Clinical trials
Frailty clinical trials
Below are recruiting frailty clinical trials, each written for real people, not researchers. We’re tracking 245 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05091645Recruiting
Testing a Greek version of a frailty screening for hip fracture patients
This trial checks whether a translated and culturally adapted questionnaire (called the Groningen Frailty Indicator) works well for people age 65+ who have a hip fracture and are having surgery. It may help care teams better understand frailty and plan support after surgery.
LarissaAges 65 years+ - NCT03680677Recruiting
Checking frailty to guide treatment in older blood cancer patients
This study checks “frailty” (how strong and able you are to function) to help choose better treatment for people age 60+ with certain blood cancers like acute leukemia or MDS. It may help clinicians tailor care before major treatments like transplant or CAR T-cell therapy.
Philadelphia, PennsylvaniaAges 60 years+ - NCT03458429Enrolling by invitationPhase 1/Phase 2
Plasma from healthy donors for frailty and immune health
This Phase 1/2 study tests whether transfusions of donated plasma can improve frailty and immune function in older adults. It mainly checks safety first, and also looks for signs that the immune system and overall strength may improve.
Boynton Beach, FloridaAges 55–95 - NCT04027244Recruiting
Studying care plans for severe leg blood flow problems
This study looks at how best to manage severe leg ischaemia, a condition where blood flow to the leg is dangerously reduced. It mainly involves patients who are planning an intervention, and some participants may also do special heart imaging tests.
Leicester, LeicestershireAges 18–110 - NCT05074732Recruiting
Study of forensic mental health admissions after a service move
This study looks at all adult admissions to Ireland’s National Forensic Mental Health Service during a specific time window. It may help improve how the new forensic service at Portrane runs in the future.
DublinAges 18 years+ - NCT04767945Recruiting
Cirrhosis patient hospital registry
This study keeps a record of people who have liver cirrhosis and were admitted to the hospital after a worsening event. It may help doctors better understand what leads to hospital stays and improve future care.
Banská BystricaAges 19 years+ - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT03209414Recruiting
Study of frailty in heart patients receiving heart care
This trial looks at “frailty,” meaning reduced strength and resilience, in older adults with coronary artery disease who are getting heart care. It may help doctors better understand which patients are more at risk and how care decisions could be improved.
Zabrze, Upper SilesiaAges 65 years+ - NCT05810701Recruiting
Geriatric screening for newly diagnosed ovarian cancer patients
This study looks at older adults with newly diagnosed epithelial ovarian cancer and checks health factors that can affect treatment, like day-to-day function and support needs. It may help doctors choose better care plans for older patients by understanding risks and needs early.
Odense, Region of South DenmarkAges 70–120 - NCT05734300Recruiting
Surgery study for older adults with early colon cancer
This study looks at how well a planned surgery approach works for people age 75 and older with early-stage colon cancer. It may help improve outcomes by selecting the right patients for a specific colon operation plan.
Copenhagen, HerlevAges 65 years+ - NCT03413683Recruiting
Studying frailty in older adults living with HIV
This study looks at frailty (feeling weak, having trouble with daily activities, or losing strength) in people age 50 and older who are living with HIV. It may help researchers understand frailty in HIV and how to better support older adults.
ShatinAges 50 years+ - NCT04954690Recruiting
Exercise program after kidney transplant for older adults
This trial tests a structured, coached exercise program for people who recently received a living-donor kidney and are coming from dialysis. It may help improve strength and daily function after transplant, especially if starting fitness is difficult.
San Francisco, CaliforniaAges 50 years+ - NCT06104696Recruiting
Comprehensive Geriatric Assessment in Kidney Transplant Patients Over 60
This study looks at how a full health review (geriatric assessment) can help older adults who are getting or have gotten a new kidney. It aims to improve care and outcomes for patients aged 60 and over.
PragueAges 60 years+ - NCT06379009Recruiting
Home exercise program for kidney transplant recipients
This trial tests a home-based exercise program for people who have recently had a kidney transplant. It aims to help you improve your physical function and recovery after surgery.
OsloAges 18 years+ - NCT04173715Recruiting
Study measuring movement and behavior in older adults
This study checks how well you move and how you behave during simple tasks. It may help researchers understand physical function and activity patterns in older adults.
ToledoAges 65 years+ - NCT06345625Recruiting
Balance and walking with head movement in older adults
This study looks at how older adults keep their balance and walk when their head is moving. You may be asked to stand or walk while your head gently moves, so researchers can understand how your body reacts.
AntwerpAges 65–100 - NCT04615065Recruiting
Biobank study collecting emergency data for very sick patients
This study collects health and sometimes blood sample information from people arriving at the emergency department with high-risk or serious conditions. The goal is to build a large emergency “biobank” to help researchers better understand and improve urgent care.
GroningenAges 18 years+ - NCT07829484Recruiting
Exercise and olive oil for fall prevention in older adults
This study tests whether a home exercise program combined with daily extra virgin olive oil can reduce the risk of falls in older adults who are frail or at high risk of falling. It may help improve strength, balance, and overall health.
Pamplona, NavarreAges 75 years+ - NCT07828847Recruiting
Exercise and muscle health in older adults with diabetes
This study looks at how exercise affects muscle cell function in older adults with type 2 diabetes and frailty. It may help find ways to improve strength and independence in aging.
ValenciaAges 18–83 - NCT07808619Recruiting
AI health data study for adults
This study is collecting health data to train an AI system that may help predict or improve health outcomes. By joining, you help develop technology that could benefit patients in the future.
Boulder, ColoradoAges 18 years+ - NCT06471621Recruiting
Personalized care to prevent kidney injury after heart surgery
This trial tests whether personalized care can prevent acute kidney injury (sudden kidney damage) after heart or major blood vessel surgery. If you are having planned heart valve repair, bypass, or aortic surgery, you may be able to join.
BernAges 18 years+ - NCT06025240Recruiting
Better antibody monitoring after kidney transplant
This study tests a new way to monitor harmful antibodies after a kidney transplant. It may help prevent transplant rejection over time.
Liverpool, MerseysideAges 18 years+ - NCT06130787Recruiting
Using your body's age to personalize CML treatment
This study looks at how your 'biological age' (how old your body seems) affects how well you do on targeted therapy for chronic myeloid leukemia. It aims to personalize your care by combining age and frailty information.
AnnecyAges 18 years+ - NCT07732530Recruiting
Acupoint Stimulation and Exercise for Pre-Frail Older Adults
This study tests whether combining acupoint stimulation (a type of pressure on specific body points) with exercise can help older adults who are starting to become frail. It aims to improve strength and daily function.
TainanAges 50 years+
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Common questions
- Are there clinical trials for frailty?
- Yes. Clin2 currently lists 245 recruiting frailty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a frailty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a frailty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.