Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 265 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07605936Recruiting
Understanding Frailty in Older Men With Prostate Cancer
This study looks at how frailty (physical weakness and loss of strength) affects older men who have been diagnosed with prostate cancer. Researchers want to understand which men are at higher risk and how this might guide better treatment decisions.
Limerick, MunsterAges 65 years+ - NCT07624370Enrolling by invitation
Frailty Assessment in Older Adults with Cancer
This study evaluates how to better assess and manage frailty (age-related weakness and vulnerability) in older cancer patients aged 70 and up who are starting chemotherapy or other cancer treatments. The goal is to help doctors tailor treatment plans to each patient's individual strength and health status.
Legnano, ItalyAges 70 years+ - NCT07616219Enrolling by invitation
Tai Chi Exercise Game for Muscle Weakness and Frailty
This trial tests whether playing an interactive Tai Chi exercise game can help older adults prevent muscle loss and frailty. You'll do gentle Tai Chi movements guided by a video game while standing, which may help you stay stronger and more independent.
Ho Man Tin, KowloonAges 60 years+ - NCT07176455Enrolling by invitation
Dietary habits after stomach cancer surgery
This trial studies how older stomach cancer survivors' eating habits change after surgery and tests ways to help them eat healthier. It focuses on people who just had their stomach cancer removed.
NanjingAges 60 years+ - NCT06570109Enrolling by invitation
Risk and outcomes of frailty in Alzheimer's dementia
This study looks at how frailty affects people newly diagnosed with Alzheimer's dementia. It aims to understand risk factors and outcomes to help improve care.
AalborgAges 65 years+ - NCT03995342Enrolling by invitation
Study gut bacteria and frailty in older adults
This study looks at whether gut bacteria (intestinal flora) are linked to frailty in people age 65 and older. It will also test an intervention to see if changing gut bacteria can help reduce frailty.
Xi'an, ShaanxiAges 65 years+ - NCT06849557Recruiting
Chair exercises for frail older adults in nursing homes
This trial tests if chair-based video games (exergaming) can help improve strength and mobility in older adults who are frail or pre-frail and live in nursing homes. It is designed for people who can sit on a chair or wheelchair without help.
KowloonAges 60 years+ - NCT06749080Recruiting
Assist 2.0: a program for healthy ageing at home
This trial tests a program called ASSIST 2.0 to help older adults stay active and independent at home. If you receive homecare, this program might help you manage daily tasks and improve your quality of life.
Huddinge, SwedenAges 65 years+ - NCT06611228Recruiting
Preventing disability in older hospital patients
This study tests if a program designed for older, frail hospital patients can prevent loss of ability to do daily tasks. It focuses on physical activity, mental engagement, and nutrition to help you stay independent.
Monza, LumbardyAges 70 years+ - NCT05946109Recruiting
Exercise program for frail older adults over 70
This trial studies whether a structured exercise program can improve health and function in frail adults age 70 and older. It may help you build strength, energy, and mobility if you meet frailty and safety requirements.
Brussels, Brussels CapitalAges 70 years+ - NCT06687291Recruiting
Thinking and memory after stomach or esophagus cancer surgery
This study looks at how surgery and chemotherapy for stomach or esophageal cancer may affect your thinking, memory, and other cognitive functions. Researchers want to understand these changes to better support patients.
HuddingeAges 18 years+ - NCT06359652Recruiting
Get Fit for Function: Exercise before lung surgery
This study tests a program to help you get stronger before lung surgery. It may improve your recovery after the operation.
Chicago, IllinoisAges 18 years+ - NCT06271239Recruiting
Exercise Program for Older Adults
This study tests a gentle exercise program called VIVIFRAIL® to help older adults stay strong and active. You'll do simple movements in a group setting designed to improve balance and strength.
Porto Alegre, Rio Grande do SulAges 60 years+ - NCT04173715Recruiting
Study measuring movement and behavior in older adults
This study checks how well you move and how you behave during simple tasks. It may help researchers understand physical function and activity patterns in older adults.
ToledoAges 65 years+ - NCT04094428Recruiting
Study of ICU outcomes, deaths, and care costs
This study looks at what happens to people in intensive care, including deaths and hospital resource use. It may help hospitals plan better care and understand the costs of staying in the ICU.
UlmAges Any age - NCT06286891Recruiting
Frailty and lung function after pulmonary endarterectomy
This study looks at how frailty, physical ability, and lung function change in people who have had surgery to remove blood clots from the lungs (pulmonary endarterectomy). It aims to help doctors better understand recovery after this procedure.
São Paulo, São PauloAges 18 years+ - NCT06025240Recruiting
Better antibody monitoring after kidney transplant
This study tests a new way to monitor harmful antibodies after a kidney transplant. It may help prevent transplant rejection over time.
Liverpool, MerseysideAges 18 years+ - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT05617196Recruiting
Virtual pre-surgery rehab for TAVI clinic patients
This study tests a virtual “prehab” program (coaching and preparation before a TAVI heart valve procedure) for people getting treated at the TAVI clinic. It may help you get ready better for the procedure and recovery using phone or online support.
Halifax, Nova ScotiaAges 50–100 - NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+ - NCT04954690Recruiting
Exercise program after kidney transplant for older adults
This trial tests a structured, coached exercise program for people who recently received a living-donor kidney and are coming from dialysis. It may help improve strength and daily function after transplant, especially if starting fitness is difficult.
San Francisco, CaliforniaAges 50 years+ - NCT05598112RecruitingEarly Phase 1
Oral stool-based microbiome treatment for healthy aging
This early-stage study tests whether changing the gut bacteria using an oral stool-based treatment (called oral FMT) can improve health in older adults. It aims to see if this approach affects aging-related changes, including gut and body function.
Beijing, Beijing MunicipalityAges 70–85 - NCT06345625Recruiting
Balance and walking with head movement in older adults
This study looks at how older adults keep their balance and walk when their head is moving. You may be asked to stand or walk while your head gently moves, so researchers can understand how your body reacts.
AntwerpAges 65–100 - NCT07642765Recruiting
Frailty Score and Blood Pressure Changes During Surgery
This study looks at a simple scoring system (EASIX) that predicts whether older or frail patients will experience dangerous blood pressure drops when anesthesia is given before surgery. Understanding this risk might help doctors better protect vulnerable patients during their operations.
KonyaAges 18 years+
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Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 265 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.