Type 1 Diabetes Mellitus With Hypoglycemia clinical trials

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

CX11 tablets for type 2 diabetes

This trial tests an experimental drug called CX11 to see if it helps control blood sugar in people with type 2 diabetes who are already taking metformin. It may be an option for you if your blood sugar is not well controlled and you meet the health requirements.

Drug ZT-01 to reduce low blood sugar at night

This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.

Testing a diabetes score to guide treatment reversal

This study tests a new scoring system to help people with type 2 diabetes understand their condition better and potentially reverse or improve it. You'll use a digital platform to track blood sugar, answer health questions, and have blood tests to see if the system helps guide your treatment plan.

Continued access to the Endogenex device study for type 2 diabetes

This trial offers continued access to the Endogenex system for people who were in the sham (placebo) group of the ReCET study and have completed their 12-month visit. It tests a device that treats the duodenum to improve blood sugar control.

Testing HM15275 for Type 2 Diabetes Management

This study tests a new medication called HM15275 to help control blood sugar in people with type 2 diabetes. The trial will check if the medication works well and is safe when added to diet, exercise, or metformin treatment.

Enicepatide for weight loss in people with type 2 diabetes

This trial tests an investigational medication, Enicepatide, to see if it helps people with obesity or overweight and type 2 diabetes lose weight and improve blood sugar control. You will receive weekly injections and regular check-ups.

Treating small blood vessel problems in type 1 diabetes

This study tests whether two different treatment strategies can improve the function of the tiny blood vessels in people with type 1 diabetes. It aims to find a way to prevent or reduce diabetes-related complications.

Testing a new automated insulin pump for people with diabetes

This study tests a new automated insulin delivery system (a pump that helps manage blood sugar) in children and adults with diabetes. It aims to see if the system is safe and easy to use in daily life.

Study of a new pill for weight loss and diabetes

This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.

Tirzepatide for type 1 diabetes: a metabolism study

This study tests if tirzepatide, a medicine that helps lower blood sugar and manage weight, is safe and effective for people with type 1 diabetes who are overweight or have obesity. You must already use an automated insulin pump system.

Donor islet transplant for brittle type 1 diabetes

This study tests a one-time transplant of insulin-making cells from a donor to treat brittle type 1 diabetes—a condition where blood sugar swings wildly and dangerously low. The goal is to help people who still have severe low blood sugar episodes despite intensive insulin therapy.

GLP-1 drug for period problems in teens with type 1 diabetes

This trial tests whether a GLP-1 receptor agonist can help improve irregular periods in teenage girls with type 1 diabetes. It's for girls aged 12 to 18 who have had their period for at least 2 years, use a continuous glucose monitor, and have higher blood sugar levels (HbA1c of 7% or more).

Testing a new combo pill for type 2 diabetes

This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.

A study of elecoglipron for type 2 diabetes with kidney problems

This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).

Studying elecoglipron for type 2 diabetes

This trial tests a new medicine called elecoglipron, taken alone or with another diabetes drug (dapagliflozin), to see if it helps control blood sugar better than a placebo. It may be an option if your current treatment isn't working well enough.

Continuous glucose monitoring for diabetic gastroparesis

This study tests whether a continuous glucose monitor (CGM) can help manage blood sugar in people with diabetes and gastroparesis (slow stomach emptying). If you have type 1 or type 2 diabetes and stomach symptoms, this could help doctors better understand your glucose patterns.

Omnipod 6 Versus Omnipod 5 Insulin Pump System

This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.

Fully Closed Loop Insulin Pump for Type 2 Diabetes

This study tests a new automated insulin pump system (Omnipod) that adjusts insulin doses on its own throughout the day for people with type 2 diabetes. The goal is to see if it helps keep blood sugar levels more stable while reducing the burden of manual insulin management.

AI-assisted insulin pump study for type 1 diabetes

This study tests whether an artificial intelligence (AI) system can help manage insulin pump therapy remotely for people with type 1 diabetes. The goal is to improve blood sugar control and make diabetes management easier.

Game for kids with new type 1 diabetes

This study tests a fun video game that connects to a continuous glucose monitor (CGM). The game helps kids newly diagnosed with type 1 diabetes learn about managing their condition in a playful way. Both the child and a parent need to join together.

Inhaled insulin vs injected insulin for exercise blood sugar drops in type 1 diabetes

This trial tests whether a new inhaled insulin (Technosphere) causes fewer low blood sugar episodes during exercise compared to standard injected insulin in people with type 1 diabetes who use an automated insulin pump. It may help you avoid hypoglycemia while staying active.

Testing gastrin to improve results of islet cell transplant

This trial looks at whether adding gastrin can improve outcomes after an islet cell transplant for people with type 1 diabetes. It may help some participants achieve better blood sugar control, but it also requires close follow-up and immune-suppressing medications to protect the new cells.

Elecoglipron vs semaglutide for type 2 diabetes

This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.