Clinical trials
Gastric Cancer or Gastroesophageal Junction Adenocarcinoma clinical trials
Below are recruiting gastric cancer or gastroesophageal junction adenocarcinoma clinical trials, each written for real people, not researchers. We’re tracking 1,157 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06727981Recruiting
Immunotherapy as first treatment for stomach cancer
This trial tests immunotherapy as the first treatment for people with advanced or locally advanced stomach cancer. It may help if you haven't had any prior anti-cancer therapy and are starting treatment soon.
Jinan, ShandongAges 18–100 - NCT07724496Recruiting
H. pylori and stomach growth features study
This study looks at whether having H. pylori infection (a common stomach bacteria) and certain features of stomach growth can predict how early stomach cancer or pre-cancerous changes will behave and what your long-term outlook might be. You may be eligible if you are being treated with a camera-based removal procedure called endoscopic submucosal dissection (ESD).
Beijing, Beijing MunicipalityAges 18–80 - NCT03825861RecruitingPhase 2
Before-surgery chemotherapy for locally advanced stomach cancer
This Phase 2 study tests chemotherapy given before surgery (called FOLFIRINOX) for people with locally advanced stomach cancer. The goal is to shrink the tumor and improve outcomes after the surgery plan is completed.
São PauloAges 18–75 - NCT04022109Recruiting
Check gastric cancer using breath chemical signals
This study looks at chemical signals in your breath to help screen for or understand gastric (stomach) cancer. It may help doctors improve earlier detection, or better sort out who may need further tests.
São PauloAges 18 years+ - NCT04740346Recruiting
Study survival and quality of life by follow-up time after stomach surgery
This study looks at how long people with stage II or III stomach (gastric) cancer tend to live and how their day-to-day well-being changes over different follow-up times after surgery. It may help doctors understand the best follow-up schedule to support recovery.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT04843215Recruiting
Surgery comparison for advanced stomach cancer after initial surgery
This trial studies whether removing all of the fatty lining (omentum) or only part of it during surgery leads to better outcomes in people with advanced stomach cancer. It also checks that participants can safely have the same stomach-cancer chemotherapy plan after surgery.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT05698992Recruiting
Rehab program after surgery for esophageal or stomach cancer
This trial tests a rehabilitation and recovery program for people with esophageal or stomach cancer who are planning curative surgery at Skåne University Hospital. It may help you regain strength and function after treatment, using a structured recovery approach.
Lund, LundAges 18 years+ - NCT05991947Recruiting
Blood test for early stomach cancer detection
This study is testing a new way to find stomach (gastric) cancer early using a simple blood test. It may help people who have just been diagnosed with stage I, II, or III stomach cancer and have not started treatment yet.
Hangzhou, ZhejiangAges 18–100 - NCT06102772Recruiting
Combination immunotherapy and targeted therapy for advanced gastric cancer
This trial tests a combination of three drugs—adebrelimab (an immunotherapy), fruquintinib (a targeted therapy to cut off blood supply to the tumor), and a chemotherapy (paclitaxel or albumin-bound paclitaxel)—in people with advanced stomach/gastric cancer whose disease has worsened after one prior chemotherapy. The goal is to see if this new mix can help control the cancer.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06102759Recruiting
Study of adebrelimab and fruquintinib plus chemo for advanced stomach cancer after PD-1 failure
This trial tests a combination of two targeted drugs (adebrelimab and fruquintinib) plus chemotherapy (paclitaxel or albumin-bound paclitaxel) for people with advanced gastric or gastroesophageal junction cancer whose disease progressed after prior PD-1 antibody treatment. The goal is to see if this new combination can help when standard options have stopped working.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06102785Recruiting
Fruquintinib plus TAS102 for advanced stomach cancer
This trial tests a combination of two drugs, fruquintinib and TAS102, for people with advanced stomach cancer that has stopped responding to at least one prior chemotherapy. The goal is to see if this new combination can help shrink tumors or slow the cancer's growth.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06383559RecruitingPhase 2
Combination therapy for advanced AFP-positive gastric cancer
This trial tests a new combination of chemotherapy (XELOX) plus two immunotherapy/targeted drugs (Sintilimab and Lenvatinib) in people with advanced stomach cancer that produces a high level of a protein called AFP. It aims to see if this combination is safe and can shrink tumors when given as the first treatment.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06282809Recruiting
Sound wave therapy for pancreatic cancer
This trial tests a new device that uses sound waves (histotripsy) to break apart pancreatic tumors without surgery. It is for people with advanced pancreatic cancer that cannot be removed and who have already had chemotherapy. The goal is to see if this treatment can help control the tumor.
BarcelonaAges 18 years+ - NCT06487221RecruitingPhase 2
Avutometinib and Defactinib for diffuse stomach cancer
This trial tests two oral drugs, avutometinib and defactinib, for people with a specific type of stomach cancer called diffuse gastric cancer. The goal is to see if these drugs can help shrink or slow the cancer.
New York, New YorkAges 18 years+ - NCT07561073Recruiting
Two surgical approaches for blocked stomachs in advanced gastric cancer
This study compares two different surgical methods to relieve stomach blockage caused by advanced gastric cancer that cannot be removed with standard surgery. The goal is to help patients eat and feel better by restoring food flow through the stomach.
Nanning, GuangxiAges 18–75 - NCT06728878Recruiting
Lymph node spread after total stomach removal for stomach cancer
This study looks at where cancer spreads in the short stomach area after total stomach removal surgery. It aims to understand lymph node and tumor deposits better to help guide future treatment decisions.
Hangzhou, ZhejiangAges 18–85 - NCT06735105Recruiting
Best MRI method for staging stomach cancer
This trial uses three different MRI scanning sequences to see which best helps stage (determine the spread of) stomach cancer. The goal is to improve how doctors plan treatment for gastric cancer.
KunmingAges 18–80 - NCT07067983Recruiting
Gastric cancer screening study with the GRAPE model
This trial is testing a new model called GRAPE to see if it can help find gastric cancer earlier using routine CT scans. If you are between 18 and 80 and having a chest and abdomen CT, you might be able to join.
Hangzhou, ZhejiangAges 18–80 - NCT07142122Recruiting
Comparing two types of stomach surgery for early upper gastric cancer
This trial compares two laparoscopic surgeries for early-stage stomach cancer in the upper part of the stomach. It looks at whether preserving a nerve (celiac branch of vagus nerve) during surgery leads to better recovery while still removing the cancer safely.
Fuzhou, FujianAges 18–75 - NCT07183150Recruiting
Lymph node removal range for advanced stomach cancer
This study is looking at how far surgeons should remove lymph nodes during surgery for advanced stomach cancer. It may help doctors decide the best way to remove cancer while reducing side effects.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07366528RecruitingPhase 3
Comparing two chemo combos for stage III stomach cancer after surgery
This trial compares two chemotherapy combinations (oxaliplatin plus S-1 vs docetaxel plus S-1) for people with stage III stomach cancer who have had complete surgical removal of the tumor. The goal is to see which combination works better to prevent cancer from returning.
Shaoguan, GuandongAges 18–80 - NCT02047994RecruitingPhase 4
Testing and treatment for H. pylori to prevent stomach cancer death
This trial studies whether testing for an infection called H. pylori and using simple blood/screening tests (pepsinogen testing) can help prevent stomach cancer and reduce stomach-cancer-related deaths. You would be followed for health outcomes to see if the approach works better than standard care.
RigaAges 40–64 - NCT07124000Recruiting
T-DXd for advanced HER2-positive solid tumors
This trial is for people with advanced HER2-positive solid tumors (cancers that cannot be removed by surgery or have spread). It tests the drug T-DXd (also called Enhertu) when your doctor has already decided it's the right treatment for you and you have no other good options.
Birmingham, AlabamaAges 18–130 - NCT07059884Recruiting
Exercise program to help people with cancer stay active
This trial tests a distance-based exercise program designed to help people on chemotherapy maintain their physical function and prevent disability. It is for patients with certain cancers who are working full-time and can participate in moderate physical activity.
Dublin, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for gastric cancer or gastroesophageal junction adenocarcinoma?
- Yes. Clin2 currently lists 1,157 recruiting gastric cancer or gastroesophageal junction adenocarcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric cancer or gastroesophageal junction adenocarcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric cancer or gastroesophageal junction adenocarcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Gastric Cancer, Gastroesophageal Junction Cancer
- Gastric / Gastroesophageal Junction Adenocarcinoma
- Gastric or Gastroesophageal Junction Adenocarcinoma
- AFP Gastric or Gastroesophageal Junction Adenocarcinoma
- Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
- Gastroesophageal Junction Adenocarcinoma
- Gastroesophageal-junction Cancer
- Metastatic Gastroesophageal Junction Adenocarcinoma
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.