Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07029243Recruiting
Prehabilitation and supplement for frail cirrhosis patients
This study tests whether a prehabilitation program (exercise and nutrition planning) along with a supplement containing creatine and whey protein can help improve strength and well-being in people with cirrhosis who are frail. The goal is to see if this combination can help you feel stronger and more active.
San Francisco, CaliforniaAges 18 years+ - NCT07004595Recruiting
Frailty in scarring lung disease: a study
This study looks at how frailty (a state of being more vulnerable to health problems) affects people with scarring lung diseases. It aims to understand if frailty can help predict how the disease will progress and how treatments might be adjusted.
Nantes, NantesAges 65 years+ - NCT05946174Recruiting
Personalized frailty program for older people with heart frailty
This trial aims to adjust frailty-support activities for people who are physically vulnerable because of heart problems. It may help by creating a plan tailored to your needs, while carefully checking health issues that could make participation unsafe.
SingaporeAges 21–100 - NCT05993754Recruiting
Preventing confusion after surgery in frail older adults
This study tests whether a special nursing care plan can help prevent confusion after surgery in older adults who are frail. If you are 65 or older, having planned surgery, and generally healthy enough, this trial may be an option.
Santiago, Santiago MetropolitanAges 65 years+ - NCT06891573Recruiting
Lifestyle trial to prevent frailty and aging-related diseases
This study tests whether a lifestyle intervention can help prevent frailty and age-related health problems. If you are between 60 and 90 years old, have some signs of frailty, and can use a mobile app with help, you may be able to join.
IncheonAges 60–90 - NCT06854731Recruiting
Preventing falls in older adults with cognitive frailty
This trial studies a program to help older adults with mild memory problems and physical frailty reduce their risk of falling. It tests a home-based exercise and fall-prevention plan to improve strength and balance.
Vancouver, British ColumbiaAges 65–89 - NCT03824106Recruiting
Frailty rehab program for older adults at YMCA
This trial studies a rehabilitation (rehab) program to help older adults who are at risk of losing mobility and independence. You may be offered group-based rehab at the YMCA if you meet age, mobility, safety, and participation requirements.
Hamilton, OntarioAges 65 years+ - NCT06810661Recruiting
Mobilizing patients with heart disease to reduce frailty
This study tests whether a gentle movement program helps people with heart disease stay stronger and more independent during their hospital stay. If you are staying in a specific unit at the Vitalité Health Network and have a heart condition, you may be able to join.
Moncton, New BrunswickAges 18 years+ - NCT06802289Recruiting
Preventing frailty by keeping seniors active in the hospital
This trial tests whether a mobility program helps older adults stay strong and avoid frailty during a hospital stay. If you are 50 or older and expect to be in the hospital for at least 3 days, this study may offer extra support to keep you moving.
Moncton, New BrunswickAges 50 years+ - NCT05292989Recruiting
Using a frailty checklist to help older people choose care
This study looks at how a personalized “frailty” checklist can help older adults (65+) understand their health and make better choices. You may be asked to complete questionnaires and a frailty-type assessment to see if the approach works for you.
Woolloongabba, QueenslandAges 65–100 - NCT05922202Recruiting
Studying how frailty affects outcomes in COPD
This study looks at whether frailty (how weak or vulnerable someone is) changes the risk of heart-related events and death in people with COPD. It may help doctors better predict who is at higher risk and tailor care.
ModenaAges 40 years+ - NCT06700291Recruiting
Frailty and thinking problems after surgery in older adults
This study looks at how frailty (a state of being physically weak and less resilient) before hip or knee replacement surgery affects thinking and memory problems after surgery in older adults. It aims to help identify patients who may need extra support.
TbilisiAges 65 years+ - NCT06693271Recruiting
Protein, blueberries, and exercise for heart health in older adults
This trial tests whether adding protein powder, blueberries, and a gentle exercise program together can improve heart health and reduce frailty in people 65 and older.
Halifax, Nova ScotiaAges 65 years+ - NCT06604104Recruiting
Visual Frailty Study in Older Adults with AMD
This study looks at something called 'visual frailty' in older adults with advanced age-related macular degeneration (AMD). It aims to develop a tool to better understand how vision loss affects daily life and overall health in people aged 60 and over.
Edinburgh, ScotlandAges 60 years+ - NCT06614478Recruiting
Frailty, hip fractures and inflammation study
This study looks at how frailty and inflammation affect recovery after a hip fracture in older adults. It aims to find biomarkers that could help personalize care.
Larissa, ThessalyAges 65 years+ - NCT06570109Enrolling by invitation
Risk and outcomes of frailty in Alzheimer's dementia
This study looks at how frailty affects people newly diagnosed with Alzheimer's dementia. It aims to understand risk factors and outcomes to help improve care.
AalborgAges 65 years+ - NCT06507527Recruiting
Frailty in older adults having outpatient digestive endoscopy
This study looks at frailty in older adults (70+) who are having an outpatient digestive endoscopy. It aims to understand how frailty affects the procedure and recovery.
BarcelonaAges 70–100 - NCT06404970Recruiting
A study for older veterans with frailty in primary care
This study aims to help identify and manage functional impairment and frailty in older veterans. It will test ways to improve how primary care providers screen and support veterans who may have difficulty with daily activities or overall health declines.
Philadelphia, PennsylvaniaAges 60 years+ - NCT06298877Recruiting
Stoma reversal and quality of life in ovarian cancer
This study looks at how temporary stoma (a surgical opening in the belly) affects quality of life and recovery in women having surgery for ovarian cancer. It may help doctors decide when to reverse the stoma so you heal better.
Stockholm, SolnaAges 18 years+ - NCT05078957Recruiting
Study gut microbiome in older adults with well-controlled HIV
This trial studies how the bacteria in your gut (“microbiome”) relate to frailty (weakness/low physical resilience) in people with HIV who are stably doing well on treatment. It may help researchers understand why some people become frail and how the gut may play a role.
MarseilleAges 55 years+ - NCT06099912Recruiting
Personalized frailty-based treatment for older adults with new multiple myeloma
This trial tests a personalized treatment approach for people aged 65 and older with newly diagnosed multiple myeloma. The goal is to tailor therapy based on each patient's level of frailty, which could help improve outcomes and reduce side effects.
Changchun, JilinAges 65 years+ - NCT05928767Recruiting
Using frailty scores to predict death in ICU sepsis
This trial checks whether a “frailty” rating (how physically/mentally vulnerable someone is) can predict the risk of death in ICU patients with sepsis shock. It may help doctors identify higher-risk patients earlier and tailor care.
BéthuneAges 18–65 - NCT05625204Recruiting
HIIT exercise program to improve frailty in older veterans
This trial tests a high-intensity interval training (HIIT) exercise program to help older veterans feel stronger and more resilient and to reduce frailty. It may help people who are not yet very frail (or are just starting to become frail) but can safely exercise.
Kansas City, MissouriAges 65 years+ - NCT05257954Recruiting
Testing frailty in people getting a left atrial appendage closure
This study looks at frailty (how strong or vulnerable a person is) in adults who are having a left atrial appendage closure procedure through a catheter. The goal is to understand which patients may be more vulnerable during or after the procedure.
Québec, QuebecAges 18 years+
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Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 245 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.