with your later results to see if it can guide treatment decisions sooner.
York, PennsylvaniaAges 18 years+ - NCT04893525RecruitingPhase 2/Phase 3
Buprenorphine-naloxone microdosing versus standard dosing after ED discharge
This study compares a smaller “microdose” starting method versus the usual starting dose of buprenorphine/naloxone for people with opioid use disorder when they are discharged from the emergency department. It may help find a safer, easier way to start treatment right after an ED visit and avoid problems caused by starting too early.
Calgary, AlbertaAges 18 years+ - NCT04163081Recruiting
Help to quit smoking started from the emergency department
This study tests a program to help people who smoke quit, beginning when they are seen in the emergency department. It aims to see if starting nicotine-cessation support right away improves quitting over the next year.
Ottawa, OntarioAges 18 years+ - NCT00870064Recruiting
Study of treating small open bone breaks in children
This study looks at how to treat certain small open fractures (where a bone has broken through the skin) in children using non-surgical realignment when possible. It may help doctors confirm the best early treatment approach for less severe injuries.
Chicago, IllinoisAges 3–14
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Common questions
- Are there clinical trials for emergency department?
- Yes. Clin2 currently lists 172 recruiting emergency department studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a emergency department trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a emergency department trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.