Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05895019Recruiting
Propofol’s effects on brain function in Parkinson’s surgery
This study tests how propofol, a common anesthesia medicine, affects brain activity in people with Parkinson’s disease during planned surgery. It also compares them with people without Parkinson’s during similar non-brain, non-heart surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT05851053Recruiting
Study of heart function years after breast cancer treatment
This study checks how well your heart works long after breast cancer treatment. If you joined the earlier de BLOC-I study, you may be invited for follow-up to understand long-term heart effects.
GroningenAges Any age - NCT05857774Recruiting
Study breathing muscle changes in ICU patients on ventilation
This study looks at how the muscles used for breathing work and change in ICU patients who are placed on breathing machines, then follows outcomes after they leave the hospital. It may help doctors better predict recovery and long-term health after ventilation.
Toronto, OntarioAges 18 years+ - NCT05858437Recruiting
Testing propionic acid to improve immune function in children with kidney failure
This study tests whether propionic acid can help the immune system work differently in children with advanced chronic kidney disease who receive regular dialysis. It may help regulate immune cells, aiming for better immune function while keeping you medically stable.
BerlinAges 12–20 - NCT05861999RecruitingPhase 4
Risdiplam for young children with SMA after gene therapy plateau
This trial studies whether risdiplam is safe and helpful for children under 2 with spinal muscular atrophy (SMA) whose function has leveled off or declined after gene therapy. It may be an option if you saw benefits from gene therapy but then noticed a stop or setback in key abilities.
Little Rock, ArkansasAges 3 months–2 years - NCT05865093Recruiting
Check early vision changes in infants at risk for brain vision problems
This pilot study looks at early vision (what babies can see and how their eyes respond) in children who have risk factors for future “cerebral visual impairment,” meaning vision problems caused by the brain. It may help doctors spot issues earlier and better understand which early visual signs matter.
RomeAges 2 days–3 years - NCT05866003Recruiting
Brain stimulation plus hand training after stroke
This trial tests whether a combination of brain stimulation and structured hand practice can improve hand movement for people recovering from stroke. It may help because the training targets upper-limb function while using therapy intended to support recovery.
Cleveland, OhioAges 21–90 - NCT05871216Recruiting
Study of joint instability in people with loose joints
This trial is testing how to assess and manage joint instability in people who have unusually loose (hypermobile) joints. If you have moderate to severe loose joints, you may be able to join after screening checks like movement tests and health history.
BolognaAges 18–60 - NCT05877846Recruiting
Personalized care to improve physical function in older adults
This study looks at precision (personalized) approaches to help older adults improve physical function. It may include giving a specific supplement depending on lab results, and it requires regular study visits and ability to complete procedures.
Chapel Hill, North CarolinaAges 65–85 - NCT05879276RecruitingPhase 3
Early empagliflozin for shock patients after ICU start
This trial studies whether starting empagliflozin early in adults with cardiogenic shock helps people live longer and have fewer hospital returns, while also checking heart pumping and kidney function. It may help some ICU patients, but eligibility is strict and depends on kidney function and prior medication use.
Ars-LaquenexyAges 18 years+ - NCT05884008Recruiting
Using CT heart scans and AI to study plaque function
This study looks at people who had a heart attack and had a special CT scan (CT angiography) before or during the years leading up to it. Researchers will use the scan and computer analysis (AI) to better understand heart plaque and how it may relate to heart attacks.
Cangzhou, HebeiAges 18–80 - NCT05884138Recruiting
Amino acid supplement and exercise for people on dialysis
This trial studies whether taking essential amino acids along with exercise can improve muscle function in people receiving hemodialysis. It may help you build or maintain strength and mobility.
Daejeon, South KoreaAges 20–80 - NCT05886725Recruiting
At-home walking test to help recovery after major surgery
This study looks at how a simple at-home walking pattern test, done before and after major surgery, relates to how older adults recover. It may help doctors better understand recovery and possibly tailor support after surgery.
Chicago, IllinoisAges 60 years+ - NCT05892133Recruiting
Exercise program before knee replacement to improve recovery
This trial studies whether doing a structured exercise or “prehab” program before total knee replacement can improve knee function and patient satisfaction after surgery. It may help you recover better and feel more confident in your outcome.
Molde, Møre og RomsdalAges 50–80 - NCT05893524Recruiting
Dementia and walking study using simple movement tests
This study looks at how memory problems and walking/mobility are connected. It may help researchers understand better ways to assess dementia risk and mobility changes early.
Falun, Dalarna CountyAges 37–94 - NCT05895344Recruiting
Compare proton vs modern radiation effects on thinking
This study compares two types of radiation—proton therapy versus modern fractionated radiation—to see how they affect long-term thinking (cognitive function) and daily abilities in people with a specific skull-base tumor. It may help clarify which radiation approach best protects brain and nerve function over time.
CaenAges 18–70 - NCT05899166Recruiting
Diet study to improve blood sugar control in new diabetes
This study looks at how carbohydrate intake may affect how well insulin-producing cells work and how stable your blood sugar becomes in children with newly diagnosed type 1 diabetes. It may help families learn dietary steps that improve glucose control early on.
Boston, MassachusettsAges 5–12 - NCT05899439Recruiting
Blood test study of immune changes in type 1 diabetes
This study looks at how your immune system changes over time and how that relates to developing type 1 diabetes. You may be able to join if you can have blood drawn, since the study focuses on blood samples.
Gainesville, FloridaAges birth–100 years - NCT05903859RecruitingPhase 3
Study to improve fertility in men after spinal cord injury
This phase 3 study tests a treatment to improve reproductive function (fertility-related measures) in men who have had a traumatic spinal cord injury. If you may be eligible, it could help researchers see whether the treatment improves reproductive outcomes for men with spinal cord injury.
Miami, FloridaAges 18 years+ - NCT05908591Recruiting
Pregnancy sleep study on breathing, blood vessel function, and safety
This study looks at how sleep and breathing changes during pregnancy may affect blood vessel function and pregnancy safety. You may be asked about your sleep and possibly have health checks during the middle of pregnancy.
Edmonton, AlbertaAges 18 years+ - NCT05909267Recruiting
Testing dopamine-targeted treatment for depression and body inflammation
This study looks at how changing dopamine signaling may affect motivation and movement in people with major depression, and it also involves healthy volunteers. It may help researchers understand whether dopamine changes can improve symptoms and how inflammation may relate to brain function.
SteglitzAges 18–65 - NCT05912257Recruiting
Nutrition program before and after surgery to protect function
This study tests whether an “optimizing nutrition” plan before and after cancer surgery can help older adults maintain physical strength and daily functioning. You may be randomly assigned to the nutrition program or another study group, and you’ll be asked about diet and physical function.
Durham, North CarolinaAges 55 years+ - NCT05920629Recruiting
Moderate drinking and heart recovery after a recent heart attack
This study looks at whether moderate alcohol intake affects heart function after a recent heart attack. You may be asked to follow a specific plan and attend scheduled visits so researchers can measure changes in your heart and overall recovery.
Basel, BaselAges 18 years+ - NCT05921422Recruiting
Study of thinking skills in children with cerebral palsy
This study looks at how children’s and teens’ thinking and learning work in everyday school life. It may help researchers better understand strengths and challenges in cerebral palsy to improve support.
CopenhagenAges 11–15
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.