Clinical trials
Epigenetics clinical trials
Below are recruiting epigenetics clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03402139Recruiting
Study early-life obesity risk after growth restriction
This study looks at how obesity risk may be influenced in children whose growth was lower than expected before birth. It enrolls mothers and babies together to learn whether early childhood obesity programming can help families.
The Bronx, New YorkAges 1 hour–2 years - NCT03742011Recruiting
Study of babies born to mothers with PCOS in Guangzhou
This study looks at children born to mothers who have polycystic ovary syndrome (PCOS). It aims to learn about their health by following families in Guangzhou over time.
Guangzhou, GuangdongAges Up to 18 years - NCT03855657Recruiting
Biobank study of gut microbes, genes, and blood chemistry
This study collects samples to learn how gut microbes, genetics, and body chemistry may relate to Crohn’s disease or ulcerative colitis. Your information and samples may help researchers understand disease patterns, but it does not test a new drug.
Hong KongAges 18 years+ - NCT04187703RecruitingEarly Phase 1
Testing azacitidine and decitabine for bone marrow cancers
This early-phase study tests whether combining two “epigenetic” medicines—azacitidine and decitabine—can improve outcomes for certain bone marrow cancers. It may help if you have a type of myelodysplastic syndrome (MDS) or MDS/MPN overlap that is expected to be sensitive to these medicines.
Cleveland, OhioAges 18 years+ - NCT04714957Recruiting
Personalized study for cancer spread in the belly lining
This trial studies people whose cancer has spread to the lining of the abdomen (the “belly lining”), including cancers from the digestive tract or ovaries. You may be asked to join because the study aims to learn how to better match care to different patterns of this belly lining cancer spread.
LyonAges 18 years+ - NCT04814407Recruiting
Test blood and other markers to detect early lung cancer
This study looks for new “epigenetic” signals in blood (signals about how genes are turned on/off) to help detect lung cancer early. You might be able to join if you are being evaluated for possible lung cancer or have small, unclear spots on a lung CT scan.
TaipeiAges 20 years+ - NCT05317403RecruitingPhase 1
Venetoclax plus chemo to change cancer cell behavior
This Phase 1 trial tests whether venetoclax, combined with chemotherapy and a “cancer cell behavior” medicine strategy, can improve treatment for people with AML that has come back or not gone into remission. It’s mainly looking at safety and early signs of benefit.
Milwaukee, WisconsinAges 1–25 - NCT05636514RecruitingPhase 1
Testing epigenetic and sensitizer treatment for AML and MDS
This early-phase trial tests whether a combination of targeted medicines can improve outcomes in people with higher-risk MDS or certain types of AML or CMML. It’s designed to find the safest dose and learn if the treatment can help the cancer respond.
Sydney, New South WalesAges 18 years+ - NCT05765864Recruiting
Study of self-harm in at-risk teens
This study looks at self-harm and thoughts/behaviors related to safety in teenagers who are considered at higher risk. It may help researchers better understand what supports are needed for teens who self-harm without wanting to die.
LjubljanaAges 13–18 - NCT05767216Recruiting
Study of genetic and epigenetic differences in twin pairs with Down syndrome
This study looks at how genetics and gene-regulation (how genes turn on and off) differ between close family members who have different Down syndrome status. Researchers hope the findings will help explain why Down syndrome outcomes can vary even in very closely related people.
ParisAges 4–11 - NCT05958719RecruitingPhase 2
Chidamide plus chemotherapy for new nodal TFH cell lymphoma
This trial studies whether adding chidamide to a combination chemotherapy plan (azacitidine, liposomal mitoxantrone, and prednisone) works better for people newly diagnosed with nodal T-follicular helper (TFH) cell lymphoma. It’s testing a treatment strategy after diagnosis to improve disease control and outcomes.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06337227Recruiting
Studying sirtuins as biomarkers for artery or heart valve disease
This study tests whether proteins called sirtuins can be used as biomarkers (biological clues) to better understand patients with hardened arteries (atherosclerosis) or calcified heart valve disease (calcific aortic stenosis), especially if you also have diabetes. It may help doctors develop better ways to diagnose or monitor these conditions.
NaplesAges 18 years+ - NCT06373822Recruiting
Understanding adenomyosis through genetics
This trial studies genetic factors (epigenetics and miRNAs) to understand why adenomyosis develops. By comparing tissue samples, researchers hope to find new ways to diagnose or treat this condition.
Brussels, Woluwe-Saint-LambertAges 18 years+ - NCT06446947Recruiting
Blood markers for poor outcomes after sepsis in cancer surgery
This study looks at blood markers (epigenetics) to better understand why some people have a harder time recovering from a severe infection after major cancer surgery. The goal is to find early signs of poor outcomes in men aged 45–75 with post-surgery sepsis.
Marseille, Bouches du RhôneAges 45–75 - NCT06471387Recruiting
Study of genes linked to nicotine addiction
This study looks at your genes to understand why some people get addicted to nicotine. Your participation could help develop new treatments for quitting smoking.
NicosiaAges 18–60 - NCT06507007Recruiting
Inner ear function in Turner syndrome
This study looks at why some people with Turner syndrome have inner ear problems. It uses MRI and CBCT scans to understand the genetic and epigenetic causes.
HerningAges 18–60 - NCT06516237Recruiting
New imaging for fibrosis in ulcerative colitis
This study looks at new ways to detect scarring (fibrosis) in the bowel using advanced imaging and tests. It may help doctors better understand and monitor ulcerative colitis. If you are already having a colonoscopy, you may be able to join.
Milan, LombardyAges 18 years+ - NCT06542393RecruitingPhase 2
Blood management for anemic patients having bypass surgery
This trial tests a blood management strategy to help people with anemia who are having coronary artery bypass surgery (CABG). If you qualify, you may receive a treatment to improve your blood counts before surgery, which could reduce the need for transfusions.
São Paulo, São PauloAges 18–80 - NCT06706687Recruiting
Brain imaging and epigenetics in frontotemporal dementia and bipolar disorder
This study uses brain scans and genetic tests to understand the differences between behavioral variant frontotemporal dementia (bvFTD) and bipolar disorder. It may help improve diagnosis and find better treatments for both conditions.
Milan, MIAges 18 years+ - NCT06706973Recruiting
Epigenetic study for new head and neck cancer treatments
This trial studies the role of epigenetic marks in head and neck cancer to improve diagnosis and treatment. If you have been newly diagnosed with head and neck squamous cell carcinoma and have not yet received treatment, you may be eligible to participate.
Milan, MIAges 18 years+ - NCT06740266Recruiting
Parenting support for mothers and their babies
This study tests if a specially designed parenting program can help mothers and their babies bond better and possibly affect the baby's cells in a positive way. If you are a mother with a baby between 3 and 12 months old, receiving Medicaid, and getting care at WakeMed, you may be able to join.
Raleigh, North CarolinaAges 18 years+ - NCT06759714Recruiting
Epigenetic markers in newly diagnosed breast cancer
This study looks at specific molecules in the body that can change how your genes work (epigenetic mediators) in women who have just been diagnosed with breast cancer. The goal is to understand these markers better, which could help improve treatment in the future.
CairoAges 18 years+ - NCT06771583Recruiting
Finding biomarkers for PMDD in blood samples
This study looks for chemical markers in the blood that might help diagnose PMDD. It involves blood draws and questionnaires over one or two menstrual cycles to see how your body responds to natural hormone changes.
Baltimore, MarylandAges 18–50 - NCT06944145RecruitingPhase 2
New treatment study for enlarged prostate (BPH)
This trial tests new treatment strategies for benign prostatic hyperplasia (BPH, an enlarged prostate) using a special MRI scan and a medication called finasteride. It aims to find better ways to manage symptoms and identify markers that predict response.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for epigenetics?
- Yes. Clin2 currently lists 65 recruiting epigenetics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epigenetics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epigenetics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.