Clinical trials
HPV-Related Carcinoma clinical trials
Below are recruiting hpv-related carcinoma clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05985681RecruitingPhase 1
Vaccine to prevent HPV-related cancers
This trial tests a new vaccine (RG1-VLP) designed to prevent HPV-related cancers. It is for healthy women who have not been vaccinated against HPV before and are willing to receive three doses of the vaccine over several months.
Birmingham, AlabamaAges 18–60 - NCT06628570Recruiting
Screening methods for anal cancer in high-risk adults
This study is looking at ways to screen for anal cancer in people who are at higher risk, such as those with weakened immune systems or a history of abnormal cells in the lower genital tract. It aims to find better methods for early detection.
Miami, FloridaAges 30–80 - NCT04988074RecruitingPhase 2
Test cemiplimab for HPV-positive throat cancer using tumor biomarkers
This Phase 2 trial studies whether cemiplimab (with or without chemotherapy first) can improve treatment for HPV-positive oropharynx throat cancer. It also uses lab “biomarkers” to help guide which treatment you get next.
Baltimore, MarylandAges 18 years+ - NCT06563479RecruitingPhase 3
Personalized vs. standard radiation for HPV-positive throat cancer
This trial compares a personalized, shorter course of radiation therapy to the standard longer course for people with HPV-positive throat cancer. The goal is to see if personalized treatment is just as effective while reducing side effects.
Hartford, ConnecticutAges 18 years+ - NCT05419089RecruitingPhase 2
Testing robotic surgery for HPV-related throat cancer patients
This Phase 2 trial studies a robotic surgery approach for certain HPV-related throat cancers, using HPV blood tests before and after surgery to guide care. If your cancer is HPV-related and your HPV blood test results match the trial targets, you may be able to join and help improve treatment for future patients.
Paramus, New JerseyAges 18 years+ - NCT03061435Recruiting
Screening for anal cancer after high-grade vulvar changes
This trial checks whether anal cancer screening is useful for women age 40 and older who previously had high-grade vulvar pre-cancer (VIN 2/3) or vulvar cancer. It may help find serious problems earlier in people at higher risk.
Toronto, OntarioAges 40 years+ - NCT07178301RecruitingPhase 2
Lower radiation dose for HPV-related throat cancer
This trial tests whether a lower dose of radiation to the neck is safe and effective for people with HPV-related oropharyngeal cancer. It may reduce side effects while still treating the cancer.
Chicago, IllinoisAges 18 years+ - NCT04857528Recruiting
Testing HPV DNA in anal and cervical tumors
This trial checks whether tumor samples contain HPV DNA (genetic material from the HPV virus). The goal is to improve detection in anal and cervical cancers, especially in patients planning standard radiation treatment.
Chicago, IllinoisAges 18 years+ - NCT04900623RecruitingPhase 2
Using HPV blood test to guide treatment for HPV throat cancer
This Phase 2 study tests a “risk-adapted” treatment plan for HPV-related throat cancer, using an HPV DNA blood test to help decide how treatment is done. If your baseline blood test shows detectable HPV DNA, the study may help tailor therapy to your risk and potentially improve outcomes while limiting unnecessary treatment.
Boston, MassachusettsAges 22 years+ - NCT05262010RecruitingPhase 3
HPV vaccine study for Chinese women, ages 9–45
This trial tests an 11-type HPV vaccine to prevent infection from multiple HPV strains. If you enroll, you’ll receive scheduled vaccine doses and have health and gynecologic check-ins to see how well the vaccine works and is tolerated.
Hechi, GuangxiAges 18–45 - NCT05307939RecruitingPhase 2
Using tumor DNA tests to time treatment for HPV throat cancer
This study checks a blood test that looks for HPV tumor DNA to help doctors decide when to start routine treatment after surgery. It may help some people avoid starting treatment too early or too late based on how the test changes after the operation.
Miami, FloridaAges 18 years+ - NCT05639972RecruitingPhase 1/Phase 2
HPV cancer trial using immune T cells made for you
This Phase 1/2 trial tests a one-time infusion of special immune T cells made to recognize your HPV16 tumor. It may help your body attack the cancer, while researchers closely monitor safety and early effectiveness.
New Brunswick, New JerseyAges 18 years+ - NCT05686226RecruitingPhase 2
Trial tests immune cells targeting HPV-16 cancers
This Phase 2 trial tests an immune-cell treatment (E7 TCR T cells) designed to attack cancers caused by HPV type 16. It may help people whose HPV-16+ cancer has come back or not responded to standard treatment.
Bethesda, MarylandAges 18 years+ - NCT05829629RecruitingPhase 1
Test of an HPV vaccine-like treatment for HPV16 in women
This Phase 1 study tests FluBHPVE6E7, a new treatment designed to help the immune system respond to HPV16. It mainly checks safety and the best dose, and may help your body clear or control HPV over time.
BratislavaAges 18–49 - NCT06052033Recruiting
Light therapy vs. laser for persistent cervical changes with HPV
This study compares two treatments—photodynamic therapy using a special light-activated cream and a CO2 laser—to see which works better for clearing low-grade cervical changes caused by a long-lasting high-risk HPV infection. The goal is to find a safe, effective option for women who have had this condition for over a year.
Wenzhou, ZhejiangAges 18–65 - NCT06157151RecruitingPhase 2
New drug plus pembrolizumab for advanced cervical cancer
This trial tests a new experimental drug, PRGN-2009, combined with the immunotherapy pembrolizumab (Keytruda) for people with HPV-related cervical cancer that has come back or spread. It is for those who have already tried pembrolizumab and are looking for another option.
Little Rock, ArkansasAges 18 years+ - NCT06305676Recruiting
A study for early detection of HPV throat cancer
This study looks for early signs of HPV-related throat cancer. If you've just been diagnosed and haven't started treatment, your blood or saliva samples may help improve future screening tests.
Tampa, FloridaAges 18 years+ - NCT06319963RecruitingPhase 1/Phase 2
Lenti-HPV-07 immunotherapy for HPV throat or cervical cancer
This trial tests a new immunotherapy called Lenti-HPV-07 for people with HPV-related throat or cervical cancer. It aims to help your immune system fight the cancer more effectively.
Orlando, FloridaAges 18 years+ - NCT06574087Recruiting
Screening for anal cell changes in women with HPV related gynecological disease
This study looks at how often anal cell changes happen in women who have HPV-related gynecological problems. The goal is to find the best way to screen for these changes early.
Gdynia, Pomeranian VoivodeshipAges Any age - NCT06598176Recruiting
New cervical cancer screening test using self-samples
This study is testing a new way to screen for cervical cancer using a sample you collect yourself. It aims to find a simpler, more accurate method that could replace more invasive tests.
Edegem, AntwerpenAges 25–64 - NCT06640283RecruitingPhase 2
Circulating tumor DNA monitoring for cervical and anal cancer
This trial uses a blood test to track tumor DNA in patients with HPV-related cervical or anal cancer. It aims to see if this test can detect early signs of recurrence after radiation therapy, helping guide follow-up care.
São PauloAges 18 years+ - NCT06702033RecruitingPhase 2
Surgery for HPV-related oropharyngeal cancer
This trial is testing a surgical approach for people with HPV-related oropharyngeal cancer that is stage I or II (but not the very smallest). The goal is to see if removing the tumor through the mouth and taking out neck lymph nodes is effective and safe. It may be an option if you are healthy enough for surgery.
St Louis, MissouriAges 18 years+ - NCT06756269RecruitingPhase 2
HPV vaccine study for people aged 9 to 45
This trial tests a new 15-valent HPV vaccine to see if it is safe and creates a strong immune response. If you are between 9 and 45 years old and have not had an HPV vaccine before, you may be able to join.
Nanning, GuangxiAges 9–45 - NCT07425054RecruitingPhase 2
Chemoradiation with or without immunotherapy for anal cancer
This trial tests whether adding an immunotherapy drug (retifanlimab) to standard chemoradiation improves outcomes for people with locally advanced anal cancer. The treatment is adjusted based on HPV DNA levels in your blood.
Cleveland, OhioAges 18 years+
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HPV-Related Carcinoma trials by city
Studies with a site in or near these metro areas.
HPV-Related Carcinoma trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for hpv-related carcinoma?
- Yes. Clin2 currently lists 27 recruiting hpv-related carcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hpv-related carcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hpv-related carcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.