Clinical trials
Type 1 Diabetes Mellitus With Hypoglycemia clinical trials
Below are recruiting type 1 diabetes mellitus with hypoglycemia clinical trials, each written for real people, not researchers. We’re tracking 86 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03746769RecruitingPhase 1/Phase 2
Testing gastrin to improve results of islet cell transplant
This trial looks at whether adding gastrin can improve outcomes after an islet cell transplant for people with type 1 diabetes. It may help some participants achieve better blood sugar control, but it also requires close follow-up and immune-suppressing medications to protect the new cells.
Duarte, CaliforniaAges 18–68 - NCT05221359Recruiting
Safety trial of ExOlin® for adults with hard-to-control type 1 diabetes
This trial checks whether ExOlin® is safe in adults with type 1 diabetes who have had difficult blood sugar control or injection-site skin problems despite insulin pump and continuous glucose monitoring. It’s mainly looking for safety and comfort while using the treatment devices.
StrasbourgAges 18 years+ - NCT05553093RecruitingPhase 4
Tirzepatide vs insulin for diabetes and brain effects
This study tests how tirzepatide and insulin glargine affect blood sugar, fat metabolism, and brain function in adults with type 2 diabetes. It may help researchers learn which treatment changes diabetes-related body and brain processes.
Nanjing, JiangsuAges 18–75 - NCT04657783Recruiting
French cohort study of people with type 1 diabetes
This study follows people with type 1 diabetes in France to better understand the condition over time. It may help researchers improve future care, especially for how type 1 diabetes starts and is managed from early diagnosis onward.
ParisAges 6–100 - NCT05363761RecruitingPhase 1
Artery procedure to treat type 2 diabetes and related problems
This Phase 1 study tests a new artery “ablation” procedure for people with type 2 diabetes, aiming to improve diabetes and related conditions like high blood pressure. It will also check whether the procedure is safe and works well enough to study further.
Panama CityAges 21–65 - NCT05369065RecruitingPhase 1
Artery ablation for type 2 diabetes with kidney and liver arteries
This Phase 1 study tests whether a minimally invasive artery procedure can improve type 2 diabetes and related health problems by targeting kidney and liver blood vessels. Because it’s early-stage, the main goal is safety and learning how the treatment works in people who meet specific diabetes, blood pressure, and blood test requirements.
TbilisiAges 21–65 - NCT07829302RecruitingPhase 1/Phase 2
Gene therapy for type 1 diabetes
This trial tests an investigational gene therapy that may help people with type 1 diabetes produce some insulin on their own, potentially reducing the amount of insulin they need. It is an early-stage study, so participants will be closely monitored for safety and any changes in their diabetes control.
MelbourneAges 18–65 - NCT07831798RecruitingPhase 1/Phase 2
Gene therapy for type 1 diabetes
This study tests a new gene therapy (VV-14300) that aims to help people with type 1 diabetes make insulin again. It might improve blood sugar control and reduce the need for insulin.
TorontoAges 18–65 - NCT07814508Recruiting
Continuous glucose monitor app study for insulin users
This study tests a new continuous glucose monitor (CGM) system with a predictive app to help people on insulin therapy manage their blood sugar better. It aims to see if the app improves daily life and glucose control.
Bad Mergentheim, Baden-WurttembergAges 18 years+ - NCT07801820RecruitingPhase 2
Oral diabetes medication study
This study tests an investigational pill for people with type 2 diabetes whose blood sugar is not well controlled despite lifestyle changes or metformin. The pill may help improve blood sugar control and is taken by mouth.
Beijing, Beijing MunicipalityAges 18–75 - NCT07732777Recruiting
AI-assisted insulin pump study for type 1 diabetes
This study tests whether an artificial intelligence (AI) system can help manage insulin pump therapy remotely for people with type 1 diabetes. The goal is to improve blood sugar control and make diabetes management easier.
Nanjing, JiangsuAges 14–65 - NCT07726680Recruiting
Game for kids with new type 1 diabetes
This study tests a fun video game that connects to a continuous glucose monitor (CGM). The game helps kids newly diagnosed with type 1 diabetes learn about managing their condition in a playful way. Both the child and a parent need to join together.
Lahore, Punjab ProvinceAges 6–17 - NCT05887635Recruiting
RF treatment of the duodenum for type 2 diabetes control
This trial tests whether a procedure that uses heat energy (radiofrequency vapor ablation) applied in the first part of the small intestine (duodenum) can improve blood sugar control in adults with type 2 diabetes. It may help lower blood sugar when standard oral medicines are not keeping it in range.
SantiagoAges 18–65 - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Birmingham, AlabamaAges 18 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Sun City, ArizonaAges 18 years+ - NCT07662109RecruitingPhase 3
Testing a new combo pill for type 2 diabetes
This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.
Huntsville, AlabamaAges 18 years+ - NCT07662044RecruitingPhase 3
Studying elecoglipron for type 2 diabetes
This trial tests a new medicine called elecoglipron, taken alone or with another diabetes drug (dapagliflozin), to see if it helps control blood sugar better than a placebo. It may be an option if your current treatment isn't working well enough.
Birmingham, AlabamaAges 18 years+ - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Birmingham, AlabamaAges 18–79 - NCT07650318Recruiting
Virtual reality brain training for diabetes patients with memory issues
This trial tests whether virtual reality brain training can help protect thinking and memory in people with type 2 diabetes who have mild memory problems. If you have type 2 diabetes and notice some mental decline, this study may help you find ways to keep your mind sharp.
Nanjing, JiangsuAges 45–80 - NCT07606872Enrolling by invitation
Testing a diabetes score to guide treatment reversal
This study tests a new scoring system to help people with type 2 diabetes understand their condition better and potentially reverse or improve it. You'll use a digital platform to track blood sugar, answer health questions, and have blood tests to see if the system helps guide your treatment plan.
Manchester, EnglandAges 18 years+ - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Los Angeles, CaliforniaAges 14–75 - NCT06387199RecruitingPhase 2/Phase 3
Weekly semaglutide with closed-loop system for type 1 diabetes
This trial tests whether adding a weekly semaglutide injection (a GLP-1 drug) to a closed-loop insulin system can help reduce the need for carb counting in people with type 1 diabetes. It aims to improve blood sugar control and make diabetes management easier.
Montreal, QuebecAges Any age - NCT07527650RecruitingPhase 2
Testing HM15275 for Type 2 Diabetes Management
This study tests a new medication called HM15275 to help control blood sugar in people with type 2 diabetes. The trial will check if the medication works well and is safe when added to diet, exercise, or metformin treatment.
Mesa, ArizonaAges 18–75 - NCT07518004Recruiting
ROME GS System Study for diabetes glucose monitoring
This study tests the ROME GS System, a glucose monitoring device that measures blood sugar levels. The system includes a sensor placed under the skin and a transmitter worn on the body. If you have diabetes and want to help evaluate a new way to track your blood sugar, this trial may be for you.
Escondido, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for type 1 diabetes mellitus with hypoglycemia?
- Yes. Clin2 currently lists 86 recruiting type 1 diabetes mellitus with hypoglycemia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 1 diabetes mellitus with hypoglycemia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 1 diabetes mellitus with hypoglycemia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.