Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 265 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06208527RecruitingPhase 2
Nicotinamide Riboside for Frailty in Older Adults
This trial tests whether a daily supplement called nicotinamide riboside can help older adults who feel weak or frail to get stronger and more energetic. It lasts for several months and involves simple tests like a walking test and memory checks.
Bergen, VestlandAges 75 years+ - NCT06267378Recruiting
Frailty and its effects on older patients having major gut surgery
This study looks at how frailty affects recovery and outcomes for patients aged 70 and older who are having planned surgery to remove colorectal cancer. The goal is to better understand frailty's impact so care can be improved.
Doncaster, South YorkshireAges 18 years+ - NCT06281275Recruiting
Frailty and pain after chest surgery in older adults
This study looks at how frailty affects pain after chest surgery in patients aged 60 and older. It uses a special pain pump and may help doctors better manage recovery for older adults.
Wuhan, HubeiAges 60 years+ - NCT06298877Recruiting
Stoma reversal and quality of life in ovarian cancer
This study looks at how temporary stoma (a surgical opening in the belly) affects quality of life and recovery in women having surgery for ovarian cancer. It may help doctors decide when to reverse the stoma so you heal better.
Stockholm, SolnaAges 18 years+ - NCT06373471Recruiting
Geriatric assessment for older frail adults with blood cancer
This trial tests whether a special check-up (called a geriatric assessment) can improve quality of life for older adults with blood cancer who are also frail. The goal is to help you feel better and manage treatments more effectively.
Odense CAges 70 years+ - NCT06404970Recruiting
A study for older veterans with frailty in primary care
This study aims to help identify and manage functional impairment and frailty in older veterans. It will test ways to improve how primary care providers screen and support veterans who may have difficulty with daily activities or overall health declines.
Philadelphia, PennsylvaniaAges 60 years+ - NCT06444321Recruiting
Integrated care for frail patients with heart failure
This trial tests a special care program for people with both frailty (being weak or vulnerable) and heart failure (when the heart doesn't pump well). The program brings together different types of support to help you manage your health better after a hospital stay.
Drammen, AkershusAges 18 years+ - NCT06527742Recruiting
Body health and recovery during rehabilitation
This study looks at how body composition, frailty, and function change during rehabilitation. It may help understand recovery patterns.
Singapore, SingaporeAges 21 years+ - NCT06604104Recruiting
Visual Frailty Study in Older Adults with AMD
This study looks at something called 'visual frailty' in older adults with advanced age-related macular degeneration (AMD). It aims to develop a tool to better understand how vision loss affects daily life and overall health in people aged 60 and over.
Edinburgh, ScotlandAges 60 years+ - NCT06614478Recruiting
Frailty, hip fractures and inflammation study
This study looks at how frailty and inflammation affect recovery after a hip fracture in older adults. It aims to find biomarkers that could help personalize care.
Larissa, ThessalyAges 65 years+ - NCT06693271Recruiting
Protein, blueberries, and exercise for heart health in older adults
This trial tests whether adding protein powder, blueberries, and a gentle exercise program together can improve heart health and reduce frailty in people 65 and older.
Halifax, Nova ScotiaAges 65 years+ - NCT06700291Recruiting
Frailty and thinking problems after surgery in older adults
This study looks at how frailty (a state of being physically weak and less resilient) before hip or knee replacement surgery affects thinking and memory problems after surgery in older adults. It aims to help identify patients who may need extra support.
TbilisiAges 65 years+ - NCT06810661Recruiting
Mobilizing patients with heart disease to reduce frailty
This study tests whether a gentle movement program helps people with heart disease stay stronger and more independent during their hospital stay. If you are staying in a specific unit at the Vitalité Health Network and have a heart condition, you may be able to join.
Moncton, New BrunswickAges 18 years+ - NCT06854731Recruiting
Preventing falls in older adults with memory concerns
This study tests a program to help older adults with mild memory problems and a recent fall improve their balance and prevent future falls. If you've had a fall in the past year and have some trouble with memory, this trial may offer safe exercises and guidance.
Vancouver, British ColumbiaAges 65–89 - NCT06965972Recruiting
Study of frailty and dependence in older adults
This study follows older adults to understand frailty and dependence over time. It may help improve care for people your age.
Barcelona, CataloniaAges 65–120 - NCT07004595Recruiting
Frailty in scarring lung disease: a study
This study looks at how frailty (a state of being more vulnerable to health problems) affects people with scarring lung diseases. It aims to understand if frailty can help predict how the disease will progress and how treatments might be adjusted.
Nantes, NantesAges 65 years+ - NCT07081282Recruiting
Study on frailty and thinking decline in older adults
This study looks at how to better understand and predict frailty and memory changes in older adults with at least one chronic condition. It aims to use a simple screening to personalize care and help you stay independent longer.
SingaporeAges 60–85 - NCT07109596Recruiting
Frailty prediction for older hospital patients
This study looks at how different factors—like health, mental well-being, and social support—work together to predict frailty in older adults. The goal is to better understand frailty in men and women, which may help doctors provide more personalized care.
RomaAges 56 years+ - NCT05977556Recruiting
Prehabilitation before surgery for older, frail adults
This study tests a 'prehabilitation' program — gentle exercise and health support before surgery — to see if it can help older adults feel stronger and less frail before going into a planned operation. It is for people 50+ who are a bit frail but can still walk.
EdmontonAges 50 years+ - NCT07379099Recruiting
Personalized Care Plan for ICOPE Program Graduates
This study tests a personalized care plan for people 60 and older who have finished Step 2 of the ICOPE program. It aims to see if this plan helps improve your health and independence.
ToulouseAges 60 years+ - NCT07469761Recruiting
Personalized care plan for frail cancer patients
This trial tests a special care plan designed for people with advanced cancer who are frail. The goal is to see if this personalized approach helps improve quality of life and support.
Milan, LombardyAges 18 years+ - NCT07477561Recruiting
Healthy aging program for older adults in Singapore
This trial tests a program to help older adults stay independent and prevent frailty. It is based on the World Health Organization's ICOPE approach and is designed for Singaporeans and permanent residents aged 60 and older.
SingaporeAges 60 years+ - NCT07481188Recruiting
Predicting survival after hip fracture with frailty and a score
This study looks at whether a simple score (Nottingham Hip Fracture Score) and a frailty check can help predict survival after hip fracture surgery. It aims to help doctors better understand risks for older adults who need hip surgery.
EdirneAges 60 years+ - NCT07519603Recruiting
Exercise program for older adults with COPD and frailty
This study tests whether a structured exercise and training program called VIVIFRAIL can help older adults with COPD feel stronger and more independent. You'll participate in guided physical activities designed to improve your strength and daily functioning.
Hanoi, HanoiAges 60 years+
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Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 265 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.