Clinical trials
Hypoglycemia clinical trials
Below are recruiting hypoglycemia clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04657783Recruiting
French cohort study of people with type 1 diabetes
This study follows people with type 1 diabetes in France to better understand the condition over time. It may help researchers improve future care, especially for how type 1 diabetes starts and is managed from early diagnosis onward.
ParisAges 6–100 - NCT04786262RecruitingPhase 3
Study of VX-880 for long-standing type 1 diabetes
This Phase 3 trial tests how safe, tolerable, and effective VX-880 is for people with type 1 diabetes who have had it for many years. It may help reduce problems related to blood sugar swings, especially severe low blood sugar episodes.
Duarte, CaliforniaAges 18–65 - NCT05221359Recruiting
Safety trial of ExOlin® for adults with hard-to-control type 1 diabetes
This trial checks whether ExOlin® is safe in adults with type 1 diabetes who have had difficult blood sugar control or injection-site skin problems despite insulin pump and continuous glucose monitoring. It’s mainly looking for safety and comfort while using the treatment devices.
StrasbourgAges 18 years+ - NCT05317455RecruitingEarly Phase 1
Studying brain sugar changes in adults with risky low blood sugar
This early-stage study looks at how the brain uses sugar in people with type 1 diabetes who have had severe or hard-to-notice low blood sugar. It may help researchers understand the brain effects of low blood sugar and guide safer care.
New Haven, ConnecticutAges 18–55 - NCT05447806Recruiting
Diabetes decision help after an alert message
This study tests a computer system that helps clinicians make better diabetes decisions when an alert or disease-management message appears. It may help your care by guiding what actions the care team takes next.
Hershey, PennsylvaniaAges 18 years+ - NCT05640947Recruiting
Procedure to reverse bypass using an endoscopic stent
This trial studies a minimally invasive procedure that uses a stent placed through an endoscope to create a new connection in the stomach, with the goal of reversing a Roux-en-y gastric bypass. It may help people whose bypass has led to nutrition problems, severe dumping symptoms, difficult marginal ulcers, or liver scarring that worsens after surgery.
BrugesAges 18 years+ - NCT05933161Recruiting
Testing diabetes blood-sugar tracking for people with an LVAD
This study looks at how well people with an LVAD can manage their blood sugar when they use a continuous glucose monitor app on a smartphone. It may help your diabetes care team adjust treatment using more complete sugar data.
Rochester, MinnesotaAges 18 years+ - NCT05973799Recruiting
Fasting test in people with type 1 diabetes
This study looks at how your body responds to low blood sugar during a controlled period of fasting. It may help doctors understand the natural defenses your body uses to prevent dangerous lows in type 1 diabetes.
Cincinnati, OhioAges 18–45 - NCT06234787Recruiting
Continuous glucose monitoring in ICU patients
This study looks at how well continuous glucose monitors (small sensors under the skin that track sugar levels) work in ICU patients who need insulin. If you are in the ICU, on insulin, and already have a sensor, you may be able to join.
MadridAges 18 years+ - NCT06297980Recruiting
Periods, blood sugar, and exercise in type 1 diabetes
This study looks at how your menstrual cycle affects your blood sugar and how you respond to exercise if you have type 1 diabetes. It aims to help women manage their diabetes better throughout the month.
Aurora, ColoradoAges 18–45 - NCT06325202Recruiting
A study on preventing low blood sugar with a closed loop system
This trial tests whether a closed-loop insulin pump combined with education can help people with type 1 diabetes better recognize and avoid dangerously low blood sugar. It may be a good fit if you've had diabetes for a long time and have trouble sensing when your blood sugar drops.
La Jolla, CaliforniaAges 18–75 - NCT07696273Recruiting
Breath test for detecting high and low blood sugar
This trial tests a new breath-based sensor to detect low or high blood sugar (hypoglycemia or hyperglycemia) in people with type 1 or type 2 diabetes. It might offer a non-invasive way to monitor glucose levels.
Indianapolis, IndianaAges 7–25 - NCT06382350Recruiting
Blood sugar changes while driving with a closed-loop insulin pump
This study looks at how blood sugar levels change while driving in people with type 1 diabetes who use a closed-loop insulin pump (MiniMed 780G) compared to those who give multiple daily injections and use a continuous glucose monitor. The goal is to see which method helps keep blood sugar more stable during driving.
PragueAges 18 years+ - NCT06470295RecruitingEarly Phase 1
C-peptide's effect on low blood sugar response
This study tests whether C-peptide (a substance made by the pancreas) can help your body respond better to low blood sugar (hypoglycemia). It's a very early trial for people without certain health conditions.
Cincinnati, OhioAges 18–40 - NCT06563687Recruiting
Continuous glucose monitoring for HIE newborns
This study tests a continuous glucose monitor (CGM) in newborns with hypoxic-ischemic encephalopathy (HIE) — a type of brain injury from lack of oxygen around birth. The CGM tracks sugar levels to help doctors manage care better.
AvellinoAges Up to 6 hours - NCT06794307Recruiting
Blood sugar in pregnant women receiving betamethasone for preterm birth
This study looks at how betamethasone, a steroid given to help babies' lungs mature, affects blood sugar levels in pregnant women without diabetes. It may help ensure safer treatment for women at risk of early labor.
Aarhus, Central Region DenmarkAges 18 years+ - NCT06893341Recruiting
Breath Device to Detect Blood Sugar Changes in Teens
This study tests if a breath device can spot high or low blood sugar in teens with type 1 diabetes without a fingerstick. Participants will use the device a few times and share their CGM data.
Indianapolis, IndianaAges 12–19 - NCT06993103RecruitingPhase 4
Pasteurized donor milk for newborns of mothers with diabetes
This trial tests if giving pasteurized donor human milk to newborns of mothers with diabetes can help their health. It compares donor milk to regular baby formula as a supplement when extra feeding is needed soon after birth.
Brisbane, QueenslandAges birth–2 days - NCT07126873RecruitingPhase 1/Phase 2
Study of E-islet 01 for type 1 diabetes with severe low blood sugar
This study tests a new treatment called E-islet 01, which may help people with type 1 diabetes who have very low natural insulin production and have had dangerous low blood sugar events. The goal is to see if it is safe and can reduce those episodes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07212075Recruiting
Digital twin study for mental health in diabetes
This study uses digital twins—a virtual model of your health—to track how your mental health changes with diabetes. It aims to find patterns that could help personalize mental health care.
Bad Mergentheim, Baden-WurttembergAges 18–80 - NCT07302412Recruiting
Father's touch for newborns at risk of low blood sugar
This study tests if a father's gentle touch (like holding or stroking) can help newborns at risk for low blood sugar stay calm, suck better, and keep stable blood sugar. It aims to see if simple skin-to-skin contact from dad makes a difference in the critical first hours.
Istanbul, IstanbulAges 1 hour–6 hours - NCT00001276Recruiting
Understanding and Treating Severe Low Blood Sugar
This study helps doctors diagnose and treat dangerously low blood sugar, especially in people with pancreatic tumors that produce too much insulin. You'll receive comprehensive evaluation and personalized care to manage your condition.
Bethesda, MarylandAges 18–120 - NCT00992901RecruitingEarly Phase 1
Testing hormones and nerve signals after gastric bypass
This early-phase study looks at how the body’s hormone signals and nerve control affect insulin release after gastric bypass surgery. It may help researchers understand what drives low blood sugar and how to better monitor or treat it.
San Antonio, TexasAges 18–65 - NCT02823665RecruitingEarly Phase 1
Compare how bariatric surgery affects blood sugar changes
This early trial studies how blood sugar moves in people after certain weight-loss surgery compared with people without surgery. It may help researchers understand why blood sugar can drop too low and how treatments like atropine affect that process.
San Antonio, TexasAges 18–65
Hear when a new Hypoglycemia trial opens
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Common questions
- Are there clinical trials for hypoglycemia?
- Yes. Clin2 currently lists 50 recruiting hypoglycemia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hypoglycemia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hypoglycemia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.