Clinical trials
Hyperoxia clinical trials
Below are recruiting hyperoxia clinical trials, each written for real people, not researchers. We’re tracking 13 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07465302RecruitingPhase 2
Early high oxygen therapy for spinal cord injury
This study tests giving high levels of oxygen soon after a spinal cord injury to see if it can help recovery. It is for people who are awake but need a breathing tube and have certain types of spinal cord injury in the neck or upper back.
Gainesville, FloridaAges 18–85 - NCT05412810Recruiting
Test air-biomarker changes during ICU breathing machine use
This study looks for chemical “biomarkers” in samples taken during ICU care to better understand what happens during mechanical ventilation. It may help future care by identifying signs that could guide safer breathing-machine treatment.
Columbus, OhioAges 18–110 - NCT03800017Recruiting
Muscle strength and exercise function in lung scarring
This study looks at how well skeletal (muscle) function supports exercise in people with interstitial lung diseases (including idiopathic pulmonary fibrosis). It may help better understand fitness and breathing limits, which can guide rehabilitation choices and future care.
Vancouver, British ColumbiaAges 40–80 - NCT04791488Recruiting
Testing oxygen level effects after diving or oxygen therapy
This study looks at how breathing extra oxygen (hyperoxia) and the body’s immune response change after diving or when people need hyperbaric oxygen therapy. It may help doctors understand what to expect and how to manage recovery after a diving accident.
ToulonAges 18 years+ - NCT05235685Recruiting
Testing muscle fatigue during exercise in COPD and heart failure
This study looks at how tired your muscles get during a controlled cycling exercise test in people who have COPD, and—if applicable—heart failure at the same time. It may help researchers understand exercise limits and how to better support you with these conditions.
Échirolles, Auvergne-Rhône-AlpesAges 18 years+ - NCT05379673Recruiting
Breathing changes with extra oxygen after surgery
This study looks at whether giving extra oxygen during recovery from general anesthesia changes how you breathe after surgery. You may be offered different oxygen levels around the time you wake up to see what helps your breathing most comfortably.
Stanford, CaliforniaAges 18–70 - NCT05467215RecruitingEarly Phase 1
Brief oxygen breathing trial after spinal cord injury
This early-phase study tests whether a short period of breathing extra oxygen (hyperoxia) soon after lying in one position can improve physical function in people with long-term spinal cord injury. If you qualify, the goal is to see whether this treatment can help your body work better after chronic injury.
Edmonton, AlbertaAges 18–65 - NCT05589753RecruitingPhase 1/Phase 2
Testing treatment for sleep breathing problems in people on opioids
This trial studies a treatment approach for sleep-disordered breathing (breathing problems during sleep) in Veterans who take prescription opioids. It may help doctors learn safer ways to manage sleep breathing issues that can be made worse by opioid use.
Detroit, MichiganAges 18–89 - NCT06776731Recruiting
Does extra oxygen during rehab help lung disease patients?
This study tests whether breathing extra oxygen during outpatient pulmonary rehabilitation helps people with COPD. Participants will have their oxygen levels checked during exercise to see if extra oxygen improves their rehab results.
Winterthur, Canton of ZurichAges 18 years+ - NCT07377162Recruiting
Hyperoxia effects on brain blood flow in ICU patients
This trial studies how giving extra oxygen (hyperoxia) affects blood flow in the brain for patients on a breathing machine in the intensive care unit. The goal is to see if short bursts of higher oxygen levels are safe and how they change brain activity.
BrusselsAges 18 years+ - NCT02407028RecruitingPhase 2
Hyperbaric oxygen treatment for severe traumatic brain injury
This Phase 2 trial studies whether breathing oxygen in a pressurized chamber can improve outcomes after a severe traumatic brain injury. It is mainly for people with very low consciousness levels soon after injury, with careful safety checks.
San Diego, CaliforniaAges 16–65 - NCT07659301Recruiting
Breathing extra oxygen after cycling to speed recovery
This study tests how breathing higher-than-normal levels of oxygen for a short time after a hard bike ride affects your recovery. It is designed for competitive road cyclists who want to recover faster and perform better in their next training or race.
Louvain-la-Neuve, Brabant-WallonAges 18–40 - NCT04258774Enrolling by invitation
Breathing challenge during MRI to test brain blood-flow signals
This study uses a breathing challenge while you’re in an MRI to see how blood flow signals in the brain change. It may help researchers better understand how brain imaging signals respond to breathing and oxygen/carbon dioxide levels.
St Louis, MissouriAges 18 years+
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Common questions
- Are there clinical trials for hyperoxia?
- Yes. Clin2 currently lists 13 recruiting hyperoxia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hyperoxia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hyperoxia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.