Clinical trials
Genetic Disorder clinical trials
Below are recruiting genetic disorder clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06554288RecruitingPhase 1
Trihexyphenidyl for dystonia in cerebral palsy
This study tests how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy, a condition that causes muscle spasms. Researchers want to learn if a child’s genes affect how the medicine works and how the body processes it.
Kansas City, MissouriAges 5–17 - NCT06463223Enrolling by invitation
Liver imaging study for children with obesity
This study uses MRI scans to look at the livers of children with obesity, to find early signs of liver problems. It may help doctors understand how to protect the liver in children.
Gothenburg, Västra Götaland CountyAges 9–14 - NCT06455384Recruiting
Studying a digital tool for genetic testing services
This trial tests a new online tool called the Genetics Navigator, which helps people access genetic testing services more easily. If you or your child have been referred for genetic testing at Mount Sinai Hospital or SickKids in Toronto, this study may help you manage the process online.
Toronto, OntarioAges 18 years+ - NCT03601026Recruiting
Genetic counseling for youth using cannabis safely
This study offers genetic counseling to help reduce mental health problems that can happen for some young people who use cannabis. You join if you are already part of the FORBOW study and fit their age and mental-health criteria.
Halifax, Nova ScotiaAges 12–21 - NCT03718936Recruiting
Study of genetic ADNP conditions in children and adults
This study looks at how people with certain disease-causing changes in the ADNP gene function using medical, genetic, and thinking/behavior assessments. It may help doctors better understand the condition and tailor support for families.
New York, New YorkAges 2 years+ - NCT03718923Recruiting
Study for people with FOXP1 gene changes
This study looks at how people with FOXP1-related neurodevelopmental conditions work and how they’re affected, using genetic, medical, and thinking/learning tests. It may help researchers better understand the condition and improve future care.
New York, New YorkAges 2 years+ - NCT06648044Recruiting
Finding new treatments for kidney ciliopathies
This study aims to find new treatment targets for nephronophthisis and related kidney ciliopathies. Researchers will collect blood and urine samples from people with these conditions, their healthy relatives, and other volunteers to better understand the disease.
La DefenseAges Any age - NCT07278115Recruiting
Gastric bypass with or without nerve-cutting for diabetes
This study compares two types of surgery for people with type 2 diabetes who also have obesity: gastric bypass alone versus gastric bypass plus a procedure called truncal vagotomy (cutting a nerve to the stomach). It aims to see which approach leads to better diabetes remission.
Athens, AtticaAges 18–68 - NCT07055503Enrolling by invitation
Testing a new blood storage system for thalassemia transfusions
This study tests a special system (Hemanext One) that stores red blood cells with less oxygen, to see if it helps people with thalassemia who need regular transfusions. It may reduce side effects or improve how well the transfusions work.
Athens, AtticaAges 18 years+ - NCT07206095Recruiting
Better diagnosis for inherited red blood cell diseases
This trial aims to improve how doctors diagnose rare inherited anemias, including sickle cell disease and other conditions that destroy red blood cells. It may help if you have a confirmed or suspected diagnosis but need more clarity through advanced testing.
Barcelona, BarcelonaAges Any age - NCT05480826Recruiting
Family genetic study for mood, thinking, and autism conditions
This study looks at genetic changes found in people with conditions like bipolar disorder, schizophrenia, depression, or autism, and compares how those genetic differences may function. It may help researchers understand the causes of these conditions using information from patients and their relatives.
CréteilAges 18 years+ - NCT02450851Recruiting
Find answers for undiagnosed medical conditions using genetic testing
This study helps look for causes of health problems when no one has been able to give a diagnosis. It tests and shares medical and genetic information (with privacy protections) so researchers can better match findings to possible causes.
Birmingham, AlabamaAges 1 month–100 years - NCT02014246Recruiting
Genetic study of movement disorders and dementia
This study looks at DNA (genetic material) in people with movement disorders or dementia, and in some family members or healthy volunteers. The goal is to better understand why these conditions happen and how genes may contribute.
Baltimore, MarylandAges 18–120 - NCT06584994Enrolling by invitation
Genetics and cancer risk in families
This study looks at how genes passed down in families might increase the chance of getting cancer. It collects samples from children with cancer and their family members to better understand cancer risks.
CambridgeAges Any age - NCT05649098RecruitingEarly Phase 1
Testing dupilumab for itchy inherited genetic skin disorders
This early trial tests whether dupilumab can reduce itching in people with certain inherited (genetic) inflammatory skin conditions. It may help by calming skin inflammation that causes ongoing itch and sleep problems.
Chicago, IllinoisAges 6 months+ - NCT06725901Recruiting
Platform to support genetic diagnosis in children
This trial is building a platform to help doctors diagnose rare genetic diseases in children. It asks neuropediatricians at a specific hospital to share their experience and help improve the process of referring kids to genetic specialists.
Valparaíso, ValparaisoAges Any age - NCT01601171Recruiting
Genetic study of reproductive problems and cleft lip or palate
This study looks at genetic (inherited) causes of certain hormone and reproductive conditions, including Kallmann syndrome and cleft lip/palate. You might be asked for medical and family history and possibly a DNA sample, helping researchers find what drives these conditions.
Lausanne, Canton of VaudAges Any age - NCT06072079Enrolling by invitation
Structural chromosome changes and brain disorders
This trial is for people who have or might have a rare disease or a change in their chromosomes. The study aims to learn more about how these changes relate to brain disorders.
StockholmAges Any age - NCT00001215Enrolling by invitation
Understanding Genetic Lysosomal Storage Disorders
This study aims to understand genetic factors in lysosomal storage disorders—rare conditions where the body cannot break down certain substances. Researchers will collect information from patients with these disorders, their family members, and healthy volunteers to learn how these diseases develop and affect people over time.
Bethesda, MarylandAges 1 week–110 years - NCT06368726Enrolling by invitationPhase 1
Brain stimulation for kids with autism and genetic changes
This trial tests a gentle brain stimulation treatment called tDCS for children with autism or related conditions who also have certain genetic changes. It may help improve symptoms if your child meets the specific health and birth history requirements.
Albuquerque, New MexicoAges 6–11 - NCT07654179Recruiting
Metformin for depression with obesity: a genetic study
This trial tests if adding metformin to antidepressants helps people who have both depression and obesity. It also looks at genetic factors that might affect treatment response.
Rawalpindi, Punjab ProvinceAges Any age - NCT06555965Recruiting
STXBP1 and SYNGAP1 natural history study
This study follows people with STXBP1 or SYNGAP1 gene changes over time to learn more about how these conditions affect the body and mind. It does not test a treatment but helps researchers understand the natural course of the disorder.
Palo Alto, CaliforniaAges Any age - NCT00001467Recruiting
Study of genes in immune disorders
This research looks at how inherited (genetic) changes may affect the immune system in people with immune problems. It may help by improving understanding of these conditions and, in some cases, guiding faster care for a baby after birth.
Bethesda, MarylandAges 1 day–101 years - NCT06953180Recruiting
Epigenetics, aging, and disease prevention study in Kazakhstan
This study looks at how your genes and environment affect your risk for non-communicable diseases like heart disease or diabetes. It aims to predict your biological age and help create personalized prevention plans.
Almaty, KazakhstanAges 18–69
Hear when a new Genetic Disorder trial opens
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Common questions
- Are there clinical trials for genetic disorder?
- Yes. Clin2 currently lists 91 recruiting genetic disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetic disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetic disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.