Clinical trials
Gastrointestinal Diseases clinical trials
Below are recruiting gastrointestinal diseases clinical trials, each written for real people, not researchers. We’re tracking 86 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07222800RecruitingPhase 3
Testing a new drug plus chemo for stage 4 colorectal cancer
This study tests a new experimental drug (PF-08634404) combined with standard chemotherapy for people with stage 4 colorectal cancer who have not yet been treated for their advanced disease. The goal is to see if the combination helps shrink or slow the growth of tumors.
Chandler, ArizonaAges 18 years+ - NCT05041374Recruiting
Study for adults with digestive or liver problems
This study looks at adults who have known or possible problems in the digestive system or liver. It may help patients by offering structured evaluation and follow-up for their condition.
Bethesda, MarylandAges 18–120 - NCT05252078RecruitingPhase 2
Anlotinib plus an injection after esophageal cancer surgery
This Phase 2 study tests whether anlotinib tablets combined with an injection (TQB2450) can lower the risk of esophageal squamous cell cancer coming back after surgery. It may help by targeting cancer growth signals and blood-vessel formation to reduce recurrence.
Nanchang, JiangxiAges 18 years+ - NCT05115877Enrolling by invitation
Looking back at treatment outcomes for stomach or gut diseases
This study looks at past care for adults who had non-cancer or cancer of the gastrointestinal (stomach and intestines) tract and compares treatment outcomes. It may help improve how doctors manage these conditions in the future.
Richardson, TexasAges 18 years+ - NCT04949282Recruiting
Lutetium-177 treatment for advanced somatostatin-positive tumors
This study looks at outcomes for adults with tumors that are advanced (can’t be fully removed or has spread) and are getting worse, where tests show somatostatin receptors. It aims to understand how treatment with lutetium-177 helps people in this situation.
Santiago de Compostela, A CoruñaAges 18–100 - NCT05209568Recruiting
Study of immune reactions after eating gluten
This study looks at how your immune system responds when you eat gluten, including for people with celiac disease. You may be asked to follow a gluten-free diet first and then safely reintroduce gluten so researchers can measure immune changes.
Aurora, ColoradoAges 2–101 - NCT07351071Recruiting
Study of Signia circular stapler in left colon and rectal surgery
This study is testing a new circular stapler, called the Signia, used to reconnect the bowel during planned left-sided colon or rectal surgery. It aims to see how well the device works in everyday hospital settings.
New Haven, ConnecticutAges 18 years+ - NCT06227468Recruiting
Mapping immune system genes in Greek adults
This study maps immune system genes (HLA) in Greek adults. It uses a simple cheek swab sample to collect data, with no experimental treatment.
Chaïdári, AtticaAges 18 years+ - NCT06340620Recruiting
Comparing a new ultrasound tool to the standard scope
This study compares a new, possibly easier-to-use ultrasound tool (EndoSound Vision System) to the standard echoendoscope for looking at organs like the pancreas, bile duct, or lymph nodes. If you are already scheduled for an endoscopic ultrasound, you may be able to join.
Orlando, FloridaAges 18–100 - NCT06271538RecruitingPhase 4
Skal Pro Powder for IBS symptoms
This study tests if Skal Pro Powder, a probiotic, can help relieve symptoms of Irritable Bowel Syndrome (IBS). It is for adults with any type of IBS who haven't used certain other treatments recently.
Kubang Kerian, KelantanAges 18 years+ - NCT04565704Enrolling by invitation
Imaging checks on biopsy samples during routine scopes
This study uses special optical imaging during routine upper or lower endoscopy to look at biopsy tissue and compare what the images show with standard lab microscope results. It may help improve how doctors spot abnormal tissue during procedures.
Boston, MassachusettsAges 18 years+ - NCT05782010Recruiting
Testing a hemorrhoid device for grade II or III hemorrhoids
This study tests how safe and well a hemorrhoid treatment device (PexyEazy®) works for adults with moderate-to-severe hemorrhoids (grade II–III). You may be a candidate if you fit the hemorrhoid grade and medical safety requirements and can follow the study plan.
FrölundaAges 18–84 - NCT06868875Recruiting
Small bowel MRI data sharing study
This study asks permission to use past MRI scans of your small bowel for research. It aims to improve how we understand and diagnose bowel conditions.
LondonAges 16 years+ - NCT06940596Recruiting
Comparing diets and therapies for irritable bowel syndrome
This study compares different dietary and behavioral treatments to find out which works best for different people with irritable bowel syndrome (IBS). You'll be asked to follow a specific treatment program to see how it affects your symptoms.
Melbourne, VictoriaAges 18 years+ - NCT03319446Enrolling by invitation
Sharing anonymous samples for a diagnostic test
This trial collects and stores anonymous samples from consenting adults. It helps researchers evaluate or improve diagnostic testing without using your personal identity.
Salt Lake City, UtahAges 18–99 - NCT05494060RecruitingPhase 2
Adjuvant chemo plus immunotherapy for ctDNA-positive stomach cancer
This trial tests whether adding an anti-cancer immune treatment and another targeted drug to standard chemotherapy after surgery can lower the chance of cancer coming back. It is for people whose blood test (ctDNA) shows leftover cancer-related DNA after surgery.
Nanjing, JiangsuAges 18–75 - NCT07687706RecruitingPhase 3
Tegoprazan to prevent stomach problems after stroke
This study tests a stomach-protecting medicine called tegoprazan for people who have had a stroke and are starting antiplatelet therapy. It aims to prevent stomach complications like ulcers or bleeding.
Busan, BusanAges 19 years+ - NCT05274854Recruiting
Practice change study for severe unexplained gut symptoms
This study looks at a new approach to care for adults with severe, long-lasting stomach or bowel symptoms when no clear cause has been found. It may help you get more coordinated support through an integrated care clinic.
Woolloongabba, QueenslandAges 18–90 - NCT06679478Enrolling by invitation
Early walking after stomach or bowel surgery
This study tests whether a structured early walking plan helps people recover faster after open gastrointestinal surgery. You will use a phone app to track your steps.
KütahyaAges 18–80 - NCT06604728Recruiting
IV vs. shot biologics for IBD: which works better?
This study compares intravenous (IV) and under-the-skin (subcutaneous) biologic drugs for people with Crohn's disease or ulcerative colitis. It helps doctors understand if switching from the IV form to a shot is as effective and well-tolerated.
RomaAges 18 years+ - NCT06877923Recruiting
Elemental 028 extra nutritional support study
This study is testing a special liquid food called Elemental 028 Extra for people who need at least 30% of their nutrition from an elemental formula. It aims to see how well it works and how people tolerate it.
TrowbridgeAges 3 years+ - NCT00267501Recruiting
Study collects data and samples to understand eosinophilic conditions
This study collects information and biological samples to better understand what causes certain allergic/eosinophilic conditions. It may help researchers learn mechanisms and improve future care.
Cincinnati, OhioAges Any age - NCT04924075RecruitingPhase 2
Belzutifan for cancers linked to VHL or HIF-2α changes
This Phase 2 study tests belzutifan (MK-6482) to treat certain advanced cancers caused by specific gene or disease changes, including VHL-related tumors and HIF-2α related tumors. It may help shrink tumors or slow their growth in people whose cancer matches these genetic or disease patterns.
Los Angeles, CaliforniaAges 12 years+ - NCT03369353Enrolling by invitation
Personalized immune testing study for bowel and transplant patients
This study looks at whether a precise lab test can help understand inflammatory bowel disease, functional gut disorders, and immune changes after stem cell transplant or cell therapy. It may help doctors choose better monitoring and treatments based on your immune and gut test results.
Boston, MassachusettsAges Any age
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Gastrointestinal Diseases trials by city
Studies with a site in or near these metro areas.
Gastrointestinal Diseases trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for gastrointestinal diseases?
- Yes. Clin2 currently lists 86 recruiting gastrointestinal diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.