Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,808 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07157774RecruitingPhase 3
Muvalaplin for heart disease in people with high lipoprotein(a)
This study tests a new medicine called muvalaplin that lowers a specific type of cholesterol linked to heart disease. It aims to see if muvalaplin can reduce the risk of future heart attacks, strokes, or related procedures in people with high levels of this cholesterol.
Birmingham, AlabamaAges 18 years+ - NCT06728722Recruiting
Ultrasound for body measurement in critical care
This study uses ultrasound to measure body composition in women admitted to the Obstetrics and Gynecology critical care unit. It aims to see if ultrasound can help assess health status in critically ill patients.
Cairo, Cairo GovernorateAges 16 years+ - NCT07517263RecruitingPhase 3
Long-term Safety Study of Pelacarsen Treatment
This study follows patients who completed an earlier pelacarsen trial to check if the treatment remains safe and well-tolerated over time. Pelacarsen is an experimental medicine being tested for heart and cholesterol health.
Andalusia, AlabamaAges 18–100 - NCT07260253Recruiting
Remote brain stimulation for language in primary progressive aphasia
This study tests if a non-invasive brain stimulation technique called tDCS, done at home with remote supervision, can help improve language skills in people with the logopenic variant of primary progressive aphasia (PPA).
San Francisco, CaliforniaAges 40 years+ - NCT07439289Recruiting
Turtle help during dental visit to reduce child's anxiety
This study uses a calm, supervised turtle interaction to help children feel less anxious during a routine dental visit. It may be a good fit if your child is ages 6-10, generally healthy, and not afraid of turtles.
Iğdır, IğdırAges 6–10 - NCT07027826Recruiting
String test for eosinophilic esophagitis in African patients
This study tests a new, less invasive way (the Esophageal String Test) to look for signs of eosinophilic esophagitis—an allergic condition that can make swallowing painful or difficult. It is for people of African descent who have trouble swallowing and are already having an endoscopy.
Bethesda, MarylandAges 18–65 - NCT06479837Recruiting
Study using tonsil tissue to understand infections
This study uses tonsil tissue that is removed during a routine tonsillectomy to grow tiny 'organoids' in the lab. Researchers will study how germs interact with human cells, which could lead to better treatments for infections.
Bethesda, MarylandAges 2–120 - NCT06948097RecruitingPhase 1
Testing fostamatinib for lung transplant patients with new donor-specific antibodies
This trial tests a drug called fostamatinib to see if it is safe and tolerable for lung transplant patients who develop new antibodies against their donor lung. It aims to prevent rejection without harming the new lung.
Stanford, CaliforniaAges 18–99 - NCT00044122Recruiting
Study of mast cell growth in people with mastocytosis
This study looks at what causes mast cells to grow too much in people with mastocytosis. It may help researchers find better ways to diagnose or treat this condition. You can take part in person or by telehealth.
Bethesda, MarylandAges 1 day–80 years - NCT07804095Enrolling by invitation
AI-supported care program for Medicare Advantage members
This study tests an AI program that helps coordinate care for people with chronic conditions like diabetes, heart failure, or high blood pressure. The goal is to see if it can improve health and reduce costs.
Murray, UtahAges 18 years+ - NCT06414408RecruitingEarly Phase 1
Doxy-PEP study for STI prevention
This trial studies whether giving the antibiotic doxycycline right after sex (known as Doxy-PEP) can prevent STIs. It asks participants to provide hair, blood, and urine samples and follow specific guidelines about hair and condom use.
San Francisco, CaliforniaAges 18 years+ - NCT07802678RecruitingPhase 4
Stopping RA medicines in combination therapy
This study looks at whether people with rheumatoid arthritis who are stable on a TNF inhibitor plus another drug can safely stop the second drug. It aims to see if stopping the extra medicine keeps the disease under control and reduces side effects.
Nijmegen, GelderlandAges 18 years+ - NCT07740343Recruiting
Testing Remimazolam to Improve Sleep After Colorectal Surgery
This study tests a sedative called remimazolam to see if it helps improve sleep after surgery in older adults having colorectal cancer surgery. The goal is to help you sleep better and recover more comfortably.
Yinchuan, NingxiaAges 65–80 - NCT06883305RecruitingPhase 3
Testing tezepelumab for moderate to severe COPD
This trial tests tezepelumab, an injected medication, for people with moderate to very severe COPD who still have flare-ups despite using standard inhalers. It may help reduce flare-ups and improve breathing for those with higher eosinophil levels.
Foley, AlabamaAges 40–80 - NCT06352970Recruiting
TB infection and placenta function study
This study looks at how tuberculosis (TB) infection might affect the placenta and its function during pregnancy. If you are pregnant and giving birth soon, researchers want to learn if TB changes how the placenta grows and works.
Addis AbabaAges 18 years+ - NCT03664609Recruiting
Study of outcomes for people with deep brain stimulation
This study looks back at results for people who have already had deep brain stimulation (DBS) or could get it. It aims to understand how DBS is used and what outcomes people experience.
Phoenix, ArizonaAges Any age - NCT03206099Recruiting
Genetic testing study for people linked to other NIH research
This study collects and sequences (reads) your DNA to help researchers understand health and disease. You may be invited because you are connected to another NIH study, and you must agree to testing, sample storage, and sharing de-identified genetic data for future research.
Washington D.C., District of ColumbiaAges 1 day–100 years - NCT06079567Recruiting
Study of FSHD2 progression over 18 months
This study follows people with FSHD2 over 18 months to learn how the disease progresses and affects daily life. No new drugs are tested—just regular check-ups and an MRI scan.
LeuvenAges 18–75 - NCT05877300RecruitingPhase 1
Test a new esophagus implant to rebuild a short esophagus segment
This Phase 1 study tests the safety and feasibility of a new esophagus implant for people who need only a short (about 6 cm or less) section of their esophagus rebuilt after serious injury or scarring. If it does not work, you must be willing to have a planned “rescue” surgery later.
Los Angeles, CaliforniaAges 18 years+ - NCT05987410Recruiting
Nordic walking for weight and heart health after a cardiac event
This trial tests if a nordic walking program helps people with diabetes who are overweight or obese recover after a heart attack or heart procedure. If you had a heart event or stent/bypass in the last 3 months, this program could help you get stronger and manage your weight.
MilanAges 18 years+ - NCT07230288RecruitingPhase 2
Study of ABBV-142 for Idiopathic Pulmonary Fibrosis
This trial is testing a new antibody drug, ABBV-142, to see if it can reduce disease activity in adults with idiopathic pulmonary fibrosis (IPF). It may help if your IPF was diagnosed within the last 7 years and you meet certain health criteria.
Birmingham, AlabamaAges 40 years+ - NCT07058012RecruitingPhase 2
Testing immunotherapy for ctDNA-positive colorectal cancer after treatment
This trial is for people with colorectal cancer whose ctDNA blood test is still positive after surgery and chemotherapy. It tests two immunotherapy drugs (cemiplimab alone or with fianlimab) to see if they can eliminate the remaining cancer cells and prevent the cancer from coming back.
Gainesville, FloridaAges 18 years+ - NCT06318169RecruitingPhase 3
Testing pegozafermin for MASH and liver fibrosis
This trial tests an experimental drug called pegozafermin to see if it can help people with MASH (a fatty liver disease) and liver scarring (fibrosis). It's for people who have moderate-to-advanced scarring but not cirrhosis, and who have not had other serious liver conditions or poorly controlled diabetes.
Birmingham, AlabamaAges 18–80 - NCT03568669Recruiting
Testing thinking and learning in congenital central hypoventilation syndrome
This study looks at thinking and memory in people with congenital central hypoventilation syndrome (CCHS) to better understand how the condition affects the brain. It may help researchers measure changes over time and guide future care.
Los Angeles, CaliforniaAges 3–85
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,808 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.