Clinical trials · Massachusetts
Gastrointestinal Diseases clinical trials in Massachusetts
We’re tracking 15 recruiting gastrointestinal diseases studies with a site in Massachusetts — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT07222800RecruitingPhase 3
Testing a new drug plus chemo for stage 4 colorectal cancer
This study tests a new experimental drug (PF-08634404) combined with standard chemotherapy for people with stage 4 colorectal cancer who have not yet been treated for their advanced disease. The goal is to see if the combination helps shrink or slow the growth of tumors.
Boston, MassachusettsAges 18 years+ - NCT05209568Recruiting
Study of immune reactions after eating gluten
This study looks at how your immune system responds when you eat gluten, including for people with celiac disease. You may be asked to follow a gluten-free diet first and then safely reintroduce gluten so researchers can measure immune changes.
Boston, MassachusettsAges 2–101 - NCT07351071Recruiting
Study of Signia circular stapler in left colon and rectal surgery
This study is testing a new circular stapler, called the Signia, used to reconnect the bowel during planned left-sided colon or rectal surgery. It aims to see how well the device works in everyday hospital settings.
Boston, MassachusettsAges 18 years+ - NCT04565704Enrolling by invitation
Imaging checks on biopsy samples during routine scopes
This study uses special optical imaging during routine upper or lower endoscopy to look at biopsy tissue and compare what the images show with standard lab microscope results. It may help improve how doctors spot abnormal tissue during procedures.
Boston, MassachusettsAges 18 years+ - NCT04924075RecruitingPhase 2
Belzutifan for cancers linked to VHL or HIF-2α changes
This Phase 2 study tests belzutifan (MK-6482) to treat certain advanced cancers caused by specific gene or disease changes, including VHL-related tumors and HIF-2α related tumors. It may help shrink tumors or slow their growth in people whose cancer matches these genetic or disease patterns.
Boston, MassachusettsAges 12 years+ - NCT03369353Enrolling by invitation
Personalized immune testing study for bowel and transplant patients
This study looks at whether a precise lab test can help understand inflammatory bowel disease, functional gut disorders, and immune changes after stem cell transplant or cell therapy. It may help doctors choose better monitoring and treatments based on your immune and gut test results.
Boston, MassachusettsAges Any age - NCT05443321Enrolling by invitation
Health information sharing during hospital transfers
This trial studies whether sharing patients’ health information between hospitals during transfers can improve outcomes. You may be included if you are moved from a specific partner hospital to Brigham and Women’s Hospital and admitted to certain hospital units.
Boston, MassachusettsAges 18 years+ - NCT03848962Recruiting
Share leftover or collected samples for research
This study helps collect and share human samples (like blood or other specimens) so researchers can do new studies. It’s mainly about providing samples for research use, not testing a treatment on you.
Lexington, MassachusettsAges 1 month–89 years - NCT06529159Recruiting
Treating H. pylori with argon plasma during endoscopy
This trial tests a new way to treat H. pylori infection using argon plasma (a kind of energy) during an upper endoscopy. It may help people who haven't yet taken antibiotics for H. pylori and are already having an endoscopy.
Boston, MassachusettsAges 18 years+ - NCT06200961Recruiting
Trans-nasal endoscopy for bariatric patients
This study tests a thinner, more comfortable endoscope that goes through the nose instead of the mouth for patients who need an upper GI exam. It may be a gentler option for weight-loss surgery patients.
Boston, MassachusettsAges 18–90 - NCT07033208Recruiting
Testing a wireless thermal capsule for the digestive tract
This study tests a new wireless capsule that you swallow, like a pill, to measure temperature inside your digestive tract. It is for healthy volunteers to see if the device is safe and works well.
Boston, MassachusettsAges 18–75 - NCT05295446Enrolling by invitation
GI symptom registry for adults with functional bowel issues
This study is a registry (a way to collect health information) for adults with certain long-term “functional” gastrointestinal (GI) problems. It may help doctors better understand these conditions and improve future treatments.
Boston, MassachusettsAges 18 years+ - NCT04566341Enrolling by invitation
Study gut problems in Parkinson’s and changes in gut nerves
This study looks at how digestive (gut) problems happen in people with Parkinson’s and whether there are related changes in the nerve tissue in the digestive tract. It may help researchers better understand the cause of these symptoms and find new ways to monitor or treat them.
Boston, MassachusettsAges 40–85 - NCT07219537Recruiting
Imaging the lower gut with a new capsule
This trial tests a new type of camera capsule that takes pictures of the lower part of your digestive tract. It may be an option for people who are healthy or have Lynch Syndrome and have had a recent normal colonoscopy.
Boston, MassachusettsAges 18–75 - NCT05978141Recruiting
T-cell lymphoma registry study
This study creates a registry for people with certain T-cell or NK-cell lymphomas. It collects health information and tumor samples to learn more about these diseases and improve future treatments.
Boston, MassachusettsAges Any age
Gastrointestinal Diseases trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting gastrointestinal diseases studies listed above.
- Massachusetts General Hospital · 9 studies
- Brigham and Women's Hospital · 4 studies
- Dana-Farber Cancer Institute · 3 studies
- Boston Children's Hospital · 2 studies
- Dana-Farber Cancer Institute at Foxborough
- Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Medical Center
- iSpecimen
What taking part in a gastrointestinal diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Gastrointestinal Diseases trials in other states
Common questions
- Are there gastrointestinal diseases clinical trials in Massachusetts?
- Yes. We're currently tracking 15 recruiting gastrointestinal diseases studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a gastrointestinal diseases study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a gastrointestinal diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New gastrointestinal diseases studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.