Clinical trials
Hysterectomy, Vaginal clinical trials
Below are recruiting hysterectomy, vaginal clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06404931RecruitingPhase 2
New material for vaginal prolapse repair
This trial tests a new material made from donated human tissue to repair pelvic organ prolapse. It may help women with certain types of prolapse who have not had prior pelvic surgery.
TerrassaAges 18–100 - NCT04886791Recruiting
Compare two ways to remove the uterus through the vagina
This study compares a newer “vaginal NOTES” approach with the standard way of removing the uterus through the vagina. It may help find which method is safer or easier for people who need a hysterectomy for non-cancer (benign) reasons.
Eindhoven, North BrabantAges 18 years+ - NCT05884658Recruiting
Natural-orifice vaginal hysterectomy vs laparoscopic hysterectomy
This trial compares two surgical approaches to remove a large, non-cancerous uterus (hysterectomy): a vaginal “through natural opening” endoscopic method versus the usual laparoscopic approach. It aims to see how these options compare for safety and recovery when the uterus is too large for simpler surgery.
BronAges 18 years+ - NCT07213635RecruitingPhase 4
Numbing injection for pain after hysterectomy for prolapse
This trial tests whether a numbing injection into the cervix can reduce the need for opioid pain medicine after vaginal hysterectomy for prolapse. It aims to find a safer, effective pain control option.
Raleigh, North CarolinaAges 18 years+ - NCT07626684Enrolling by invitation
Ice Pack After Minimally Invasive Hysterectomy Surgery
This study tests whether applying ice packs to the abdomen after a minimally invasive hysterectomy (removal of the uterus through the vagina) helps reduce pain and speed recovery. You would be randomly assigned to either receive ice pack treatment or standard care.
MuğlaAges 48–70 - NCT07174921Recruiting
Vaginal cuff prolapse repair after hysterectomy
This trial tests a surgery to fix vaginal cuff prolapse (when the top of the vagina drops down) in women who have had a hysterectomy. It may help relieve symptoms and improve quality of life.
Istanbul, IstanbulAges 18 years+ - NCT07067645Recruiting
Vaginal length after hysterectomy: comparing two closure methods
This trial compares two ways of closing the vagina after a hysterectomy for severe uterine prolapse to see which method keeps more vaginal length. It may help women who want to preserve vaginal depth after surgery.
IstanbulAges 35–65 - NCT07226375Recruiting
Trial comparing two hysterectomy methods for large uteri
This study tests a new device that cuts and removes tissue through a tiny camera during laparoscopic hysterectomy. It may help women with very large uteri have a less invasive surgery compared to the standard cold scalpel method.
IzmirAges 35–65 - NCT07566949Recruiting
Finnish study comparing uterine prolapse surgery options
This study compares two surgical approaches for women with moderate-to-severe uterine prolapse (when the uterus drops into the vagina). The trial tests whether keeping your uterus during surgery works as well as removing it, with follow-up care over time.
HelsinkiAges 18–100 - NCT07379411Recruiting
Energy devices vs. cold scalpel for tube and ovary removal during vaginal hysterectomy
This trial is comparing two ways to remove the fallopian tubes and ovaries during a vaginal hysterectomy for pelvic organ prolapse: one using energy-based devices (like a cauterizing tool) and the other using a standard cold scalpel method. It will help determine if the energy-based approach offers any benefits, such as less blood loss or faster recovery.
HolonAges 18 years+ - NCT07313839Recruiting
Comparing two suture types for vaginal vault closure after hysterectomy
This trial tests if a self-locking suture works better than a traditional one when closing the vaginal vault during laparoscopic or robotic hysterectomy for gynecologic cancer. It aims to find a safer and more effective method for this part of the surgery.
Parma, ItalyAges 18 years+ - NCT06867614Recruiting
Belly-scope vs. vaginal closure after uterus removal
This study compares two ways to close the top of the vagina after a laparoscopic hysterectomy (keyhole removal of the uterus) – one done through small belly incisions and one through the vagina itself. It looks at which method works better for healing and recovery.
CairoAges Any age - NCT05969457RecruitingPhase 3
Local pain-numbing injection before surgery for hysterectomy
This Phase 3 study tests whether a preventive numbing medicine injection before a vaginal hysterectomy (using the vNOTES approach) can reduce pain afterward. It may help with comfort and recovery after surgery for non-cancer reasons.
Le HavreAges 18–70 - NCT06024109Recruiting
Comparing two stitches for laparoscopic hysterectomy
This trial compares two types of stitches (SYMMCORA vs. V-Loc) used during laparoscopic hysterectomy to see which one works best. It is for women having planned keyhole removal of the uterus.
Frankfurt am Main, HesseAges 18 years+ - NCT05682989Recruiting
Testing mesh surgery for pelvic organ prolapse symptoms
This trial studies how well and how safely a synthetic mesh surgery works for people with pelvic organ prolapse, especially when it causes bladder or urinary problems. It may help find better symptom relief, but it also tracks side effects closely.
New Taipei CityAges 30–100 - NCT06608082Recruiting
Green dye study after keyhole hysterectomy
This trial looks at blood flow in the vaginal area after a type of hysterectomy (keyhole removal of the uterus). Doctors will inject a safe green dye (indocyanine green) during surgery to see how well the area heals.
Clermont-FerrandAges 18 years+ - NCT06719180RecruitingPhase 4
Pain relief after a hysterectomy
This study tests if numbing the top of the vagina (vaginal cuff) with a local anesthetic can reduce the need for pain medicine after a hysterectomy done by laparoscopy (small cuts in the belly). If you are having this surgery for a non-cancerous condition or cancer, you may be able to join.
Flushing, New YorkAges 18 years+
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Common questions
- Are there clinical trials for hysterectomy, vaginal?
- Yes. Clin2 currently lists 17 recruiting hysterectomy, vaginal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hysterectomy, vaginal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hysterectomy, vaginal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.