Clinical trials
Gastric or Gastroesophageal Junction Adenocarcinoma clinical trials
Below are recruiting gastric or gastroesophageal junction adenocarcinoma clinical trials, each written for real people, not researchers. We’re tracking 969 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06341595RecruitingPhase 2
Chemo, radiation and immunotherapy before surgery for stomach cancer with PALM
This trial tests combining chemotherapy, radiation, and an immunotherapy drug (sintilimab) before surgery for advanced stomach cancer that has spread to lymph nodes near the aorta (called PALM). The goal is to see if this approach can shrink the tumor enough to allow complete removal.
Nanjing, JiangsuAges 18–75 - NCT06383559RecruitingPhase 2
Combination therapy for advanced AFP-positive gastric cancer
This trial tests a new combination of chemotherapy (XELOX) plus two immunotherapy/targeted drugs (Sintilimab and Lenvatinib) in people with advanced stomach cancer that produces a high level of a protein called AFP. It aims to see if this combination is safe and can shrink tumors when given as the first treatment.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06395935Recruiting
Wellness care study for gastric cancer survivors
This study tests a wellness program for people who had surgery for gastric cancer (stomach cancer). It aims to help survivors recover better after their operation.
Changwon, Gyeongsandnam-doAges 19–75 - NCT06405113RecruitingPhase 2
Fecal transplant, chemo, and immunotherapy for advanced stomach cancer
This trial tests a combination of fecal microbiota transplant (FMT), chemotherapy (SOX), and an immunotherapy drug (Sintilimab) as a first treatment for advanced stomach or gastroesophageal junction cancer that cannot be removed by surgery. The goal is to see if this combination can shrink tumors and improve outcomes.
ChangzhouAges 18–80 - NCT06420700Recruiting
Stomach Lining Ablation with Sleeve Gastroplasty for Weight Loss
This study combines two endoscopic procedures to help you lose weight: one that reduces the size of your stomach and one that alters the stomach lining. It is designed for people who are ready to commit to long-term diet changes.
Atlanta, GeorgiaAges 18–65 - NCT06451211RecruitingPhase 2
Immuno-chemo before surgery for thick or large stomach cancers
This trial tests a combination of immunotherapy and chemotherapy given before surgery to shrink stomach cancers that are particularly thick or large. It aims to see if this approach can make these hard-to-treat tumors easier to remove and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT06451393Recruiting
AI predicts stomach cancer response to chemo
This trial tests a computer-based model that uses CT scans, endoscopic images, and biopsy tissue to predict how well stomach cancer will respond to chemotherapy given before surgery. The goal is to help doctors choose the best treatment for each patient.
Guangzhou, GuangdongAges 20–90 - NCT06472063Recruiting
Surgery first vs chemo then surgery for advanced stomach cancer
This trial compares two approaches for stomach cancer that has spread a bit but can still be removed with surgery. One group has surgery first, the other gets chemotherapy before surgery. The goal is to see which sequence leads to better long-term outcomes.
Orbassano, PiedmontAges 18 years+ - NCT06475417RecruitingPhase 2
Adebrelimab plus chemo before stomach cancer surgery
This trial tests a combination of chemotherapy (DOS) plus an immunotherapy drug (Adebrelimab) given before surgery for people with locally advanced stomach or gastroesophageal junction cancer. The goal is to see if the treatment shrinks the tumor and improves outcomes.
Xi'an, ShannxiAges 18–75 - NCT06485271Recruiting
Camrelizumab for advanced gastric cancer
This trial tests a drug called camrelizumab, alone or with other treatments, for people with advanced stomach cancer that has worsened or returned. It aims to see how well this treatment works in real-world patients.
Changzhi, ShanxiAges 18–75 - NCT07441850Recruiting
Digital rehab for stomach cancer patients after chemo or radiation
This trial is testing a smartphone-based exercise and recovery program for people with stomach cancer who have had chemo or radiation before surgery. It aims to help you get back on your feet faster after surgery.
BeijingAges 18–70 - NCT06487429RecruitingPhase 2
Short radiation followed by combo therapy for HER2+ stomach cancer
This trial tests a new approach for stomach cancer that has spread to nearby tissues but not to other organs. You would get a short course of radiation, followed by a combination of targeted therapy (Disitamab Vedotin), chemotherapy (S-1), and immunotherapy (Sintilimab) before surgery to shrink the tumor and improve outcomes.
Wuhan, HubeiAges 18–75 - NCT06487221RecruitingPhase 2
Avutometinib and Defactinib for diffuse stomach cancer
This trial tests two oral drugs, avutometinib and defactinib, for people with a specific type of stomach cancer called diffuse gastric cancer. The goal is to see if these drugs can help shrink or slow the cancer.
New York, New YorkAges 18 years+ - NCT06493032Recruiting
Gastric mapping to check G-POEM success
This study uses a non-invasive stomach-mapping test (BSGM) to see if a G-POEM procedure (a treatment for gastroparesis) works well. It may help doctors better understand how the stomach empties after the procedure.
Indianapolis, IndianaAges 18 years+ - NCT06495645Recruiting
Computer-aided endoscopy to find stomach growths
This trial tests a computer-aided system used during upper endoscopy to find stomach growths that might be missed. It may help improve detection of early stomach cancer or precancerous changes.
Hong KongAges 40 years+ - NCT06555471RecruitingPhase 2
Sintilimab plus chemo-radiation for older adults with advanced stomach cancer
This trial tests whether adding the immunotherapy drug sintilimab to standard chemoradiotherapy can help people aged 75 or older with locally advanced stomach cancer. It aims to shrink tumors and improve outcomes.
Nanjing, JiangsuAges 75 years+ - NCT06564246RecruitingPhase 4
Comparing Vonoprazan vs. Pantoprazole for GERD
This trial tests a newer medication called vonoprazan against the standard treatment pantoprazole for patients with gastroesophageal reflux disease (GERD). The goal is to see which one works better for controlling symptoms like heartburn and acid reflux over 8 weeks.
GizaAges 17–60 - NCT06580574RecruitingPhase 2
Immunotherapy to save the stomach or colon from surgery
This trial tests whether using immune checkpoint inhibitors alone (like checkpoint blockade drugs) can help people with certain gastric or colon cancers avoid surgery. It's for patients whose tumors have a specific genetic feature called dMMR/MSI-H and haven't spread to other parts of the body.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06582576Recruiting
How gastric electrical stimulation helps gastroparesis
This study looks at how a gastric electrical stimulator works to treat gastroparesis. It compares people who feel their symptoms improve a lot or not much, to understand the device's effects.
Aarhus NAges 18 years+ - NCT06597526Recruiting
PET/CT scanning to guide treatment for stomach cancer with abdominal spread
This trial uses two types of PET/CT scans (FDG and FAPI) to see how well chemotherapy or other treatments work before surgery for stomach cancer that has spread to the lining of the abdomen. The goal is to find the best way to measure treatment response and help guide your care.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06608381RecruitingPhase 3
Comparing partial vs. total omentectomy in gastric cancer surgery
This trial compares removing part or all of the fatty lining of the stomach (omentum) during minimally invasive surgery for a certain stage of gastric cancer. The goal is to see if removing less tissue is as safe and effective.
SeoulAges 20–85 - NCT06613438Recruiting
New wearable device for GERD symptoms
This study tests a new wearable device (eGERD) that aims to reduce symptoms of GERD (heartburn and regurgitation). The trial will check if the device is safe and works well without needing medication.
Chicago, IllinoisAges 22–75 - NCT06639490Recruiting
Robot-assisted stomach surgery navigation study
This trial tests a special navigation system to help surgeons perform robot-assisted stomach cancer surgery. It aims to make the surgery more precise and safe.
SeoulAges 20–90 - NCT06661668Recruiting
Stomach pacemaker implant for severe gastroparesis
This study tests whether placing a small, implanted device that sends gentle electrical pulses to the stomach can improve symptoms of severe gastroparesis—a condition where the stomach empties too slowly. It's for people whose symptoms haven't been controlled with other treatments and are significantly affecting their daily life.
Cologne, North Rhine-WestphaliaAges 18 years+
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Common questions
- Are there clinical trials for gastric or gastroesophageal junction adenocarcinoma?
- Yes. Clin2 currently lists 969 recruiting gastric or gastroesophageal junction adenocarcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric or gastroesophageal junction adenocarcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric or gastroesophageal junction adenocarcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Gastric / Gastroesophageal Junction Adenocarcinoma
- AFP Gastric or Gastroesophageal Junction Adenocarcinoma
- Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
- Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
- Gastroesophageal Junction Adenocarcinoma
- Metastatic Gastroesophageal Junction Adenocarcinoma
- Gastroesophageal Junction (GEJ) Adenocarcinoma
- Advanced Gastroesophageal Junction Adenocarcinoma
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.