Clinical trials
HIV clinical trials
Below are recruiting hiv clinical trials, each written for real people, not researchers. We’re tracking 611 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05413122RecruitingPhase 2/Phase 3
Smoking quit support for adults living with HIV in South Africa
This trial tests smoking-cessation interventions to help people living with HIV quit smoking or smoke less. You may be eligible if you smoke, are actively engaged in HIV treatment, and can follow the study for about a year.
Soweto, GautengAges 18 years+ - NCT07125235Recruiting
Support program for HIV treatment adherence
This trial tests a program to help people with HIV stay on track with their medication. If you take HIV medication, sometimes miss doses, and use stimulants, this program may offer support to improve your health.
San Francisco, CaliforniaAges 18–70 - NCT00114647Recruiting
Blood draw to collect plasma or white blood cells for lab tests
This trial uses a special blood-removal procedure called apheresis to collect either plasma or white blood cells for laboratory research. It may help scientists understand infection or immune-related processes by providing specific blood components for study.
Bethesda, MarylandAges 18–100 - NCT07030075Recruiting
Flu and respiratory infection study in Lusaka
This study looks at flu-like symptoms and other respiratory infections in adults in Lusaka, Zambia. It aims to understand how these infections affect people with and without HIV, and may help improve care.
Lusaka, Lusaka ProvinceAges 18 years+ - NCT05069688RecruitingPhase 1
Testing dolutegravir dosing in HIV and TB children
This study looks at the right way to dose dolutegravir (an HIV medicine) in young children who also have active tuberculosis (TB). Doctors will measure how the medicine moves through the body, especially when standard vs higher-dose rifampicin is used.
Ibadan, Oyo StateAges 4 weeks–5 years - NCT07227779RecruitingPhase 2
B-PaLMZ for TB meningitis in people with HIV
This trial tests a combination of TB medicines (B-PaLMZ) for people with HIV who have their first episode of TB meningitis. It aims to find a better treatment option.
KampalaAges 18 years+ - NCT07727642Recruiting
Optimizing HIV Medicines for AIDS-Related Lymphoma
This trial helps doctors find the best way to combine HIV medicines (antiretroviral therapy) with lymphoma treatment for people who have both HIV and AIDS-related lymphoma. The goal is to improve your overall care and outcomes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06666322RecruitingPhase 2/Phase 3
Treating cryptococcal meningitis in people with HIV
This trial is testing new treatments for cryptococcal meningitis, a serious brain infection, in people living with HIV. It aims to find the best way to treat this infection with fewer side effects.
KampalaAges 18 years+ - NCT05561595Recruiting
Reducing health-related stigma through group support
This trial tests a virtual group program to help people cope with health-related stigma from conditions like obesity, cancer, HIV, diabetes, skin disease, or chronic pain. It aims to reduce internalized stigma and improve well-being.
Gainesville, FloridaAges 18 years+ - NCT05729256Recruiting
Study on alcohol and impulsive sexual choices in gay men
This study looks at how heavy drinking may affect “heat of the moment” sexual decisions and related thinking. You may be able to take part if you meet specific recent sex and drinking criteria.
Boston, MassachusettsAges 18 years+ - NCT07711223RecruitingPhase 1/Phase 2
New HIV pill compared to standard treatment for untreated adults
This trial compares a new HIV medication (ACC017) to an existing one (dolutegravir) in adults who have HIV but have never taken HIV drugs before. The goal is to see if the new pill works as well and is safe.
BeijingAges 18 years+ - NCT06880705Recruiting
Trans-Led Care Study for alcohol and drug support
This study is testing a program designed by and for transgender adults to help with alcohol or drug use problems. It looks at whether a supportive, community-based approach can improve health and well-being.
Chicago, IllinoisAges 18 years+ - NCT03300830Recruiting
Testing tumors linked to viruses, HIV, and immune disorders
This study collects and analyzes tumor tissue to learn what drives certain cancers and growths linked to viruses, HIV, and immune system problems. Results may help researchers understand disease causes and point to better future treatments.
Bethesda, MarylandAges 18 years+ - NCT03878121RecruitingPhase 1
Ad4-HIV vaccine study for healthy adults and partners
This Phase 1 study tests whether an experimental HIV vaccine (made from a harmless viral vector) is safe and helps the body build immune defenses. It includes healthy volunteers and, in some groups, their close partners, with careful screening and follow-up visits.
Bethesda, MarylandAges 18–65 - NCT04052022Recruiting
Study of TB flare-ups in people without HIV
This study looks at why some people with tuberculosis (TB) get worse or develop new inflammation after they initially start improving on treatment—called a “paradoxical reaction.” It collects blood and tissue samples to better understand these flare-ups and guide future care.
Bethesda, MarylandAges 18–99 - NCT04319367RecruitingPhase 2
Antibody treatment added to HIV meds for early HIV
This Phase 2 trial tests whether adding long-acting HIV antibodies to standard HIV treatment (ART) can help control HIV in people who started ART soon after getting infected. It also checks how safe the antibody treatment is and how well it works over time.
AarhusAges 18–60 - NCT04499053RecruitingPhase 2
Durvalumab and tremelimumab with chemotherapy for advanced lung cancer in HIV
This trial tests a combination of immune therapy drugs (durvalumab and tremelimumab) given with chemotherapy in people with stage IV non-small cell lung cancer who also have HIV. It may help shrink or control cancer by boosting the immune response while keeping HIV well controlled.
Washington D.C., District of ColumbiaAges 18 years+ - NCT04512456Recruiting
Exercise training study for people with HIV and heart health
This study looks at how a structured exercise program affects the heart and blood flow in people living with HIV. It may help your care team understand who benefits most from exercise and how to do it safely.
Rio de Janeiro, Rio de JaneiroAges 30–50 - NCT04521803RecruitingPhase 2
Higher-dose rifampicin for TB fluid around the heart
This Phase 2 study compares a higher dose versus the standard dose of rifampicin, a TB antibiotic, for people with TB-related fluid buildup around the heart. It aims to see which dose works better and is safe in improving TB pericarditis with fluid.
Mthatha, Eastern CapeAges 18 years+ - NCT04667026Recruiting
Study of people living with HIV on treatment
This is an observational study that follows people with HIV who are taking HIV medicines (antiretroviral therapy). It may help researchers understand how treatment is going and what factors relate to doing well on therapy.
Guangzhou, GuangdongAges 14 years+ - NCT04760574Recruiting
HIV status and low testosterone in men
This study looks at whether low testosterone (often called male hypogonadism) is linked to having HIV. It compares HIV-positive men with HIV-negative men to better understand what contributes to hormone problems and how common they are.
TaipeiAges 20 years+ - NCT04787848Recruiting
Testing pain causes and treatments in people with HIV
This study looks at why chronic widespread pain happens in people with HIV and tests new ways to understand and treat it. You may be able to join if your HIV is stable on treatment and you meet pain and safety requirements.
Miami, FloridaAges 19–65 - NCT04851015RecruitingPhase 3
Low-dose TMP-SMX for Pneumocystis pneumonia (PCP)
This Phase 3 study tests whether low-dose trimethoprim-sulfamethoxazole (also called TMP-SMX) can treat Pneumocystis pneumonia (PCP) in people with weakened immune systems. It may help improve treatment while reducing side effects compared with standard dosing.
Montreal, QuebecAges 18–100 - NCT04902443RecruitingPhase 1
Pomalidomide plus nivolumab for virus-related cancers
This trial studies pomalidomide plus nivolumab in people with cancers linked to certain viruses (or hepatitis B/C). It may help the immune system fight the cancer when the disease has returned, progressed, or can’t be fully treated with standard options.
Bethesda, MarylandAges 18–99
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Common questions
- Are there clinical trials for hiv?
- Yes. Clin2 currently lists 611 recruiting hiv studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.