Clinical trials
Gender clinical trials
Below are recruiting gender clinical trials, each written for real people, not researchers. We’re tracking 105 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06362837Recruiting
Nutrition, hygiene, and sexual health program for families
This trial tests a program called REACTS-IN to improve nutrition, hygiene, and sexual/reproductive health. It is designed for mothers, fathers, adolescents, and young children living in communities in Kenya.
DhakaAges Any age - NCT06441942Recruiting
Women with heart attack or unstable angina study
This study is a registry that collects information about women who have had a heart attack or unstable angina. The goal is to learn more about how these conditions affect women and improve care for women with heart disease.
Milan, Italy MilanAges 18–100 - NCT06489899Recruiting
Peer education for substance use and gender fairness in teens
This trial tests a program where young people learn from peers about reducing substance use and promoting gender equity. Participants will join workshop sessions and vocational training to build skills and healthier habits.
Cape Town, Western CapeAges 16–24 - NCT06670053Recruiting
Testosterone and brain development in teens
This study looks at how starting testosterone therapy affects brain development in transgender and gender-diverse youth. It may help you and your doctor understand the changes to expect.
Aurora, ColoradoAges 12–20 - NCT06747052Recruiting
How gender affects physical activity for preventing joint pain
This study looks at how being male or female affects physical activity habits and how that might help prevent long-term muscle and joint problems. It is open to adults in Lombardy, Italy, who can speak Italian.
Milan, ItalyAges 18–64 - NCT07131267Recruiting
Study on sexual health in trans men during transition
This study aims to understand how sexual function changes for trans men as they go through the gender affirmation process. The results could help doctors provide better support for your sexual health during your transition.
Eskişehir, TürkiyeAges 18–65 - NCT07147166Recruiting
Testing a device to prevent raised scars after top surgery
This study tests a special bandage-like device (Brijjit) that may help reduce thick, raised scars after gender-affirming mastectomy (top surgery). If you are having double incision top surgery and want to see if this device can give you flatter, less noticeable scars, this trial may be a good fit.
San Francisco, CaliforniaAges 19 years+ - NCT07187947Recruiting
Heart health in transgender people on hormone therapy
This study looks at how gender-affirming hormone therapy affects the heart and blood vessels in transgender people. If you've been on hormones for at least a year, researchers want to check your cardiovascular health to better understand long-term risks and benefits.
Bologna, BOAges 18 years+ - NCT07252687Recruiting
How Gender-Affirming Care Affects Breast Perception in Trans Men
This study looks at how gender-affirming treatments (like hormone therapy or chest surgery) affect how trans men feel about their chest. It aims to help understand the best timing for these treatments.
InnsbruckAges 16 years+ - NCT07286123Recruiting
Vaginoplasty using fish skin graft for transgender women
This trial tests a new surgical technique for gender-affirming vaginoplasty that uses a fish skin graft (Kerecis) to create the vaginal lining. It may be an option for transgender women planning this type of surgery for the first time.
Cleveland, OhioAges 19–99 - NCT06774053Recruiting
The SPECTRA study for transgender and gender diverse people
This study follows transgender and gender diverse people of all ages 16 and older to learn more about their health and well-being over time. It is for those who have a diagnosis of gender incongruence and are either starting, continuing, or have stopped gender affirming therapy.
BaselAges 16 years+ - NCT07480590Recruiting
Gender-Affirming Care and Mental Health Study
This study follows adults who are referred to a gender dysphoria assessment clinic in southern Sweden to see how gender-affirming care affects quality of life, work life, and overall health over time.
Malmö, MalmöAges 18 years+ - NCT07128771Enrolling by invitation
Heart effects of gender-affirming hormone therapy
This study looks at how gender-affirming hormone therapy affects the heart and blood vessels. It aims to understand any changes in heart health for transgender individuals starting or continuing this treatment.
Oslo, OsloAges 16 years+ - NCT06443164Enrolling by invitation
Chronic Pain Treatment Before Gender-Affirming Surgery
This study tests a one-session pain management class called Empowered Relief for people with chronic pain who are planning gender-affirming surgery. The goal is to see if learning these skills before surgery helps with pain afterward.
Portland, OregonAges 18–100 - NCT07772791Recruiting
Online study on digital tools for HIV prevention and treatment in Brazil
This study tests online programs to help people who are at higher risk for HIV get prevention or treatment. It aims to see if digital tools can improve access to and use of HIV medications.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT06800053Recruiting
Support for LGBTQ+ cancer patients and caregivers
This study tests the FOCUS program, a support program designed for sexual and gender minority (LGBTQ+) cancer patients and their unpaid caregivers. It aims to help patients and caregivers cope with cancer through education and emotional support.
Detroit, MichiganAges 18–100 - NCT07718022Recruiting
Dating violence prevention for LGBTQ+ teens and their caregivers
This pilot study tests a program that helps LGBTQ+ teens and their caregivers work together to prevent dating violence. It involves one in-person event in Pittsburgh and online activities.
Pittsburgh, PennsylvaniaAges 14 years+ - NCT06807580RecruitingPhase 2
Adding progesterone to gender-affirming hormone therapy: a study for transgender women
This study tests whether adding progesterone to your current hormone therapy helps transgender women feel better and more satisfied with their treatment. It might be a good fit if you've been on hormones for at least 6 months and haven't used progesterone before.
Atlanta, GeorgiaAges 18–60 - NCT06190613Recruiting
Support program for young men with HIV in Nigeria
This study tests a support program to help young men who have sex with men and transgender women, who are living with HIV, stay engaged in their care and achieve viral suppression (an undetectable HIV viral load). The program may include extra counseling or reminders to help keep your HIV treatment on track.
IbadanAges 15–29 - NCT06436560Enrolling by invitation
Support for transgender and non-binary people seeking vaginoplasty
This study tests a virtual peer support program for transgender and non-binary people who are planning to have vaginoplasty. It aims to see if talking with a trained peer can help with the process.
San Francisco, CaliforniaAges 18 years+ - NCT05794321RecruitingPhase 2
IV tranexamic acid during gender-affirming chest surgery
This Phase 2 study tests whether giving tranexamic acid through a vein during gender-affirming mastectomy can safely reduce bleeding. It may help lower blood loss and related complications during surgery.
San Francisco, CaliforniaAges 18 years+ - NCT06965790Recruiting
Individualized contrast dose CT study for men and women
This trial tests a personalized way to calculate contrast dye for CT scans, based on your sex and body measurements. It may improve safety and image quality.
Augsburg, BavariaAges 18 years+ - NCT06785376Recruiting
HIV testing and PrEP for Black men who have sex with men
This study tests whether a program combining counseling and support can help more Black men in New York City get tested for HIV and start using PrEP or PEP (medicines that prevent HIV). If you are a Black man who has sex with men and are not living with HIV, this trial may be a good fit.
New York, New YorkAges 18–65 - NCT05766592RecruitingPhase 3
Therapy for sexual or gender-minority adults and a rejecting parent
This study tests a therapy program tailored for sexual and gender-minority adults who are dealing with strong rejection from a parent. It also involves that parent in sessions to help improve support and reduce anxiety or depression.
New York, New YorkAges 20 years+
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Common questions
- Are there clinical trials for gender?
- Yes. Clin2 currently lists 105 recruiting gender studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gender trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gender trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.