Clinical trials
Focused Ultrasound clinical trials
Below are recruiting focused ultrasound clinical trials, each written for real people, not researchers. We’re tracking 104 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06039709RecruitingPhase 1
Sound wave therapy for recurrent glioblastoma
This trial tests a new treatment called sonodynamic therapy that uses sound waves and a special drug to target brain tumors that have come back. It aims to see if this approach is safe and can shrink tumors in people who are eligible for surgery.
Charlottesville, VirginiaAges 18–80 - NCT06053255Recruiting
Testing a new device for low back pain from sacroiliitis
This trial tests a device called the Neurolyser XR to treat chronic low back pain caused by inflammation of the sacroiliac joint. It may help if you've had pain for over a year and other treatments haven't worked.
Charlottesville, VirginiaAges 18 years+ - NCT06331052Recruiting
Focused Ultrasound for Essential Tremor
This trial tests a focused ultrasound treatment for essential tremor that uses MRI to guide sound waves to stop the shaking. It might help if other treatments haven't worked well enough.
Chapel Hill, North CarolinaAges 22 years+ - NCT06388707RecruitingPhase 1/Phase 2
Ultrasound brain stimulation for drug-resistant epilepsy
This trial tests a low-intensity focused ultrasound device that aims to calm overactive brain areas causing seizures. It's for people whose seizures are not controlled by medication.
Palo Alto, CaliforniaAges 18 years+ - NCT07691918Enrolling by invitation
Brain stimulation for mild memory loss
This trial tests if a non-invasive brain stimulation technique can help people with mild memory problems. It uses a special cap to gently stimulate the brain and aims to improve thinking and memory.
Roanoke, VirginiaAges 55–80 - NCT06492720Recruiting
Testing focused ultrasound for drug-resistant epilepsy
This study tests a new device called NaviFUS that uses focused sound waves to gently stimulate a small area of the brain. It is for people whose seizures start in one part of the brain and are not fully controlled by seizure medicines.
TaipeiAges 18–65 - NCT06524570RecruitingPhase 1
Focused ultrasound plus immune therapy for advanced cancer
This trial tests a new treatment that combines a special type of focused ultrasound (called histotripsy) with an immune checkpoint inhibitor to boost the immune system's attack on cancer. It is for people with advanced cancer that has not responded to standard treatments.
Utrecht, UtrechtAges 18 years+ - NCT06601179Recruiting
HIFU ultrasound for enlarged prostate
This trial tests a focused ultrasound treatment for benign prostatic hyperplasia (BPH), which is a non-cancerous enlargement of the prostate. It aims to see if HIFU can safely relieve symptoms like weak urine flow and frequent urination.
BesançonAges 50–85 - NCT06643767Recruiting
Testing a new breast exam device during mammogram
This study tests a new device called Bexa that examines the breast to see if it works well along with a standard mammogram. It may help find breast concerns more easily.
Abilene, TexasAges 30–75 - NCT06692335Recruiting
Comparing HIFU and surgery for uterine fibroids
This trial compares two treatments for painful or heavy menstrual bleeding caused by uterine fibroids: high-intensity focused ultrasound (HIFU) and myomectomy (surgery to remove fibroids). It may help you decide which option fits your needs.
Hong KongAges 18–50 - NCT07684976Recruiting
Safety of a helmet device using ultrasound for substance use disorder
This study tests a special helmet that uses focused ultrasound to stimulate parts of the brain involved in addiction. It aims to see if the treatment is safe and works for people with moderate to severe substance use disorder who have not gotten enough help from standard medication treatments.
Toronto, OntarioAges 18–70 - NCT07044973Recruiting
Focused ultrasound for Parkinson's disease tremor
This trial uses focused ultrasound to treat tremor and movement problems in Parkinson's disease. It targets a specific brain area without surgery, and may help if your symptoms are worse on one side and not fully controlled by medication.
Beijing, Beijing MunicipalityAges 22 years+ - NCT07094789Recruiting
Ultrasound therapy for stubborn depression
This trial tests whether a non-invasive ultrasound technique can help people whose depression has not improved with standard treatments. You would receive the ultrasound treatment while having MRI scans to see how your brain changes.
Toronto, OntarioAges 18–65 - NCT07108257Recruiting
Focused ultrasound for bipolar depression
This trial uses sound waves guided by MRI to target a small brain area. It aims to help people with bipolar depression that hasn't improved with standard treatments.
Toronto, OntarioAges 18–65 - NCT07113665RecruitingPhase 1
Focused ultrasound brain treatment for severe anorexia
This trial tests if focused ultrasound can help people with severe anorexia nervosa who also have obsessive-compulsive disorder or major depression. It is for those who have not gotten better with other treatments.
Toronto, OntarioAges 18–65 - NCT07164105Recruiting
Using low-intensity ultrasound to treat PTSD in healthcare workers
This study tests whether a new non-invasive brain treatment called low-intensity focused ultrasound (LIFU) can help reduce PTSD symptoms in healthcare workers. It aims to find out how the treatment works and if it is safe and effective.
Tulsa, OklahomaAges 18–65 - NCT07179419Recruiting
Long-term effects of HIFU for rectal endometriosis
This study checks how well High-Intensity Focused Ultrasound (HIFU) treatment works over time for people with rectal endometriosis. It's for those who already had HIFU in one of the earlier studies and want to help researchers understand long-term results.
LyonAges 18 years+ - NCT07184970Recruiting
Detecting prostate cancer return after HIFU with advanced scans
This trial uses a special PET/MRI scan to check if prostate cancer has come back after high-intensity focused ultrasound (HIFU) treatment. It aims to find any remaining cancer early so doctors can plan next steps.
New York, New YorkAges 40–95 - NCT07212244Recruiting
Focused ultrasound for hard-to-treat tremor
This study uses a focused ultrasound treatment guided by MRI to calm hand tremors in people with essential tremor that hasn't responded to medication. It aims to improve daily life by reducing shaking without the need for surgery.
Toronto, OntarioAges 22 years+ - NCT07229430Recruiting
Ultrasound treatment for loose neck and chin skin
This study tests a high-intensity focused ultrasound (HIFU) device to lift and tighten loose skin under the chin and neck. If you are in good health and want a non-surgical option for mild to moderate skin laxity, this trial may be for you.
Los Angeles, CaliforniaAges 30–65 - NCT07680842Recruiting
Non-invasive ultrasound for drug-resistant epilepsy
This study tests a non-invasive focused ultrasound treatment for people with epilepsy that doesn't respond to medications. The goal is to see if this gentle ultrasound can reduce seizures without surgery.
San Francisco, CaliforniaAges 21–65 - NCT07284719Recruiting
Focused Ultrasound for Parkinson's Tremor
This trial tests a non-invasive treatment called MR-guided focused ultrasound (MRgFUS) to reduce severe tremor in Parkinson's disease. It uses sound waves to target the brain area causing the shaking, without surgery.
AarhusAges 50–80 - NCT07394387RecruitingPhase 2
HIFU with or without immunotherapy before chemo for triple-negative breast cancer
This trial tests whether adding focused ultrasound (HIFU) and an immunotherapy drug (PD-1 inhibitor) before standard chemotherapy can improve outcomes for women with stage II or III triple-negative breast cancer (TNBC). It aims to find a more effective way to shrink tumors before surgery.
Nanjing, JiangsuAges 18–70 - NCT01194648Recruiting
HIFU treatment for early prostate cancer
This trial studies a focused ultrasound treatment called HIFU for prostate cancer that appears limited to the early stages. It aims to treat cancer within the prostate while avoiding treatment spread to lymph nodes or distant organs.
London, EnglandAges Up to 90 years
Hear when a new Focused Ultrasound trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for focused ultrasound?
- Yes. Clin2 currently lists 104 recruiting focused ultrasound studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a focused ultrasound trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a focused ultrasound trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.