Clinical trials
Focused Ultrasound clinical trials
Below are recruiting focused ultrasound clinical trials, each written for real people, not researchers. We’re tracking 113 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07616440Recruiting
Ultrasound drug delivery with chemotherapy for HER2-positive breast cancer
This study tests a new technique that uses focused ultrasound to deliver cancer drugs directly to breast tumors, combined with standard chemotherapy. The goal is to improve treatment effectiveness for HER2-positive breast cancer before surgery.
Hangzhou, ZhejiangAges 18–70 - NCT03192436Recruiting
Safety study using brain mapping with focused ultrasound
This study tests the safety of a brain stimulation approach that uses special brain recording and “focused ultrasound” targeted by brain signals. It is designed for healthy adults and checks whether the procedure is tolerated without serious side effects.
Pittsburgh, PennsylvaniaAges 18–64 - NCT07518927Enrolling by invitation
Brain Mapping Study Using Ultrasound and Implanted Electrodes
This research study uses focused ultrasound waves combined with brain electrodes (already implanted for your epilepsy or psychiatric treatment) to map how your brain responds. The goal is to better understand brain function and potentially improve future treatments.
Philadelphia, PennsylvaniaAges 21–75 - NCT07220655Recruiting
How focused ultrasound affects thinking and brain activity
This trial uses low-intensity focused ultrasound (LIFU) and brain scans to see how it affects thinking. It may help researchers find new ways to treat brain conditions.
Minneapolis, MinnesotaAges 18 years+ - NCT07866768Recruiting
Ultrasound treatment to clear brain waste in early memory loss
This study tests a low-intensity ultrasound treatment aimed at helping the brain clear out harmful protein buildup linked to Alzheimer's disease. It is for people 65 and older with mild cognitive impairment (slight but noticeable memory problems) and a positive test for amyloid, a protein in the brain.
San Francisco, CaliforniaAges 65 years+ - NCT06820138RecruitingPhase 2
Focused ultrasound treatment for PTSD in veterans
This study tests a non-invasive treatment called focused ultrasound for veterans with PTSD. Focused ultrasound uses sound waves to target specific brain areas without surgery. It aims to reduce PTSD symptoms like distress and anxiety.
Providence, Rhode IslandAges 22–70 - NCT07161518Enrolling by invitationPhase 4
Testing focused ultrasound on the brain during sedation
This trial uses focused ultrasound to gently stimulate parts of the brain while you are under sedation. It aims to understand how this technology affects brain activity and could lead to new ways to treat brain disorders without surgery.
Palo Alto, CaliforniaAges 18–65 - NCT06518785Recruiting
Ultrasound brain treatment for alcohol use disorder
This study tests if focused ultrasound can help reduce alcohol cravings by stimulating a specific part of the brain. Participants will receive ultrasound treatments and undergo an MRI to see how the brain responds.
San Francisco, CaliforniaAges 18 years+ - NCT06185972RecruitingPhase 2
MRI-guided ultrasound radiation for breast and chest cancer
This trial tests a new way to give radiation therapy using MRI imaging and ultrasound to make the radiation more targeted and potentially safer. If you have chest-wall or breast cancer and are already scheduled for radiation, this approach might offer a more precise treatment option.
Toronto, OntarioAges 18 years+ - NCT07166289Recruiting
Ultrasound treatment for tough depression
This study uses focused ultrasound to stimulate brain circuits in people with treatment-resistant depression. It aims to see if this can help when other treatments haven't worked.
Tulsa, OklahomaAges 18–65 - NCT06633601RecruitingPhase 1
Ultrasound and microbubbles with radiation for breast cancer
This trial tests a new way to combine radiation therapy with ultrasound and tiny bubbles to treat breast cancer that has spread to the chest wall or is advanced. It aims to make radiation more effective and safer.
Toronto, OntarioAges 18 years+ - NCT06939348Recruiting
Ultrasound therapy for patients with consciousness disorders
This trial tests whether ultrasound stimulation can help people with disorders of consciousness, like coma or a minimally conscious state. It aims to improve brain function and recovery for patients who have been injured for over a month.
Los Angeles, CaliforniaAges 18–79 - NCT07796061RecruitingPhase 1
Ultrasound plus immune cells for brain tumors
This trial tests a new way to treat a type of brain tumor called diffuse midline glioma. It uses focused ultrasound to open a tiny gap in the blood-brain barrier, which may help special immune cells (T-cells) reach and attack the tumor. The goal is to see if this combination is safe and helpful.
Washington D.C., District of ColumbiaAges 3–25 - NCT01194648Recruiting
HIFU treatment for early prostate cancer
This trial studies a focused ultrasound treatment called HIFU for prostate cancer that appears limited to the early stages. It aims to treat cancer within the prostate while avoiding treatment spread to lymph nodes or distant organs.
London, EnglandAges Up to 90 years - NCT05500118Recruiting
Decision help tool for symptom-free fibroids treated with HIFU
This study is testing a decision-making tool to help doctors choose the best care for women with small fibroids that cause no symptoms. It also looks at factors that may affect outcomes when using HIFU, a non-surgical treatment that heats tissue with focused ultrasound.
Shenzhen, GuangdongAges 18–55 - NCT07802431Recruiting
Body contouring treatment for belly and love handles
This trial tests a new non-invasive device to reduce fat in the belly and sides (love handles). It may help people who have stubborn fat in these areas despite a stable weight.
Nuevo León, MonterreyAges 18–65 - NCT07757490Recruiting
Sonablate HIFU registry for prostate cancer and BPH
This study is a registry that collects information from men who have had Sonablate HIFU treatment for prostate cancer or enlarged prostate (BPH). It will help doctors learn more about how well this treatment works in real life.
Indianapolis, IndianaAges 18 years+ - NCT07728994RecruitingPhase 2
Focused ultrasound for OCD treatment study
This trial tests if focused ultrasound can help treat OCD. If you join, you'll wear a special device during sessions and have an MRI scan.
San Francisco, CaliforniaAges 22–80 - NCT06601179Recruiting
HIFU ultrasound for enlarged prostate
This trial tests a focused ultrasound treatment for benign prostatic hyperplasia (BPH), which is a non-cancerous enlargement of the prostate. It aims to see if HIFU can safely relieve symptoms like weak urine flow and frequent urination.
BesançonAges 50–85 - NCT06643767Recruiting
Testing a new breast exam device during mammogram
This study tests a new device called Bexa that examines the breast to see if it works well along with a standard mammogram. It may help find breast concerns more easily.
Abilene, TexasAges 30–75 - NCT07691918Enrolling by invitation
Brain stimulation for mild memory loss
This trial tests if a non-invasive brain stimulation technique can help people with mild memory problems. It uses a special cap to gently stimulate the brain and aims to improve thinking and memory.
Roanoke, VirginiaAges 55–80 - NCT07690514Recruiting
Ultrasound treatment for cervical dystonia
This study tests a new type of ultrasound treatment for cervical dystonia (neck muscle spasms). It uses focused sound waves to target the brain areas causing the condition, and aims to see if it can reduce symptoms without surgery.
Toronto, OntarioAges 18–90 - NCT07680842Recruiting
Non-invasive ultrasound for drug-resistant epilepsy
This study tests a non-invasive focused ultrasound treatment for people with epilepsy that doesn't respond to medications. The goal is to see if this gentle ultrasound can reduce seizures without surgery.
San Francisco, CaliforniaAges 21–65 - NCT07684976Recruiting
Safety of a helmet device using ultrasound for substance use disorder
This study tests a special helmet that uses focused ultrasound to stimulate parts of the brain involved in addiction. It aims to see if the treatment is safe and works for people with moderate to severe substance use disorder who have not gotten enough help from standard medication treatments.
Toronto, OntarioAges 18–70
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Common questions
- Are there clinical trials for focused ultrasound?
- Yes. Clin2 currently lists 113 recruiting focused ultrasound studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a focused ultrasound trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a focused ultrasound trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.