Clinical trials
Gender clinical trials
Below are recruiting gender clinical trials, each written for real people, not researchers. We’re tracking 102 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06953908Recruiting
The Copenhagen Gender Identity Study
This trial follows all patients referred to the Center for Gender Identity in Copenhagen to learn more about their experiences and needs. If you are referred there and can read Danish, you may join.
CopenhagenAges 18 years+ - NCT05587751Recruiting
Testing how gender-affirming care affects lung function
This study checks whether gender-affirming treatments change breathing/lung test results over time. It may help doctors understand any lung-related effects for transgender and gender-diverse people.
Rochester, MinnesotaAges 14 years+ - NCT06573177Recruiting
Better care for young people with gender identity questions
This trial is designed to improve how healthcare is provided to young people who are exploring their gender identity. If you have already been accepted into a gender identity service, you may be able to join and help shape better care for others.
Copenhagen, Capital RegionAges Up to 18 years - NCT06565663Enrolling by invitation
Decision aid for gender-affirming surgeries
This study tests an online decision tool for people considering metoidioplasty or phalloplasty. The tool helps patients compare surgical options to make informed choices.
Hanover, New HampshireAges 18 years+ - NCT06291675Recruiting
Hormone therapy's effect on heart and organ fat
This study uses MRI scans to see how gender-affirming hormone therapy affects heart muscle, heart function, and fat in the heart, liver, and pancreas. It may help us understand long-term health effects of hormone therapy.
Vienna, State of ViennaAges 18 years+ - NCT05649605Recruiting
Testing early response to gender-affirming hormone treatment
This study looks at how people respond early after starting gender-confirming hormones. It may help doctors understand what changes happen soon after treatment starts and how to manage it safely.
StockholmAges 18–99 - NCT07726290Recruiting
Testing AI to predict gender from jawbone scans
This trial uses 3D jaw scans to see if an AI can accurately predict a person's gender. It might help if you have a clear scan of your jaw.
CairoAges 18 years+ - NCT07474363Recruiting
Depression differences between men and women
This study looks at how depression affects men and women differently, including symptoms, strength to cope (resilience), and feelings of stigma. It aims to understand these differences to improve treatment.
Eskişehir, EskişehirAges 18–65 - NCT07402265Recruiting
Online support for suicidal thoughts in LGBTQ+ youth
This trial tests a brief online program for teens and young adults who identify as sexual or gender minorities and have had suicidal thoughts in the last 6 months. It aims to see if this virtual help can reduce those thoughts and make participants feel better.
London, OntarioAges 13–25 - NCT07324967Recruiting
Counseling for transmasculine patients before gender-affirming surgery
This study tests a counseling approach to help transmasculine and non-binary people prepare for a hysterectomy (removal of the uterus) as part of gender-affirming care. The goal is to see if this counseling improves knowledge and decision-making.
Minneapolis, MinnesotaAges 18–65 - NCT06362837Recruiting
Nutrition, hygiene, and sexual health program for families
This trial tests a program called REACTS-IN to improve nutrition, hygiene, and sexual/reproductive health. It is designed for mothers, fathers, adolescents, and young children living in communities in Kenya.
DhakaAges Any age - NCT07286123Recruiting
Vaginoplasty using fish skin graft for transgender women
This trial tests a new surgical technique for gender-affirming vaginoplasty that uses a fish skin graft (Kerecis) to create the vaginal lining. It may be an option for transgender women planning this type of surgery for the first time.
Cleveland, OhioAges 19–99 - NCT07252687Recruiting
How Gender-Affirming Care Affects Breast Perception in Trans Men
This study looks at how gender-affirming treatments (like hormone therapy or chest surgery) affect how trans men feel about their chest. It aims to help understand the best timing for these treatments.
InnsbruckAges 16 years+ - NCT07187947Recruiting
Heart health in transgender people on hormone therapy
This study looks at how gender-affirming hormone therapy affects the heart and blood vessels in transgender people. If you've been on hormones for at least a year, researchers want to check your cardiovascular health to better understand long-term risks and benefits.
Bologna, BOAges 18 years+ - NCT07131267Recruiting
Study on sexual health in trans men during transition
This study aims to understand how sexual function changes for trans men as they go through the gender affirmation process. The results could help doctors provide better support for your sexual health during your transition.
Eskişehir, TürkiyeAges 18–65 - NCT07128771Enrolling by invitation
Heart effects of gender-affirming hormone therapy
This study looks at how gender-affirming hormone therapy affects the heart and blood vessels. It aims to understand any changes in heart health for transgender individuals starting or continuing this treatment.
Oslo, OsloAges 16 years+ - NCT07075731Recruiting
Cervical and endometrial cancer screening before gender-affirming hysterectomy
This study looks at how to best screen for cervical and endometrial (uterine lining) cancer in transgender and gender-diverse people who have had or plan to have a hysterectomy (surgery to remove the uterus and cervix). It aims to make screening more comfortable and effective for this community.
Minneota, MinnesotaAges 18 years+ - NCT06774053Recruiting
The SPECTRA study for transgender and gender diverse people
This study follows transgender and gender diverse people of all ages 16 and older to learn more about their health and well-being over time. It is for those who have a diagnosis of gender incongruence and are either starting, continuing, or have stopped gender affirming therapy.
BaselAges 16 years+ - NCT06777849Recruiting
Life skills program to reduce violence against girls in Pakistan
This study tests a life skills and play-based program in schools to reduce violence against girls. It aims to make schools safer and help girls stay in school.
Karachi, SindhAges 10–16 - NCT06747052Recruiting
How gender affects physical activity for preventing joint pain
This study looks at how being male or female affects physical activity habits and how that might help prevent long-term muscle and joint problems. It is open to adults in Lombardy, Italy, who can speak Italian.
Milan, ItalyAges 18–64 - NCT06670053Recruiting
Testosterone and brain development in teens
This study looks at how starting testosterone therapy affects brain development in transgender and gender-diverse youth. It may help you and your doctor understand the changes to expect.
Aurora, ColoradoAges 12–20 - NCT06489899Recruiting
Peer education for substance use and gender fairness in teens
This trial tests a program where young people learn from peers about reducing substance use and promoting gender equity. Participants will join workshop sessions and vocational training to build skills and healthier habits.
Cape Town, Western CapeAges 16–24 - NCT06443164Enrolling by invitation
Chronic Pain Treatment Before Gender-Affirming Surgery
This study tests a one-session pain management class called Empowered Relief for people with chronic pain who are planning gender-affirming surgery. The goal is to see if learning these skills before surgery helps with pain afterward.
Portland, OregonAges 18–100 - NCT06441942Recruiting
Women with heart attack or unstable angina study
This study is a registry that collects information about women who have had a heart attack or unstable angina. The goal is to learn more about how these conditions affect women and improve care for women with heart disease.
Milan, Italy MilanAges 18–100
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Common questions
- Are there clinical trials for gender?
- Yes. Clin2 currently lists 102 recruiting gender studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gender trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gender trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.