Clinical trials
Genetic Change clinical trials
Below are recruiting genetic change clinical trials, each written for real people, not researchers. We’re tracking 12 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07174336RecruitingPhase 3
Testing Tersolisib with other treatments for advanced breast cancer
This trial tests a new study drug called Tersolisib combined with other anti-cancer treatments for people with advanced breast cancer that has a specific gene change (PIK3CA). The goal is to see if the combination can help shrink or slow the cancer.
Anchorage, AlaskaAges 18 years+ - NCT06659341RecruitingPhase 1
Study of BAY3498264 with Sotorasib for KRAS G12C Cancers
This trial tests a new drug (BAY3498264) combined with sotorasib, a targeted therapy, for people with advanced cancers that have a specific genetic change called KRAS G12C. It's for those who have already tried other treatments and need new options.
Albury, New South WalesAges 18 years+ - NCT01238250Recruiting
Online autism genetics study for families with certain genetic changes
This study asks people with specific genetic changes linked to autism and their family members to complete online tasks and questionnaires. It may help researchers better understand how these genetic differences relate to autism traits.
Boston, MassachusettsAges Any age - NCT05010031RecruitingPhase 2
Lower-dose radiation for metastatic cancer with an ATM mutation
This trial tests whether giving a lower dose of radiation can help control metastatic tumors that carry a specific genetic change in the ATM gene. It may reduce side effects by using less radiation, while still aiming to keep the tumor under control.
Basking Ridge, New JerseyAges 18 years+ - NCT05398380Recruiting
Liver transplant for colorectal liver cancer that can’t be removed
This trial studies liver transplantation for certain people with colorectal cancer that has spread only to the liver and cannot be removed with surgery. It aims to improve outcomes for carefully selected patients whose cancer is controlled on chemotherapy and who meet specific safety and scan requirements.
Barcelona, BarcelonaAges 18–70 - NCT06777875Recruiting
How genes affect pain after surgery in children
This trial looks at how certain genes may affect how children feel pain after surgery. The goal is to understand if differences in your DNA can help doctors manage pain better for each child.
BeirutAges 8–18 - NCT06252922Recruiting
How diet changes genetic material in healthy young men
This study looks at how diet can change genetic material in healthy young men. You would eat prepared meals, wear a glucose monitor, and give blood and sperm samples to help researchers understand these effects.
Baton Rouge, LouisianaAges 20–35 - NCT07014501Recruiting
Stroke recovery and trach tube removal at different altitudes
This trial studies how well stroke patients with a breathing tube (tracheostomy) can have it removed. It looks at genes and blood oxygen levels, and compares patients at different altitudes to find the best timing for removal.
Kunming, YunnanAges 18–75 - NCT07178704Recruiting
Genes and metabolism after weight loss surgery
This study looks at how your genes and metabolism affect changes in body composition after weight loss surgery. It aims to understand why some people lose more weight or gain muscle differently than others.
Galveston, TexasAges 18–65 - NCT07738003Recruiting
Perinatal Autism Genetics and Epigenetics Study
This study looks at genetics and other factors that may be linked to autism. Pregnant women in their first or second trimester are invited to join, and their babies will be followed to see how they develop.
Iowa City, IowaAges birth–50 years - NCT07345338Enrolling by invitation
Genetic testing for non-ischemic heart muscle disease
This study offers genetic testing to adults with a type of heart muscle disease (non-ischemic cardiomyopathy or dilated cardiomyopathy) that is not caused by blocked arteries. The goal is to find genetic causes, which may guide treatment and family screening.
Calgary, AlbertaAges 18 years+ - NCT05765864Recruiting
Study of self-harm in at-risk teens
This study looks at self-harm and thoughts/behaviors related to safety in teenagers who are considered at higher risk. It may help researchers better understand what supports are needed for teens who self-harm without wanting to die.
LjubljanaAges 13–18
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Common questions
- Are there clinical trials for genetic change?
- Yes. Clin2 currently lists 12 recruiting genetic change studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetic change trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetic change trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.