Flecainide vs amiodarone to treat fast heart rhythm in ER
Treatments studied
Part of Heart & circulation clinical trials.
This trial compares two medicines—flecainide and amiodarone—to help restore normal rhythm during an emergency visit for paroxysmal atrial fibrillation (a-fib). It’s aimed at people who also have coronary artery disease but no ongoing (residual) heart ischemia, and who have enough heart pumping strength.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 85 years old
- Have paroxysmal atrial fibrillation on an ECG (a-fib comes and goes)
- Come to the emergency department within 48 hours of a-fib starting, or within 48 hours to 7 days if you’ve been on blood thinners for at least 30 days
- Have coronary artery disease but no residual ischemia (not ongoing blockage causing reduced blood flow)
- Have heart pumping strength (ejection fraction) above 35% and be able to sign consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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