Clinical trials
Genetic Predisposition to Cancer clinical trials
Below are recruiting genetic predisposition to cancer clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01689584Recruiting
Study of genetic variants in cancer families
This study looks at how a specific DNA genetic change (variant) runs within cancer families. It may help researchers better understand cancer risk and improve genetic testing and interpretation.
Bastia, CorsicaAges 18 years+ - NCT03396341Recruiting
Surveys after genetic risk results for certain breast cancer genes
This study asks women to complete surveys after learning their genetic risk results for certain breast cancer–related gene changes. It helps researchers understand how people respond and what they think or feel after getting these results.
Boston, MassachusettsAges 25 years+ - NCT00050752Recruiting
Study of hereditary kidney cancer and skin tumors
This research study helps doctors understand a rare genetic condition called HLRCC that causes specific types of skin tumors and kidney cancer to run in families. By studying your genetics and medical history, researchers hope to improve how doctors detect and treat this condition.
Bethesda, MarylandAges 2 years+ - NCT05929976Recruiting
Study of gut and blood chemistry in children with new leukemia
This study looks at the gut microbiome (tiny organisms in the gut) and metabolome (small chemicals in the body) in children and teens with newly diagnosed ALL. It may help researchers understand what is happening in the body early in treatment and could guide future, more personalized care.
New York, New YorkAges 3–18 - NCT06792721Recruiting
Measuring mutation levels in siblings with BRCA risk
This study looks at how genetic mutations (changes in DNA) are measured in the blood of sisters. One sister has a BRCA1 or BRCA2 gene mutation that raises cancer risk, and the other does not. The goal is to understand mutation differences between them.
Caen, FranceAges 30–50 - NCT02543905Recruiting
Profile study for men at higher prostate cancer risk
This trial looks at how inherited risk (family history or gene findings) relates to screening and treatment for prostate cancer. If you qualify, you may be offered prostate screening tests and follow-up to see how well risk information predicts next steps.
Sutton, SurreyAges 40–69 - NCT03667417Recruiting
Study of people with BRCA1/BRCA2 cancer gene changes
This study follows people who carry a harmful BRCA1 or BRCA2 gene mutation, whether or not they currently have breast or ovarian cancer. The goal is to better understand cancer risk over time and how being a carrier may affect screening and care.
MarseilleAges 18 years+ - NCT06917794Enrolling by invitation
Genetic risk study for colon cancer patients
This study looks at how your genetic background and ancestry affect your risk for colon cancer. If you have been diagnosed with colon cancer and have a tumor sample available, you may be able to help researchers develop better risk scores.
Fortaleza, CearáAges 18 years+ - NCT04970056Recruiting
Pancreatic cancer risk and early-detection registry study
This study builds a database of people at higher risk for pancreatic cancer (or certain early warning findings) to help find better ways to detect the disease early. You may be asked to complete health questionnaires and possibly donate a blood/saliva/swab sample.
Phoenix, ArizonaAges 18–90 - NCT04419896Enrolling by invitation
Patient registry for people who had genetic testing
This registry collects past and ongoing health and genetic testing information from adults who have had germline or other genetic/blood biomarker tests. It helps researchers learn patterns that may improve cancer care in the future.
Redding, CaliforniaAges 18 years+ - NCT04511806Recruiting
Study of inherited cancer risk in children and families
This study looks at how inherited “cancer predisposition” conditions run in families, even if a child has not had cancer yet. It may help doctors better understand who is at higher risk and guide future monitoring or care.
Atlanta, GeorgiaAges Any age - NCT06523179Recruiting
Liver cancer risk study for people with fatty liver disease
This study looks at your risk of developing liver cancer (hepatocellular carcinoma) if you have a liver condition such as NAFLD or a related disease. It aims to improve how doctors predict who might be at higher risk, so they can offer better monitoring and care.
Milan, MilanoAges 45–75 - NCT04431024Recruiting
Testing imaging and biopsy options for people with BAP1 risk
This study looks at how well advanced scans, liquid biopsy tests, and small follow-up procedures can find early mesothelioma in people with a high-risk BAP1 gene condition. It may help catch cancer earlier when treatment could work better.
Bethesda, MarylandAges 30–120 - NCT00033137Recruiting
Genetic study of Birt-Hogg-Dubé syndrome and kidney cancer risk
This research study examines the genes behind Birt-Hogg-Dubé (BHD) syndrome, a condition that increases kidney cancer risk. Researchers want to understand who inherits this condition and how to better identify and help people at risk.
Bethesda, MarylandAges 2 years+ - NCT03568630Recruiting
Blood tests to study early pancreatic cancer risk
This study looks at blood “markers” to find early signs or higher risk for pancreatic cancer. You may join if you have certain risk factors (like new diabetes, pancreatic cysts/pancreatitis, or a strong family history) and can come to Omaha for blood draws twice a year.
Omaha, NebraskaAges 19 years+ - NCT05746182Recruiting
Genetic testing program for pancreatic neuroendocrine tumors
This study offers genetic (inherited) testing for people with pancreatic neuroendocrine neoplasms. The goal is to see who may have a genetic predisposition, which can help guide medical care and family risk.
Los Angeles, CaliforniaAges 18 years+ - NCT03050268Recruiting
Study of childhood cancer risk in families
This study looks at inherited (family) risk for childhood cancers, including families with early cancers or known cancer risk conditions. It may help researchers understand why some children get cancer and improve future risk detection and care.
Memphis, TennesseeAges Any age - NCT06003153RecruitingPhase 4
Gene and sugar response study with oral semaglutide
This study looks at how your genes affect your body's response to a diabetes medication called semaglutide. It may help people with slightly high blood sugar (pre-diabetes) understand why some respond better than others.
Boston, MassachusettsAges 18–65 - NCT06226194Recruiting
Genes and weight loss after bariatric surgery
This study looks at how your genes might affect how much weight you lose after gastric sleeve or gastric bypass surgery. You may be able to help doctors better predict weight loss results for future patients.
Lleida, LeidaAges 18–65 - NCT01247597Recruiting
Study of DICER1-related tumor history in families
This study follows people affected by DICER1-related tumors (and sometimes family members) to better understand how these conditions develop over time. It may help families by improving knowledge and guiding genetic counseling and future care.
Bethesda, MarylandAges 1 month–99 years - NCT06456320Enrolling by invitation
Mayo Clinic Tapestry 2.0: Multi-Omics Health Discovery
This study uses advanced testing (called multi-omics) to look at your genes, proteins, and other molecules to discover new things about health and disease. You'll need to be a Mayo Clinic patient, able to receive packages, and not have a history of blood cancer or a donor bone marrow transplant.
Scottsdale, ArizonaAges 18 years+ - NCT07332598Enrolling by invitation
Mayo Clinic precure study for prevention of blood cancers
This study aims to learn how to prevent blood cancers. You will provide samples over time so researchers can look for early signs of cancer.
Rochester, MinnesotaAges 18 years+ - NCT06447961Recruiting
Psychological impacts of living with inherited colorectal cancer risk
This study explores how people feel emotionally and mentally when they have a genetic condition that raises their risk of colorectal cancer. It aims to understand the psychological effects, which could help improve support for others in the future.
LondonAges 18–99 - NCT07018128Recruiting
Breathing technique for lowering blood pressure in Thai adults
This study tests whether a simple breathing technique (the 4-7-8 method) can help lower blood pressure. It looks at how certain genes might affect the results, and includes people with normal or high blood pressure in eastern Thailand.
MueangChonburi, Changwat Chon BuriAges 18–59
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Common questions
- Are there clinical trials for genetic predisposition to cancer?
- Yes. Clin2 currently lists 51 recruiting genetic predisposition to cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetic predisposition to cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetic predisposition to cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Genetic Predisposition
- Non Small Cell Lung Cancer
- Genetic Predisposition to Disease
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Cancer Predisposition Syndrome
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.