Clinical trials
Genetic Predisposition to Cancer clinical trials
Below are recruiting genetic predisposition to cancer clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05463796Recruiting
Prevention and early detection for people at high cancer risk
This study looks at surveillance (watching closely), prevention, and early “interception” steps to lower the chance that cancer will develop or be found later. It is for people with genetic risk, past cancer treatment exposures, strong family history, or certain early pre-cancer or high-risk conditions.
Boston, MassachusettsAges Any age - NCT05849155Recruiting
Talking study for teens with inherited cancer risk
This study looks at how parents and children communicate after learning about an inherited (genetic) cancer risk. It may help researchers find better ways to support families in these conversations.
Memphis, TennesseeAges 10–24 - NCT06089421Recruiting
Genetic information assistant for cancer risk testing
This study tests a tool called GIA (Genetic Information Assistant) that helps people understand genetic testing for cancer risk. You would use the tool on a smartphone or computer during a genetic counseling session.
Charlottesville, VirginiaAges 18 years+ - NCT07456904Recruiting
Transition to adult care for cancer risk patients
This study looks at how young adults with a genetic risk for cancer (cancer predisposition syndrome) transition from St. Jude children's care to adult healthcare. It aims to understand their health outcomes and help improve future care.
Memphis, TennesseeAges 18 years+ - NCT06450171Recruiting
Multi-cancer early detection test for people at high risk
This study tests a blood-based multi-cancer early detection (MCED) screening test in people with a high risk of cancer due to inherited gene changes or strong family history. The goal is to see if this test can find cancer early.
Boston, MassachusettsAges 22 years+ - NCT07228000Recruiting
Cancer screening and genetic services navigation for Black and Hispanic women
This study helps Black and Hispanic women ages 45-74 get both breast and colorectal cancer screenings and genetic services. It provides a navigator to guide you through the process.
Newark, DelawareAges 45–74 - NCT06800599Enrolling by invitation
Cancer genetic risk assessment registry
This study collects information from people who receive genetic counseling for cancer risk. Joining the registry helps researchers learn more about cancer genetics and improve future care.
Bologna, ItalyAges Any age - NCT04141462Recruiting
Genetic testing study for early cancer risk
This study looks at whether DNA (from a tumor or related samples) can help identify inherited cancer risk in people who develop cancer at a young age. It may help families learn more about risk factors and guide future screening or prevention.
BesançonAges 18 years+ - NCT04702321Recruiting
Study genetic risks for childhood cancer complications in Switzerland
This study looks at genetic factors to understand why some children who had cancer develop later complications. It uses stored samples and information from a Swiss biobank to help researchers identify higher-risk children.
GenevaAges Up to 21 years - NCT04763317Recruiting
Precision medicine for prostate cancer care decisions
This study tries to personalize prostate cancer care by matching treatment decisions to a person’s specific risk profile. You might be able to join if you have certain types of prostate cancer or a strong family history and meet health-function requirements.
Sutton, EnglandAges 30–70 - NCT04903782Recruiting
Family whole-genome testing for children with newly diagnosed cancer
This study offers whole-genome testing (a way to read a person’s DNA) to families after a child is newly diagnosed with cancer. It aims to find inherited changes that may explain why cancer happened and guide future care or monitoring.
Newcastle, New South WalesAges Up to 21 years - NCT05020574RecruitingPhase 2
Study how the microbiome may affect breast implant infections
This Phase 2 study looks at whether changes in the body’s “microbiome” (the normal germs in and on the body) are linked to infections after breast surgery with implants. It may help doctors better predict and prevent implant infections in people undergoing mastectomy with immediate implant placement.
San Francisco, CaliforniaAges 18 years+ - NCT05350761Recruiting
Study rare tumors and inherited cancer risk in families
This study looks at people who have rare or unusual cancers or who may have an inherited (family) risk for cancer. It helps researchers learn what genetic or other factors might be involved by collecting family history and medical records, including pathology slides.
Bethesda, MarylandAges Any age - NCT05587439Recruiting
Study of inherited genetic risk in lung and related cancers
This study looks for inherited (family-passed) genetic changes that may raise the risk of lung cancer and related thoracic cancers. It may help people and families understand their genetic risk by collecting health information and sometimes specimens from patients and relatives.
Boston, MassachusettsAges 18 years+ - NCT07378423Recruiting
Survey on signs of cancer at birth
This trial asks newly diagnosed children and young adults with certain types of cancer to fill out a questionnaire about signs of cancer present at birth. The answers may help improve early detection of childhood cancer.
BernAges Up to 21 years - NCT01441089Recruiting
Donate blood for genetic testing in an NIH research study
This study collects blood from people already in an NIH (National Institutes of Health) clinical research program to run genetic tests. It may help researchers understand cancer and related inherited conditions by studying DNA changes.
Bethesda, MarylandAges 3 years+ - NCT06659614Recruiting
Prostate tissue collection for future cancer research
This study collects prostate tissue samples from men who are either at higher risk due to a gene change or are getting a biopsy or prostate surgery for routine care. The samples are stored in a biobank for future research on prostate cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06584994Enrolling by invitation
Genetics and cancer risk in families
This study looks at how genes passed down in families might increase the chance of getting cancer. It collects samples from children with cancer and their family members to better understand cancer risks.
CambridgeAges Any age - NCT06470685Enrolling by invitation
Preventive prostate removal for prostate cancer risk
This study tests whether removing the prostate before cancer develops can help people at higher risk, such as those with certain gene changes (like BRCA2), a strong family history, or Black African/Caribbean ancestry. It also includes people who have already had their prostate removed for cancer treatment.
LondonAges 18 years+ - NCT05129605Recruiting
Prostate cancer genetic risk screening study for men
This study looks at your personal and family risk for prostate cancer and helps decide who should have extra screening like MRI. It may help you find cancer earlier if you are at higher genetic risk.
Boston, MassachusettsAges 35–74 - NCT06680791Recruiting
Endometrial cancer study on recurrence prevention and lifestyle
This study looks at how your cancer type and daily habits might help prevent endometrial cancer from coming back. It only requires that you've had endometrial cancer and a hysterectomy.
PragueAges Any age - NCT06962059Recruiting
Healthy volunteers with ovaries needed for study
This study is looking for healthy volunteers who still have their ovaries and have not had cancer or certain genetic mutations. Researchers want to learn more about ovarian health.
Philadelphia, PennsylvaniaAges 30–50 - NCT07264790RecruitingPhase 1
Minoxidil for Better Blood Flow in Breast Reconstruction
This trial tests whether applying minoxidil (a hair growth medication) to breast tissue during surgery can improve blood flow to the reconstructed breast. It is for women who are having both breasts removed to prevent cancer and have reconstruction on the same day.
Durham, North CarolinaAges 18 years+ - NCT01689584Recruiting
Study of genetic variants in cancer families
This study looks at how a specific DNA genetic change (variant) runs within cancer families. It may help researchers better understand cancer risk and improve genetic testing and interpretation.
Bastia, CorsicaAges 18 years+
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Common questions
- Are there clinical trials for genetic predisposition to cancer?
- Yes. Clin2 currently lists 50 recruiting genetic predisposition to cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetic predisposition to cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetic predisposition to cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Genetic Predisposition
- Non Small Cell Lung Cancer
- Genetic Predisposition to Disease
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Cancer Predisposition Syndrome
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.