Clinical trials
FTD clinical trials
Below are recruiting ftd clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06613204Recruiting
Support program for family caregivers of FTD patients
This study tests a behavior change program for family members caring for someone with frontotemporal degeneration (FTD). It aims to help caregivers manage upsetting behaviors and reduce stress.
Portland, OregonAges 18–100 - NCT06064890RecruitingPhase 1/Phase 2
Gene therapy trial for genetic frontotemporal dementia
This trial tests a new gene therapy called AVB-101 for people with a specific genetic cause of frontotemporal dementia (FTD). The therapy is given as a one-time injection into the brain to potentially slow or stop the disease.
Columbus, OhioAges 30–75 - NCT06595212Recruiting
Twins study on ALS and FTD with genetic and environmental focus
This study looks at twins where at least one has ALS (a nerve disease) or FTD (a brain disorder) to understand how genes and environment affect these conditions. It may help if you and your twin both want to join.
Modena, ItalyAges 18 years+ - NCT06563986RecruitingPhase 2
Combination therapy for advanced colorectal cancer in the liver
This trial tests a combination of two chemotherapy drugs (FTD and tipiracil), a targeted therapy (bevacizumab), and a radiation treatment (radioembolization) for people with colorectal cancer that has spread mainly to the liver and hasn't responded to other treatments. The goal is to see if this combination can shrink tumors and help control the cancer.
UtrechtAges 18 years+ - NCT06856850Recruiting
Biosignatures in ALS and FTD
This trial collects biological samples from people with ALS or frontotemporal dementia (FTD) to find new markers that could lead to better understanding and treatment. You may be able to participate if you have been diagnosed with either condition.
MilanAges 18 years+ - NCT07549412RecruitingPhase 3
New chemotherapy drugs for advanced colorectal cancer
This trial tests whether a new chemotherapy combination (precemtabart tocentecan, with or without bevacizumab) works better than a standard treatment for colorectal cancer that has spread and stopped responding to previous drugs. The goal is to find treatments that help people live longer with fewer side effects.
Lone Tree, ColoradoAges 18 years+ - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Birmingham, AlabamaAges 18 years+ - NCT03402919Recruiting
Brain and memory study for people with thinking changes
This study looks at memory and thinking changes using questionnaires, memory testing, and brain scans. It may help researchers better understand neurodegeneration and dementia and how these problems show up over time.
Calgary, AlbertaAges 50–90 - NCT04715399Recruiting
Research study collecting data for neurodegenerative diseases
This study collects health information from people with neurodegenerative diseases, some family members, and healthy controls to help researchers better understand these conditions. It may help future diagnosis and research, and participation may include noninvasive checks and other procedures depending on your situation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04946916Recruiting
Testing blood/brain marker levels and thinking problems in psychiatric illness
This study looks at neurofilament light (a brain/nerve injury marker) and how it relates to thinking and memory problems in people with certain psychiatric conditions. It may help researchers understand brain changes and cognitive impairment, which could guide better diagnosis in the future.
BronAges 45–80 - NCT05116943Recruiting
ALS and related brain disease biospecimen biobank
This study builds a blood and spinal fluid (lumbar puncture) sample library from people with ALS, ALS-FTD, or similar neurodegenerative diseases. Your samples help researchers study these conditions, even if you are not receiving a new treatment.
Jacksonville, FloridaAges 18 years+ - NCT05558709Recruiting
Test for thinking and behavior skills in neurodegenerative disease
This trial checks a new kind of paper-and-pen (or computer-based) test to better measure thinking and social/behavior skills in people with certain brain diseases. It may help researchers improve how these skills are tracked and understood over time.
ParisAges 18–90 - NCT06337578Recruiting
Telephone-based cognitive screening study
This study tests if a phone-based cognitive screening can effectively assess thinking and memory. It may help people who can't easily visit a clinic.
MilanAges 18–100 - NCT06604520RecruitingPhase 2
Vortioxetine for mood and thinking in frontotemporal dementia
This trial tests if vortioxetine, an antidepressant, can improve mood symptoms (like depression or anxiety) and thinking abilities in people with frontotemporal dementia (FTD). It also includes healthy volunteers for comparison.
Baltimore, MarylandAges 45 years+ - NCT06668610Recruiting
Brain stimulation study for mild memory problems
This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.
Caserta, ItalyAges 55–85 - NCT06803784Recruiting
Bioproducts in body fluids for early brain disease detection
This study is looking for proteins in blood and other body fluids that could help detect brain diseases like Parkinson's, Alzheimer's, and ALS early. It aims to improve diagnosis and future treatments.
Pozzilli, ItalyAges 20 years+ - NCT06891716RecruitingEarly Phase 1
PET imaging study for TDP-43 protein disorders
This study uses a special PET scan to detect TDP-43 protein buildup in the brain, which is linked to conditions like frontotemporal dementia and ALS. Healthy volunteers and people with TDP-43 disorders are invited to take part.
AmsterdamAges 40–70 - NCT07235111Recruiting
Studying biomarkers for neurodegenerative diseases
This study is looking for people with neurodegenerative diseases (like Alzheimer's, Parkinson's, ALS) to help researchers find new markers in the body that could help understand these conditions better and possibly lead to better treatments.
Genoa, GenoaAges 18 years+ - NCT07316413Recruiting
Repetitive TMS for frontotemporal degeneration
This trial tests whether repetitive transcranial magnetic stimulation (rTMS) can help people with frontotemporal lobar degeneration. It is a non-invasive brain stimulation technique that may improve symptoms.
Brescia, ItalyAges 18 years+ - NCT06051123Recruiting
Probiotics for ALS and related disorders
This trial tests whether probiotics (healthy bacteria) can help people with ALS. You'll take a probiotic or placebo daily for several months, and researchers will track your symptoms and gut health.
Fredericton, New BrunswickAges 18 years+ - NCT07505784Recruiting
Brain stimulation study for frontotemporal dementia
This study tests a non-invasive brain stimulation technique called tACS (transcranial alternating current stimulation) in people with frontotemporal dementia. The goal is to see if it can improve symptoms like behavior and language problems.
Brescia, BSAges 40 years+ - NCT07643363Recruiting
Brain Stimulation for Cognitive Impairment in Dementia
This study tests a new brain stimulation technique called temporal interference stimulation to help slow cognitive decline in people with Alzheimer's disease or frontotemporal dementia. Researchers will combine this stimulation with cognitive training to see if it improves memory and thinking skills.
Tianjin, Tianjin MunicipalityAges 45–85 - NCT07558785Enrolling by invitation
Testing speech and memory checks at home for early thinking problems
This study uses a video-based system at home to check your speech and memory, helping doctors spot thinking problems early using artificial intelligence. The goal is to see if this simple, at-home test can reliably catch early memory and thinking changes.
PilsenAges 40 years+ - NCT07314190Enrolling by invitation
Blood tests for brain diseases and mental health conditions
This study looks at blood tests to help diagnose and track brain diseases (like Alzheimer's) or mental health conditions. It compares patients to healthy volunteers to find better ways to detect and monitor these illnesses.
BarcelonaAges 18 years+
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Common questions
- Are there clinical trials for ftd?
- Yes. Clin2 currently lists 27 recruiting ftd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ftd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ftd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.