Clinical trials
Genetics clinical trials
Below are recruiting genetics clinical trials, each written for real people, not researchers. We’re tracking 705 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06314607Recruiting
Genetic study of brain lesions
This trial looks at the genetic and molecular features of brain lesions to better understand them. It may help find new ways to diagnose or treat these conditions.
ParisAges 18 years+ - NCT06321822Recruiting
Genetic diagnosis and personalized medicine for epilepsy patients
This study aims to find genetic causes of epilepsy and use that information to personalize your care. It involves analyzing your DNA to look for gene changes that may be linked to your seizures.
MilanAges Any age - NCT07653412Recruiting
Genetic test for predicting weight loss drug response
This trial looks at whether your genes can predict how well you will respond to weight loss medications like semaglutide (Wegovy/Ozempic) or tirzepatide (Mounjaro). It may help doctors choose the right drug for you based on your DNA.
AthensAges 18 years+ - NCT07178704Recruiting
Genes and metabolism after weight loss surgery
This study looks at how your genes and metabolism affect changes in body composition after weight loss surgery. It aims to understand why some people lose more weight or gain muscle differently than others.
Galveston, TexasAges 18–65 - NCT06329739Recruiting
Genetics and thinking in Parkinson's disease
This study looks at how certain genes might affect thinking and behavior in people with Parkinson's disease. If you have Parkinson's, take Parkinson's medication, and have had genetic testing, you may be able to join.
MilanAges 18 years+ - NCT06334588Recruiting
Autism brain study using MRI and social thinking tasks
This study uses MRI brain scans (already needed for medical reasons) to better understand how autism affects social thinking. It compares people with autism to healthy volunteers to see differences in brain activity.
ParisAges 3 months–28 years - NCT06337864Recruiting
Large neutral amino acids for adults with classical PKU
This study tests whether a specific mix of large neutral amino acids (LNAAs) can help adults with classical PKU by lowering phenylalanine levels in the brain. It includes an MRI and PET scan to see how the treatment affects brain activity.
CopenhagenAges 18–50 - NCT06353607Recruiting
Genetics of aortic aneurysm and dissection
This study looks at the genetic reasons behind aortic aneurysms and sudden aortic tears. By studying people who had surgery at the University Hospital Basel, researchers hope to find inherited patterns that could help predict and prevent these serious conditions.
BaselAges 18 years+ - NCT06372587Recruiting
Next-generation Alzheimer's treatment study
This study tests a new treatment for people with probable Alzheimer's disease. It aims to see if the treatment is safe and effective for patients between 18 and 80 years old.
RomaAges 18–80 - NCT06374719Recruiting
TNNT1 myopathy natural history study
This study follows people with a rare genetic muscle condition called TNNT1 myopathy over time. Researchers will track how the disease progresses to better understand it and help plan future treatments.
Gordonville, PennsylvaniaAges Any age - NCT06377033Recruiting
Using health records to advance genomic medicine for all
This study uses electronic health records to learn how to improve genomic medicine across a diverse health system. It may help make DNA-based healthcare more accessible and effective for people with certain conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06393894Recruiting
Latvian Early Atherosclerosis Registry Study
This study is gathering information from people with early heart artery blockages (occurring before age 55 for men or 65 for women) who need or have had treatment like stents or bypass. It helps doctors understand long-term outcomes.
RigaAges 18–65 - NCT06399666Recruiting
Inflammation markers and genes in atrial fibrillation prediction
This trial looks at whether certain blood markers and genetic information can help predict atrial fibrillation (irregular heartbeat). It studies how inflammation might play a role, and aims to find better ways to identify people at risk.
Jönköping, SmålandAges 18 years+ - NCT06435585Recruiting
Heart failure genetics and response study
This study looks at how genes affect heart failure treatment response. It uses blood samples to find new markers that may help predict who will benefit most from therapy.
StockholmAges 18 years+ - NCT06441942Recruiting
Women with heart attack or unstable angina study
This study is a registry that collects information about women who have had a heart attack or unstable angina. The goal is to learn more about how these conditions affect women and improve care for women with heart disease.
Milan, Italy MilanAges 18–100 - NCT06441955RecruitingPhase 4
Long Covid prevention and health support trial
This trial tests a care program designed to help people who continue to have symptoms after recovering from COVID-19. It aims to prevent long-term health problems and improve well-being.
Bethesda, MarylandAges 18–65 - NCT06442033Recruiting
Exercise and genetics to slow Parkinson's
This trial studies whether a regular aerobic cycling program can slow the progression of Parkinson's disease. Researchers will also look at how genetics may affect the benefits of exercise.
Cleveland, OhioAges 18 years+ - NCT06446271Recruiting
Biomarkers in Scottish Cardiomyopathy Registry
This study looks for signs of heart muscle disease (cardiomyopathy) in people who have certain genetic changes. It aims to find better ways to monitor and treat the condition.
GlasgowAges 10 years+ - NCT06449989Recruiting
Comparing genetics of colorectal cancer and its brain spread
This study compares the genetics of the original colorectal cancer with the cancer that has spread to the brain. It aims to understand how the tumor changes when it metastasizes, which may help guide future treatments.
Moscow, MoscowAges 18 years+ - NCT06475651Recruiting
DNA patterns in rare prenatal diseases
This study looks at DNA patterns in fetuses or children with rare genetic conditions. It aims to better understand how these patterns relate to diseases that start before birth, which could help with diagnosis and future care.
ParisAges birth–18 years - NCT07062588RecruitingPhase 2
AGA2115 for osteogenesis imperfecta in adults with COL1A1/COL1A2 variations
This trial tests a new drug called AGA2115 for people with osteogenesis imperfecta (also known as brittle bone disease) who have a confirmed genetic change in the COL1A1 or COL1A2 genes. The study aims to see if the drug can help strengthen bones and reduce fracture risk.
Phoenix, ArizonaAges 18–75 - NCT05890911Enrolling by invitation
Studying dopamine pathways in breathing problems during sleep
This study looks at how dopamine-related brain pathways may be involved in sleep-related breathing problems. It may help researchers better understand what causes these conditions and how to evaluate them with sleep testing.
WroclawAges 18–80 - NCT06490627RecruitingPhase 2
thalidomide for transfusion-dependent beta thalassemia
This trial tests different doses of thalidomide to see if it can reduce or eliminate the need for blood transfusions in people with beta thalassemia major or intermedia.
Karachi, SindhAges 8–35 - NCT06504433Recruiting
Natural history of mitochondrial diseases
This study follows people with mitochondrial disease over time to learn more about how the condition progresses. It may help researchers find better ways to manage and treat mitochondrial diseases in the future.
Randwick, New South WalesAges 18 years+
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Common questions
- Are there clinical trials for genetics?
- Yes. Clin2 currently lists 705 recruiting genetics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.