Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05755919Recruiting
Brain mapping during epilepsy surgery with special brain electrodes
This study looks at how to map brain function in people having epilepsy surgery by recording brain signals using special electrodes placed on or inside the brain. It may help doctors better understand which brain areas cause seizures.
Detroit, MichiganAges 6 months–21 years - NCT05760924Recruiting
Testing a new heart pacing method for CRT nonresponders
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
TomskAges 18–80 - NCT05762952RecruitingPhase 1
Dapagliflozin study for heart micro-blood-flow symptoms in women
This early-phase study tests whether dapagliflozin can improve tiny blood-vessel function in women who have heart-ache-like symptoms but no major blockage on heart scans. If it works, it may help symptoms related to “microvascular” heart circulation problems.
Charlottesville, VirginiaAges 18–99 - NCT05765864Recruiting
Study of self-harm in at-risk teens
This study looks at self-harm and thoughts/behaviors related to safety in teenagers who are considered at higher risk. It may help researchers better understand what supports are needed for teens who self-harm without wanting to die.
LjubljanaAges 13–18 - NCT05769816RecruitingPhase 2
Combination treatment aimed to cure chronic hepatitis B
This Phase 2 study tests a combination therapy to help people with chronic hepatitis B reach a “functional cure,” meaning the hepatitis B surface antigen (HBsAg) is lost for a sustained period. If you qualify, you’ll be closely monitored to see how well the treatment works and whether it’s safe for you.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT05771402RecruitingPhase 2
Combination treatment aimed at clearing hepatitis B long-term
This Phase 2 study tests a combination treatment to help people with chronic hepatitis B stop having detectable hepatitis B surface antigen (called HBsAg). If successful, it may move you closer to a “functional cure,” meaning lower ongoing virus activity over time.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT05774262Recruiting
Pacemaker or nerve-targeting treatment for certain heart rhythm blocks
This study compares two treatments for specific “AV block” heart rhythm problems: a pacemaker versus a procedure called cardioneuroablation. The goal is to see which approach works better for preventing symptoms like fainting or slow heart rates.
Dąbrowa GórniczaAges 18–75 - NCT05788276RecruitingPhase 4
Dapagliflozin to help transplanted kidneys stay healthy
This study tests whether dapagliflozin can preserve the structure and function of a kidney transplant. You may be asked to take dapagliflozin on top of usual transplant medicines to see if it helps the new kidney work better over time.
Oslo, OsloAges 18–75 - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT05796401RecruitingPhase 3
Personalized care program for early psychosis outcomes
This trial tests whether a personalized care plan improves day-to-day functioning for people in the early stages of psychosis. It aims to see if adding structured support after a recent diagnosis can help you function better.
BrestAges 15–30 - NCT05799092Recruiting
Invasive vs non-invasive test for less-severe blocked heart arteries
This study compares two approaches to evaluating and treating people with symptoms of blocked heart arteries that are not “high-risk.” It may help doctors choose the safest, most effective next step for you by comparing invasive testing versus non-invasive evaluation.
Bucheon-siAges 19 years+ - NCT05800470Recruiting
Brain-training with light sensors to improve walking in Parkinson’s
This trial tests a “neurofeedback” training program using a special light-sensing cap (fNIRS) to help improve balance and walking in people with Parkinson’s disease. You may also do guided walking practice mentally (imagery training), and your ability to walk and balance will be measured.
Taipei, None SelectedAges 40–85 - NCT05802459Recruiting
Check how two bowel-reconstruction options affect daily life
This study looks at how surgeons rebuild the esophagus using either a jejunum (small intestine) or a colon (large intestine) piece, and how that affects your day-to-day function and quality of life. It may help doctors choose the approach that best supports recovery and independence for patients needing esophageal reconstruction.
BarcelonaAges 18 years+ - NCT05805202Recruiting
Study rare gene changes in atypical HUS for tailored care
This study looks at how rare gene mutations may explain atypical HUS (aHUS) and how that could guide more personalized treatment. It mainly involves people who have had aHUS affecting blood counts and kidneys.
Ranica, BGAges Any age - NCT05808920Recruiting
Salvage surgery study for recurrent head and neck skin-cell cancer
This study looks at how well people do after “salvage” surgery (planned surgery after prior treatment) for recurrent or residual squamous cell cancer in the head and neck. It may help doctors understand which patients benefit most, including how this surgery affects survival and day-to-day function.
DerbyAges 18 years+ - NCT05814497Recruiting
Brain scan study of how kids process chronic pain
This study looks at how the brain processes pain sensations in children with certain long-lasting pain conditions. It may help researchers understand what’s happening in the nervous system and guide better treatments.
Cincinnati, OhioAges 10–17 - NCT05817305Recruiting
Exercise program for people with past heart problems
This trial looks at adding regular exercise to everyday life for people who have had previous heart events. It aims to improve safety and day-to-day health by monitoring who can exercise safely.
Ferrara, FerraraAges 18 years+ - NCT05823727Recruiting
Collagen supplement study before and after knee replacement
This study tests whether taking collagen peptides can improve how knee tissues heal and remodel after total knee arthroplasty (knee replacement). It also looks at functional recovery and wound healing, especially during the physical therapy period in Little Rock.
Little Rock, ArkansasAges 50–75 - NCT05829668Recruiting
Behavior plan study for children with Cornelia de Lange syndrome
This study tests a structured behavior assessment and treatment program for children with Cornelia de Lange syndrome who have challenging behaviors. It may help reduce self-injury, aggression, and disruptive behavior through a plan families can carry out.
Baltimore, MarylandAges 3–15 - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT05832528Recruiting
Low FODMAP diet for indigestion after meals
This study tests whether a low FODMAP diet can reduce symptoms of functional indigestion or post-meal discomfort. It’s mainly for people whose symptoms are clearly linked to eating and who haven’t changed diets recently.
Leuven, Vlaams-BrabantAges 18–70 - NCT05846802Recruiting
Gastroparesis and stomach symptoms registry for adults
This registry is for adults with long-lasting stomach emptying problems or related symptoms, helping researchers better understand patterns of nausea, pain, and fullness. You may be able to join if you meet specific symptom and test results, and can complete a stomach-emptying scan.
Scottsdale, ArizonaAges 18–85 - NCT05847426Recruiting
Testing early hearing support using brain scans in babies
This study helps improve early hearing care by using a simple brain scan test (fNIRS) in babies with permanent hearing loss. It compares different early intervention approaches and aims to find better ways to support hearing development early on.
East Melbourne, VictoriaAges 24 years+
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.