Clinical trials
Hysterectomy clinical trials
Below are recruiting hysterectomy clinical trials, each written for real people, not researchers. We’re tracking 85 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04886791Recruiting
Compare two ways to remove the uterus through the vagina
This study compares a newer “vaginal NOTES” approach with the standard way of removing the uterus through the vagina. It may help find which method is safer or easier for people who need a hysterectomy for non-cancer (benign) reasons.
Eindhoven, North BrabantAges 18 years+ - NCT05884658Recruiting
Natural-orifice vaginal hysterectomy vs laparoscopic hysterectomy
This trial compares two surgical approaches to remove a large, non-cancerous uterus (hysterectomy): a vaginal “through natural opening” endoscopic method versus the usual laparoscopic approach. It aims to see how these options compare for safety and recovery when the uterus is too large for simpler surgery.
BronAges 18 years+ - NCT06289751RecruitingPhase 2
Chemo-immunotherapy before surgery for stage IB2 cervical cancer
This trial tests if giving chemotherapy plus an immunotherapy drug before surgery can help shrink tumors and improve outcomes for patients with stage IB2 cervical cancer that has not been treated yet. It might be an option if you have a specific type of cervical cancer that shows a certain protein (PD-L1) on your tumor cells.
Wuhan, HubeiAges 18–70 - NCT07784465Recruiting
Biofeedback and pelvic floor training after hysterectomy
This study tests whether adding biofeedback to pelvic floor muscle training improves sexual function and quality of life after hysterectomy. Biofeedback is a technique that uses sensors to help you better control your pelvic muscles.
Kafr ash Shaykh, KafrelsheikhAges 45–50 - NCT07626684Enrolling by invitation
Ice Pack After Minimally Invasive Hysterectomy Surgery
This study tests whether applying ice packs to the abdomen after a minimally invasive hysterectomy (removal of the uterus through the vagina) helps reduce pain and speed recovery. You would be randomly assigned to either receive ice pack treatment or standard care.
MuğlaAges 48–70 - NCT06867614Recruiting
Belly-scope vs. vaginal closure after uterus removal
This study compares two ways to close the top of the vagina after a laparoscopic hysterectomy (keyhole removal of the uterus) – one done through small belly incisions and one through the vagina itself. It looks at which method works better for healing and recovery.
CairoAges Any age - NCT06404931RecruitingPhase 2
New material for vaginal prolapse repair
This trial tests a new material made from donated human tissue to repair pelvic organ prolapse. It may help women with certain types of prolapse who have not had prior pelvic surgery.
TerrassaAges 18–100 - NCT05728281Recruiting
See how time after hysterectomy affects sexual function
This study looks at how sexual well-being changes over time after a hysterectomy (removal of the uterus). It may help doctors better understand what to expect and how to support recovery related to sexual function.
AngersAges 18 years+ - NCT07233811Recruiting
Same-day discharge after robotic hysterectomy
This trial tests if it's safe and beneficial to go home the same day after robotic hysterectomy, compared to staying overnight. It includes women with both benign conditions and endometrial cancer, regardless of weight or uterus size.
StockholmAges 18–75 - NCT04929769Recruiting
Surgery trial for early cervical cancer using radical hysterectomy
This trial studies whether a radical hysterectomy—performed either through laparoscopy or an open abdominal operation—works best for certain early-stage cervical cancers. It may help improve cancer control and guide how doctors choose the best surgical approach for your stage.
Shanghai, Shanghai MunicipalityAges 21–70 - NCT04934982Recruiting
Surgery trial for early-stage cervical cancer with lymph vessel invasion
This trial studies whether a specific type of surgery (done through the abdomen or with keyhole surgery) is the right treatment for certain early cervical cancers. It aims to see how well these surgeries work when cancer hasn’t spread to lymph nodes.
ShanghaiAges 21–70 - NCT04939831Recruiting
Surgery study for certain stages of cervical cancer
This trial looks at two surgical approaches to remove the cervix in people with specific early-to-mid stage cervical cancer. It aims to see which approach is safer and/or works better for cancer control based on your cancer stage and scan results.
Shanghai, Shanghai MunicipalityAges 21–70 - NCT06307886Recruiting
Uterine manipulator in endometrial cancer surgery
This trial compares survival rates for patients with early-stage endometrial cancer who have laparoscopic hysterectomy with or without a uterine manipulator (a tool used during surgery).
IstanbulAges 18–75 - NCT04014829Recruiting
Study of pain processing after planned hysterectomy
This trial looks at how the nervous system and fear of pain may affect pain after a planned hysterectomy. If you qualify, you may be asked about pain levels and pain sensitivity to better understand who may have more pain recovery challenges.
SingaporeAges 21–80 - NCT07062367Recruiting
Anesthesia options for laparoscopic hysterectomy and brain health
This study compares three ways to give anesthesia during laparoscopic hysterectomy: one type of gas (sevoflurane) with or without a lidocaine IV drip, versus a different IV anesthesia (propofol). The goal is to see which approach best protects pressure inside your head and oxygen levels in your brain during surgery.
Tanta, El-GharbiaAges 18–65 - NCT06815393Recruiting
Comparing two pain relief methods for abdominal hysterectomy
This trial compares two different pain relief methods for women having abdominal hysterectomy (surgery to remove the uterus through a cut in the belly). It may help find a better way to manage pain after surgery.
Erzurum, YakutiyeAges 18–65 - NCT06039566RecruitingPhase 3
NAC vs placebo for pain after hysterectomy
This trial tests if a medicine called N-acetylcysteine (NAC) can reduce the need for strong pain pills after hysterectomy surgery. If you are having a laparoscopic or robotic hysterectomy, this study may help you recover with less opioid pain medicine.
Charleston, South CarolinaAges 18 years+ - NCT07606781Recruiting
Nerve Blocks for Pain Relief During Hysterectomy Surgery
This study tests two types of nerve-blocking injections given during abdominal hysterectomy (removal of the uterus) to reduce pain and opioid use after surgery. The goal is to help you recover more comfortably with fewer strong pain medications.
Tanta, El-GharbiaAges 18 years+ - NCT06608082Recruiting
Green dye study after keyhole hysterectomy
This trial looks at blood flow in the vaginal area after a type of hysterectomy (keyhole removal of the uterus). Doctors will inject a safe green dye (indocyanine green) during surgery to see how well the area heals.
Clermont-FerrandAges 18 years+ - NCT06690307RecruitingPhase 4
Comparing two pain medicines after laparoscopic hysterectomy
This study compares two pain medicines, oxycodone and sufentanil, given through a pump you control after a laparoscopic hysterectomy. The goal is to see which one provides better pain relief with fewer side effects.
Nantong, JiangsuAges 18–65 - NCT06348719Recruiting
Robot vs. standard laparoscopy for early endometrial cancer
This trial compares two types of minimally invasive surgery (robot-assisted vs. conventional laparoscopy) for removing the uterus in people with early-stage, low- to intermediate-risk endometrial cancer. The goal is to see which approach offers the best value and outcomes.
LilleAges 18 years+ - NCT06642649Recruiting
Comparing anesthesia types to reduce opioids in hysterectomy
This study compares general anesthesia alone to two types of combined anesthesia (general plus spinal) to see which reduces the amount of opioid painkillers needed during and after a laparoscopic hysterectomy. It may help patients recover with less reliance on strong pain medications.
Bellinzona, SwitzerlandAges 18 years+ - NCT07430488Recruiting
Reading a book to help emotions after hysterectomy
This trial tests if reading a personal story about hysterectomy can help women of childbearing age manage their emotions after surgery. It aims to see if this simple activity reduces stress and improves emotional well-being.
BordeauxAges 18–42 - NCT03719547Recruiting
Robot surgery for certain early cervical cancer cases
This trial studies whether robot-assisted surgery can be used safely and effectively for certain early-stage cervical cancers. It may help by using a precise surgical approach to remove the cancer while matching standard care for eligible patients.
StockholmAges 18 years+
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Common questions
- Are there clinical trials for hysterectomy?
- Yes. Clin2 currently lists 85 recruiting hysterectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hysterectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hysterectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.