Clinical trials
Gastric clinical trials
Below are recruiting gastric clinical trials, each written for real people, not researchers. We’re tracking 850 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06826079RecruitingPhase 2
Sorbitol plus chemo and immunotherapy for advanced gastric cancer
This trial tests adding sorbitol to standard chemotherapy and an immunotherapy drug (tirellizumab) for people with locally advanced stomach cancer. The goal is to see if this combination is safe and helps shrink tumors before surgery.
Wuhan, HubeiAges 18–70 - NCT06789172RecruitingPhase 1
New drug OKN4395 with or without pembrolizumab for solid tumors
This trial tests a new oral drug called OKN4395, which targets a COX2-related immune pathway, alone or with the immunotherapy pembrolizumab, in people with advanced solid tumors. It may be an option if you have certain types of cancer that have stopped responding to other treatments.
Beverly Hills, CaliforniaAges 18 years+ - NCT06768463Recruiting
Stomach cancer surgery after chemo for limited spread
This trial tests if surgery to remove the stomach and some tumors, after a few months of chemo, helps people whose stomach cancer has spread to only a few nearby spots (like the lining of the belly, liver, or lymph nodes) live longer compared to chemo alone.
Ho Chi Minh City, Ho Chi MinhAges 18–75 - NCT06728878Recruiting
Lymph node spread after total stomach removal for stomach cancer
This study looks at where cancer spreads in the short stomach area after total stomach removal surgery. It aims to understand lymph node and tumor deposits better to help guide future treatment decisions.
Hangzhou, ZhejiangAges 18–85 - NCT06532006RecruitingPhase 3
HLX22 plus trastuzumab and chemo for HER2+ stomach cancer
This trial tests adding a new drug, HLX22, to the standard combination of trastuzumab and chemotherapy for people with HER2-positive stomach or gastroesophageal junction cancer that hasn't been treated yet. The goal is to see if this three-drug mix works better than the usual two-drug approach.
Anaheim, CaliforniaAges 18 years+ - NCT05640947Recruiting
Procedure to reverse bypass using an endoscopic stent
This trial studies a minimally invasive procedure that uses a stent placed through an endoscope to create a new connection in the stomach, with the goal of reversing a Roux-en-y gastric bypass. It may help people whose bypass has led to nutrition problems, severe dumping symptoms, difficult marginal ulcers, or liver scarring that worsens after surgery.
BrugesAges 18 years+ - NCT06038578RecruitingPhase 2
TRK-950 with standard chemo for advanced stomach cancer
This trial tests a new drug, TRK-950, added to standard chemotherapy (ramucirumab and paclitaxel) for people with advanced stomach or gastroesophageal junction cancer that has worsened after previous treatment. The goal is to see if this combination can help shrink tumors or slow disease progression.
Duarte, CaliforniaAges 18 years+ - NCT05725967Enrolling by invitation
Endoscopic and bariatric procedures for obesity
This study looks at people who are having obesity-related procedures, including options done with a scope (endoscopic) and revision after prior bariatric surgery. It may help doctors understand outcomes and improve care for people undergoing these treatments.
Boston, MassachusettsAges 18–80 - NCT05514769Recruiting
Surgery type comparison for early-to-mid stomach cancer
This trial compares two different stomach cancer surgeries after removing the tumor, to see which works better for patients with stomach adenocarcinoma. It may help determine the safest approach and best recovery outcomes for people whose cancer has not spread.
Nanchong, SichuanAges 18–85 - NCT04191551Recruiting
Study of stomach precancer conditions during endoscopy
This study looks at people with certain stomach symptoms or precancer risk factors when they get a camera test of the upper digestive tract (endoscopy). The goal is to learn how to better detect and evaluate stomach precancer conditions early, which may help guide treatment or follow-up.
Stanford, CaliforniaAges 35–84 - NCT05320796RecruitingPhase 4
Esomeprazole study after gastric bypass and pouch acid levels
This trial tests how well esomeprazole (a acid-reducing medicine) works after a Roux-en-Y gastric bypass, and how it changes the acidity in the stomach pouch. It may help confirm the best way to control stomach acid after bypass surgery.
Schlieren, SchlierenAges 18 years+ - NCT03821636Recruiting
Compare gastric bypass limb lengths for type 2 diabetes remission
This study looks at whether a gastric bypass surgery with a longer intestine segment or a longer bile drainage segment leads to better type 2 diabetes remission in people with severe obesity. It may help doctors choose the most effective surgical approach and follow-up plan for diabetes improvement.
AmiensAges 18–60 - NCT04894838Recruiting
Testing a bypass revision surgery for weight regain
This study looks at whether a specific stomach bypass revision (a “distal gastric bypass”) can improve outcomes after Roux-en-Y gastric bypass when weight loss was not enough or weight was regained. You may be considered if you meet weight-loss goals criteria and can join follow-up and possibly surgery.
Arnhem, GelderlandAges 18–65 - NCT03900910Recruiting
Gastric cancer prevention program for Indigenous adults
This trial studies a prevention approach to help lower the chance of stomach (gastric) cancer in Indigenous people. You may be able to join if you’re in the right age range, can understand consent, and are not pregnant or dealing with serious other illnesses.
Taipei, TaiwanAges 20–60 - NCT03161522RecruitingPhase 2
Chemo alone versus with radiation or surgery for limited spread
This study tests whether adding radiation or surgery to chemotherapy can improve outcomes for people whose esophageal or stomach cancer has spread to only a few places. If your cancer is “oligometastatic” (up to 3 spots), the trial helps doctors see which approach gives the best control.
Houston, TexasAges 18–79 - NCT02665923Recruiting
Testing stomach emptying after formula in babies
This study measures how quickly a baby’s stomach empties after formula feeding. It may help doctors better understand normal digestion timing in newborns and infants.
New York, New YorkAges Up to 1 year - NCT01514045Recruiting
Gastric cancer registry for patients and certain family members
This study builds a registry (a secure database) to learn about people with gastric cancer, people at higher risk because of family history, and people with a specific inherited gene change. Being in the registry may help researchers understand causes and improve future care.
Stanford, CaliforniaAges 18 years+ - NCT06764875RecruitingPhase 3
New drug combo for HER2-positive stomach cancer
This trial tests a new immunotherapy called rilvegostomig combined with standard chemotherapy and a targeted therapy (trastuzumab deruxtecan) for people with advanced HER2-positive stomach or gastroesophageal junction cancer that has not been treated before.
Anchorage, AlaskaAges 18 years+ - NCT07431281RecruitingPhase 3
New drug combo for advanced stomach cancer with CLDN18.2
This trial tests a new drug combination for people with advanced stomach cancer that has not been treated before. It looks at two groups: one with PD-L1 (a protein that helps decide if immunotherapy works), and one without. The treatment includes an antibody-drug conjugate (Sonesitatug Vedotin) plus standard chemotherapy, with or without an immunotherapy drug.
Birmingham, AlabamaAges 18 years+ - NCT07554521RecruitingPhase 2
Tislelizumab Plus Chemotherapy for Advanced Stomach or Esophageal Cancer
This study tests a combination of two drugs—tislelizumab (an immunotherapy) and chemotherapy—to treat advanced stomach, gastroesophageal junction, or esophageal cancer that cannot be surgically removed. The trial focuses on recruiting patients from racial and ethnic minority communities to ensure the treatment is studied in diverse populations.
Bullhead City, ArizonaAges 18 years+ - NCT02811900Recruiting
Study of outcomes after weight-loss (bariatric) surgery
This study follows adults who have bariatric (weight-loss) surgery to see what outcomes they experience afterward. It may help doctors better understand how well the surgery works in real life.
StrasbourgAges 18 years+ - NCT01344525Recruiting
Study of team-based therapy for obesity and weight loss
This study looks at an interdisciplinary, team-based obesity treatment plan and how well it helps people lose significant weight over time. You might be a candidate if you are an adult with obesity who already achieved more than 10% weight loss within about 6 months from a lifestyle program or weight-loss surgery.
HeidelbergAges 18–65 - NCT03385018Recruiting
Laparoscopic total stomach surgery trial for stomach cancer
This trial studies whether a minimally invasive (laparoscopic) removal of the entire stomach, along with lymph node removal, can be done safely and effectively for certain stomach cancers. It may be an option if your cancer is in the stomach, has limited spread to nearby lymph nodes, and can be fully removed.
SeoulAges 20–80 - NCT03961373RecruitingPhase 3
Standard vs longer lymph node surgery after chemo for stomach cancer
This study compares two surgical approaches to remove lymph nodes after you’ve already had chemotherapy for stomach cancer. It aims to see whether removing lymph nodes in a more extended way improves outcomes without causing unacceptable side effects.
SienaAges 18–80
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Common questions
- Are there clinical trials for gastric?
- Yes. Clin2 currently lists 850 recruiting gastric studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.