Clinical trials
Gender clinical trials
Below are recruiting gender clinical trials, each written for real people, not researchers. We’re tracking 102 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06390332Recruiting
Gender affirming care training for college providers
This study is for college health and counseling providers to learn how to better support transgender and gender diverse students. It focuses on training and resources within the RAISE project.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06351501RecruitingPhase 3
Hormone treatment for gender dysphoria in teenagers
This study tests whether hormone therapy (such as testosterone or estrogen) helps reduce distress in teenagers who feel their gender does not match their body. It aims to see if starting hormones at this age improves mental well-being and overall quality of life.
ParisAges 13–14 - NCT06245681Recruiting
How Hormone Therapy Affects the Heart and Liver
This study looks at how cross-sex hormone treatment affects the heart and fat in the liver. It aims to help understand the safety of hormone therapy in transgender individuals.
Vienna, State of ViennaAges 18–99 - NCT06177600Recruiting
TransHealthGUIDE: Health help for gender-diverse young adults
This study aims to improve healthcare for gender-diverse young adults (ages 18-29) and their caregivers. It involves a program to support transgender and nonbinary health and will take place online.
Boston, MassachusettsAges 18–29 - NCT05877391Recruiting
Collecting sexual and gender identity information in hospice
This study tests an approach to collect and use sexual orientation and gender identity (often called “SOGI”) information for people receiving hospice care. The goal is to help hospice teams better understand and support patients’ needs.
Aurora, ColoradoAges 18 years+ - NCT05593692Recruiting
Study of adult emergency visits by age and sex
This study looks at differences in emergency department visits between adults by age and sex. It mainly helps researchers understand patterns of who gets admitted and when.
Rome, LazioAges 18 years+ - NCT05513456Recruiting
ICU doctors and trainees answer a fast online case survey
This study asks intensive care doctors (including trainees) to respond to short ICU case scenarios in a randomized survey. It aims to see whether people’s answers differ by gender and ethnicity, which could help improve fairness and education in ICU decision-making.
StockholmAges Any age - NCT05318755Recruiting
Gender-affirming hormone therapy study for adults starting care
This study looks at starting gender-affirming hormone therapy (GAHT) for transgender people who have never had these treatments before. It may help you learn whether this approach is safe and effective for your goals as you begin care.
Beijing, Beijing MunicipalityAges 18–40 - NCT04979338RecruitingPhase 3
Opioid-sparing pain control for gender-affirming surgery
This Phase 3 study tests ways to manage pain during and after gender-affirming surgery while using less opioid medicine. It may help improve comfort after surgery and reduce opioid-related side effects.
Los Angeles, CaliforniaAges 18 years+ - NCT04935164Recruiting
Study of gender dysphoria versus a control group
This study compares people with gender dysphoria to people without it. It looks at differences in symptoms or outcomes and may help researchers better understand how gender dysphoria affects mental well-being.
PoitiersAges 18–60 - NCT04993469Recruiting
Tracking genital comfort after gender-affirming surgery
This study asks people who are planning genital gender-affirming surgery to report how their genital sensitivity and sexual function feel afterward. It helps doctors understand what changes patients experience and improve follow-up care.
Ghent, East-FlandersAges 18–110 - NCT07825571Recruiting
Gender inclusive sexuality talks program
This study tests a program that helps transgender, gender diverse, or lesbian or bisexual female youth (ages 12-18) and their parents have supportive conversations about sexuality and gender.
Philadelphia, PennsylvaniaAges 12–100 - NCT07480590Recruiting
Gender-Affirming Care and Mental Health Study
This study follows adults who are referred to a gender dysphoria assessment clinic in southern Sweden to see how gender-affirming care affects quality of life, work life, and overall health over time.
Malmö, MalmöAges 18 years+ - NCT07400419Recruiting
Resistance exercise for transgender individuals starting estrogen therapy
This study looks at whether doing resistance training (like lifting weights) can help people who are starting estrogen-based hormone therapy as part of their gender transition. It focuses on how exercise might affect body strength and health during this time.
Boston, MassachusettsAges 18 years+ - NCT04704271RecruitingPhase 1
Study on THC effects in people with past cannabis use
This Phase 1 study looks at how THC (the main mind-altering ingredient in cannabis) affects healthy volunteers shortly after use. It focuses on differences between people and includes those who have used cannabis before.
West Haven, ConnecticutAges 18–55 - NCT07298577Enrolling by invitation
Using blood test and ultrasound to find early liver cancer in Asia
This study tests whether adding a simple blood test (GAAD score) to a routine liver ultrasound can find early-stage liver cancer sooner in people with chronic liver conditions. It aims to improve detection in Asian populations at risk.
Bangkok Noi, BangkokAges 18 years+ - NCT07226401Recruiting
Virtual village for young parents
This study tests a virtual support program for young parents, looking at whether it helps with parenting skills and well-being. If you join, you'll take part in online group sessions with other young parents.
Durham, North CarolinaAges 16–21 - NCT07196930Recruiting
Valvular heart disease in women registry
This study is a registry that collects data on women with valvular heart disease (heart valve problems). It aims to better understand how these conditions affect women and improve their care. You may join if you have a heart valve condition and are treated at a participating center.
AswānAges 18 years+ - NCT07148921Recruiting
Pain perception during gender affirming hormone therapy
This study looks at how starting gender affirming hormone therapy may change your experience of pain. If you are an adult assigned female at birth planning to start testosterone, or an adult assigned male at birth planning to start estradiol, and you have not taken any sex hormones in the past six months, this trial wants to measure your pain perception over time.
Vienna, State of ViennaAges 18 years+ - NCT07133321Enrolling by invitation
Helping husbands support safe hospital births
This trial tests whether a set of programs can help more women give birth in a health facility. It focuses on husbands to encourage their wives to deliver at a hospital or clinic.
Arba Minch, Southern Nations Nationalities Regional StateAges Any age - NCT07109596Recruiting
Frailty prediction for older hospital patients
This study looks at how different factors—like health, mental well-being, and social support—work together to predict frailty in older adults. The goal is to better understand frailty in men and women, which may help doctors provide more personalized care.
RomaAges 56 years+ - NCT07111026Recruiting
Heart health program for farmworker women
This study tests whether community health workers can help farmworker women improve their heart health. It may be a good fit if you work in farming and want to learn how to take better care of your heart.
Ellenton, GeorgiaAges 18–50 - NCT06939257Recruiting
Hormone therapy and pain in gender diverse adults
This study looks at how gender-affirming hormone therapy affects pain in gender diverse (GM) adults. It may help understand whether these hormones change how you feel pain.
Kansas City, KansasAges 18–50 - NCT06969326RecruitingPhase 3
Estrogen cream after hysterectomy for transgender men
This study tests whether using a topical estrogen cream after hysterectomy surgery can help transgender men have a better recovery. Participants will be randomly assigned to use the cream or not, and researchers will follow up by text message.
Providence, Rhode IslandAges 18 years+
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Common questions
- Are there clinical trials for gender?
- Yes. Clin2 currently lists 102 recruiting gender studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gender trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gender trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.