Clinical trials
Focused Ultrasound clinical trials
Below are recruiting focused ultrasound clinical trials, each written for real people, not researchers. We’re tracking 113 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06524570RecruitingPhase 1
Focused ultrasound plus immune therapy for advanced cancer
This trial tests a new treatment that combines a special type of focused ultrasound (called histotripsy) with an immune checkpoint inhibitor to boost the immune system's attack on cancer. It is for people with advanced cancer that has not responded to standard treatments.
Utrecht, UtrechtAges 18 years+ - NCT06492720Recruiting
Testing focused ultrasound for drug-resistant epilepsy
This study tests a new device called NaviFUS that uses focused sound waves to gently stimulate a small area of the brain. It is for people whose seizures start in one part of the brain and are not fully controlled by seizure medicines.
TaipeiAges 18–65 - NCT06474026Recruiting
Focused Ultrasound for Stimulant Use Disorder
This trial tests a non-invasive brain treatment called focused ultrasound for people with stimulant use disorder (like methamphetamine or cocaine). It aims to help reduce cravings and improve recovery by gently stimulating a brain area involved in addiction.
Seoul, SeoulAges 19–60 - NCT06388707RecruitingPhase 1/Phase 2
Ultrasound therapy for drug-resistant temporal lobe epilepsy
This study tests if a new, non-invasive ultrasound treatment can safely reduce seizures in people whose seizures start in the temporal lobe and have not been controlled by at least two anti-epileptic drugs. The ultrasound is delivered through the scalp to gently stimulate the brain area where the seizures begin.
Palo Alto, CaliforniaAges 18 years+ - NCT06331052Recruiting
Testing a new focused ultrasound treatment for essential tremor
This study is testing a new way to treat essential tremor using focused ultrasound waves guided by MRI to target the part of the brain causing the tremor. The goal is to see if it can reduce tremor without invasive surgery.
Chapel Hill, North CarolinaAges 22 years+ - NCT06178354Recruiting
Freezing or ultrasound for early prostate cancer
This trial is testing whether freezing (cryotherapy) or using high-frequency ultrasound (HIFU) to destroy only the cancer spots in the prostate is safe and effective for men with early-stage prostate cancer. It's a less invasive option that targets just the tumor, not the whole prostate.
Sacramento, CaliforniaAges 18 years+ - NCT06039709RecruitingPhase 1
Sound wave therapy for recurrent glioblastoma
This trial tests a new treatment called sonodynamic therapy that uses sound waves and a special drug to target brain tumors that have come back. It aims to see if this approach is safe and can shrink tumors in people who are eligible for surgery.
Charlottesville, VirginiaAges 18–80 - NCT05784805Recruiting
Focused ultrasound treatment during EEG monitoring for ongoing seizures
This trial tests whether a focused ultrasound treatment can change brain electrical activity seen on an EEG in people with ongoing seizure emergencies. It may help doctors learn safer ways to modulate seizure activity when standard medicines are not fully stopping it.
New Haven, ConnecticutAges 19–85 - NCT05762419RecruitingPhase 1
FUS and etoposide treatment for midline brain tumors
This early-phase study tests whether focusing ultrasound (FUS) plus etoposide can help treat children and teens with diffuse midline glioma that affects the brainstem (pons) and/or thalamus, especially with an H3K27M change. Participants must have cancer that is getting worse and be healthy enough to safely receive study treatment.
New York, New YorkAges 4–21 - NCT05565443Recruiting
Ultrasound plus GCase treatment for Parkinson’s symptoms
This trial studies whether MR-guided focused ultrasound combined with an enzyme treatment called GCase can improve Parkinson’s disease. It includes people with specific Parkinson’s diagnosis and scan findings, and it may help those with certain genetic or imaging markers.
Toronto, OntarioAges 35–80 - NCT05317858RecruitingPhase 3
Open the brain’s blood barrier to treat lung cancer brain spots
This trial tests whether using focused ultrasound to temporarily open the brain’s blood barrier—plus standard immune therapy—can better treat non-small cell lung cancer (NSCLC) that has spread to the brain. It aims to help medicines reach the brain tumor spots more effectively, while still using the usual lung cancer treatment.
Phoenix, ArizonaAges 18–100 - NCT05291507RecruitingEarly Phase 1
MRI-guided focused ultrasound for breast cancer during surgery
This early study tests whether a device that uses focused ultrasound (guided by MRI) can be safely used during surgery for women with invasive breast cancer. It mainly looks at feasibility—whether the treatment can be delivered as planned and is safe.
Salt Lake City, UtahAges 18 years+ - NCT05111964Recruiting
Ultrasound treatment for soft tissue sarcoma tumors
This trial tests a non-surgical ultrasound treatment (HIFU) that targets the tumor from the outside of the body. It may help by shrinking or controlling certain types of soft tissue sarcoma or desmoid tumors when they are hard to remove surgically or when surgery/chemo/radiation is not a good option.
Oxford, OxfordshireAges 18 years+ - NCT04557891Recruiting
Low-intensity ultrasound for generalized anxiety disorder
This trial tests a non-drug brain treatment using low-intensity focused ultrasound to reduce symptoms of generalized anxiety disorder (GAD). It may help if your anxiety has been moderate to severe and you’ve already tried standard medications without enough relief.
Los Angeles, CaliforniaAges 18–65 - NCT02151175Enrolling by invitation
Focused ultrasound to treat medication-resistant temporal lobe seizures
This trial tests a low-intensity focused ultrasound treatment aimed at reducing seizures caused by problems in one side of the hippocampus (a brain area involved in memory and seizures). It’s for people whose seizures have not responded to several seizure medicines and who have been offered a specific type of surgery.
Los Angeles, CaliforniaAges 18–60 - NCT05910567Recruiting
Ultrasound test for abdominal injuries in children after blunt trauma
This study looks at how well an abdominal ultrasound test (FAST) works for children who come to the emergency department after a serious blunt injury to the belly or torso. The goal is to help doctors find dangerous internal bleeding or organ injury quickly and safely.
Sacramento, CaliforniaAges Up to 17 years - NCT07800962Enrolling by invitation
Comparing bedside heart ultrasound to standard echocardiography
This study looks at whether a quick ultrasound done at the bedside (point-of-care) can give similar information to a full echocardiogram. Participants must be adults having both tests within 24 hours of each other, and their medical data must be available for research.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for focused ultrasound?
- Yes. Clin2 currently lists 113 recruiting focused ultrasound studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a focused ultrasound trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a focused ultrasound trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.